Abstract
The radical addition of thiols to double and triple carbon-carbon bonds was examined in typical ionic liquids ([bmim][PF6], [bmim][Tf2N], and [bmim][BF4]) under different temperature/initiator conditions (i.e. 80-100 °C / AIBNVAZO ®, r.t. / triethylborane, r.t. / AIBN / UV radiation, r.t. / photoinitiator / UV radiation). All the addition products were usually obtained with high efficiencies and very good recyclability of the ionic liquid. In some cases, small but significant differences were noticed by changing the reaction medium from benzene to a ionic liquid. The possibility of applying this procedure to click-chemistry reactions with thiols/alkenes of biological interest is also discussed.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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