Cardiovascular Disease in Diabetes

Title: Cardiovascular Disease in Diabetes

Volume: 6 Issue: 3

Author(s): Sho-ichi Yamagishi, Kazuo Nakamura, Takanori Matsui, Katsuhiko Takenaka, Yuko Jinnouchi and Tsutomu Imaizumi

Affiliation:

Keywords: AGEs, atherosclerosis, diabetes, oxidative stress, renin-angiotensin system

Abstract: Diabetes is associated with a marked increase in the risk of atherosclerotic vascular disorders, including coronary, cerebrovascular, and peripheral artery disease. Cardiovascular disease (CVD) could account for disabilities and high mortality rates in patients with diabetes. In this paper, we review the molecular mechanisms for accelerated atherosclerosis in diabetes, especially focusing on postprandial hyperglycemia, advanced glycation end products (AGEs) and the renin-angiotensin system. We also discuss here the potential therapeutic strategy that specifically targets CVD in patients with diabetes.

Cite this article as:

Yamagishi Sho-ichi, Nakamura Kazuo, Matsui Takanori, Takenaka Katsuhiko, Jinnouchi Yuko and Imaizumi Tsutomu, Cardiovascular Disease in Diabetes, Mini-Reviews in Medicinal Chemistry 2006; 6 (3) . https://dx.doi.org/10.2174/138955706776073501