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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Cycloaddition Methodology: A Useful Entry Towards Biologically Active Heterocycles

Author(s): Ugo Chiacchio, Albert Padwa and Giovanni Romeo

Volume 13, Issue 5, 2009

Page: [422 - 447] Pages: 26

DOI: 10.2174/138527209787582268

Price: $65

Abstract

The present review contains a representative sampling from the last 10 years on the synthesis of biologically interesting compounds, prepared by the use of the 1,3-dipolar cycloaddition and Diels-Alder reactions, that have been eventually sequenced into cascade processes to assemble heterocyclic molecules. The important role of click chemistry for the synthesis of bio-inspired compounds have been also outlined.

Keywords: Cycloaddition Methodology, Diels-Alder reactions, heterocyclic molecules, synthesis


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