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Infectious Disorders - Drug Targets

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ISSN (Online): 2212-3989

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Review Article

Cracking the Code of Lumpy Skin Disease: Identifying Causes, Symptoms and Treatment Options for Livestock Farmers

Author(s): Devdhar Yadav, GSN Koteswara Rao, Deepika Paliwal*, Amit Singh, Aftab Alam, Pramod Kumar Sharma, Amareswarapu V Surendra, Prachi Varshney and Yogesh Kumar

Volume 24, Issue 5, 2024

Published on: 15 January, 2024

Article ID: e150124225632 Pages: 15

DOI: 10.2174/0118715265261364231120053105

Price: $65

Abstract

The novel bovine viral infection known as lumpy skin disease is common in most African and Middle Eastern countries, with a significant likelihood of disease transfer to Asia and Europe. Recent rapid disease spread in formerly disease-free zones highlights the need of understanding disease limits and distribution mechanisms. Capripox virus, the causal agent, may also cause sheeppox and Goatpox. Even though the virus is expelled through several bodily fluids and excretions, the most common causes of infection include sperm and skin sores. Thus, vulnerable hosts are mostly infected mechanically by hematophagous arthropods such as biting flies, mosquitoes, and ticks. As a result, milk production lowers, abortions, permanent or temporary sterility, hide damage, and mortality occur, contributing to a massive financial loss for countries that raise cattle. These illnesses are economically significant because they affect international trade. The spread of Capripox viruses appears to be spreading because to a lack of effectual vaccinations and poverty in rural areas. Lumpy skin disease has reached historic levels; as a consequence, vaccination remains the only viable option to keep the illness from spreading in endemic as well as newly impacted areas. This study is intended to offer a full update on existing knowledge of the disease's pathological characteristics, mechanisms of spread, transmission, control measures, and available vaccinations.

Graphical Abstract

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