Abstract
This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.
Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
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