Recent Advances in Combinatorial Chemistry Applied to Development of Anti-HIV Drugs

S.      Pettersson; I.      Clotet-Codina; J.   A.   Este; J.   I.   Borrell; J.      Teixido

doi:10.2174/138955706775197820

Abstract

A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds.

Keywords: Combinatorial chemistry, synthesis, anti-HIV drugs, high throughput screening

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Mini-Reviews in Medicinal Chemistry

Title: Recent Advances in Combinatorial Chemistry Applied to Development of Anti-HIV Drugs

Volume: 6 Issue: 1

Author(s): S. Pettersson, I. Clotet-Codina, J. A. Este, J. I. Borrell and J. Teixido

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Keywords: Combinatorial chemistry, synthesis, anti-HIV drugs, high throughput screening

Abstract: A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds.

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Pettersson S., Clotet-Codina I., Este A. J., Borrell I. J. and Teixido J., Recent Advances in Combinatorial Chemistry Applied to Development of Anti-HIV Drugs, Mini-Reviews in Medicinal Chemistry 2006; 6 (1) . https://dx.doi.org/10.2174/138955706775197820