P4PC: A Portal for Bioinformatics Resources of piRNAs and circRNAs

Title:P4PC: A Portal for Bioinformatics Resources of piRNAs and circRNAs

Volume: 19 Issue: 9

Author(s): Yajun Liu*, Ru Li, Yulian Ding, Xin Hong Hei and Fang-Xiang Wu*

Affiliation:

• Shaanxi Key Laboratory for Network Computing and Security Technology, School of Computer Science and Engineering, Xi'an University of Technology, Xi'an 710048, Shaanxi, China

• Division of Biomedical Engineering, Department of Mechanical Engineering, Department of Computer Science, University of Saskatchewan, SK, S7N 5A9, Canada

Abstract:

Background: PIWI-interacting RNAs (piRNAs) and circular RNAs (circRNAs) are two kinds of non-coding RNAs (ncRNAs) that play important roles in epigenetic regulation, transcriptional regulation, post-transcriptional regulation of many biological processes. Although there exist various resources, it is still challenging to select such resources for specific research projects on ncRNAs.

Method: In order to facilitate researchers in finding the appropriate bioinformatics sources for studying ncRNAs, we created a novel portal named P4PC that provides computational tools and data sources of piRNAs and circRNAs.

Result: 249 computational tools, 126 databases and 420 papers are manually curated in P4PC. All entries in P4PC are classified in 5 groups and 26 subgroups. The list of resources is summarized in the first page of each group.

Conclusion: According to their research proposes, users can quickly select proper resources for their research projects by viewing detail information and comments in P4PC. Database URL is http://www.ibiomedical.net/Portal4PC/ and https://43.138.46.5/Portal4PC/.

Cite this article as:

Liu Yajun*, Li Ru, Ding Yulian, Hei Hong Xin and Wu Fang-Xiang*, P4PC: A Portal for Bioinformatics Resources of piRNAs and circRNAs, Current Bioinformatics 2024; 19 (9) . https://dx.doi.org/10.2174/0115748936289420240117100823