Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia

Title: Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia

Volume: 10 Issue: 4

Author(s): Josep M. Argiles, Miriam Toledo, Francisco J. Lopez-Soriano and Silvia Busquets

Affiliation:

Keywords: TNF-, IL-6, IL-1, TWEAK, myostatin, PIF, transcriptional factors, cancer cachexia, anorexia

Abstract: The main aim of the present review is to summarize and evaluate the different molecular mechanisms and catabolic mediators (mainly cytokines) involved in cancer cachexia since they may represent targets for future promising clinical investigations.

Cite this article as:

M. Argiles Josep, Toledo Miriam, J. Lopez-Soriano Francisco and Busquets Silvia, Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2011; 10 (4) . https://dx.doi.org/10.2174/187152311797928199