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Current Pharmaceutical Biotechnology

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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Review Article

Bioactive Exploration in Functional Foods: Unlocking Nature's Treasures

Author(s): Ravi K. Mittal*, Raghav Mishra*, Vikram Sharma and Priyank Purohit

Volume 25, Issue 11, 2024

Published on: 28 November, 2023

Page: [1419 - 1435] Pages: 17

DOI: 10.2174/0113892010282580231120041659

Price: $65

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Abstract

Background: Functional foods offer an appealing way to improve health and prevent chronic diseases, and this subject has received much attention lately. They are effective in preventing chronic diseases like cancer, diabetes, heart disease, and obesity, according to research.

Objective: This work presents an in-depth analysis of functional foods, covering key challenges from a scientific, legal, and commercial perspective.

Methods: Multiple databases were searched to find studies on functional foods included in the systematic literature review. Various aspects of functional foods, from their classification, impact on human wellness, effectiveness in inhibiting chronic diseases, the regulatory environment, global market trends, and industry challenges, are all clarified in this thorough review.

Results: This study aims to enhance understanding and establish a pathway for functional foods to be acknowledged as valid choices in the field of dietary supplements. It provides a thorough investigation of bioactive compounds present in functional foods, including but not limited to polyphenols, carotenoids, omega fatty acids, prebiotics, probiotics, and dietary fiber, along with an overview of their potential to mitigate chronic illnesses. We engage in an in-depth exploration of regulatory frameworks, shed light on groundbreaking research advancements, and meticulously examine strategies for commercialization and the variety of global challenges that accompany them. Establishing scientific consensus, navigating complex regulatory processes, dealing with skeptical consumers, and rising levels of competition are all problems that need to be solved in this field.

Conclusion: The field of functional foods can advance further, promoting better public health outcomes, by deeply comprehending and addressing these complex dimensions.

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[1]
Harwansh, R.K.; Deshmukh, R. Breast cancer: An insight into its inflammatory, molecular, pathological and targeted facets with update on investigational drugs. Crit. Rev. Oncol. Hematol., 2020, 154(103070), 103070.
[http://dx.doi.org/10.1016/j.critrevonc.2020.103070] [PMID: 32871325]
[2]
da Cunha Xavier, J.; dos Santos, H.S.; Machado Marinho, M.; Nunes da Rocha, M.; Rodrigues Teixeira, A.M.; Coutinho, H.D.M.; Marinho, E.S. Chalcones as potent agents against staphylococcus aureus: A computational approach. Lett. Drug Des. Discov., 2023, 20.
[http://dx.doi.org/10.2174/1570180820666230120145921]
[3]
Krishna, G.; Shah, K. Current drifts in design and development of prodrugs. ECS Trans., 2022, 107(1), 18939-18956.
[http://dx.doi.org/10.1149/10701.18939ecst]
[4]
Mishra, R.; Chaudhary, K.; Mishra, I. Weapons and strategies against COVID-19: A perspective. Curr. Pharm. Biotechnol., 2023, 25(2), 144-158.
[http://dx.doi.org/10.2174/1389201024666230525161432] [PMID: 37231727]
[5]
Mishra, R.; Chaudhary, K.; Mishra, I. AI in health science: A perspective. Curr. Pharm. Biotechnol., 2023, 24(9), 1149-1163.
[http://dx.doi.org/10.2174/1389201023666220929145220] [PMID: 36177622]
[6]
Shah, K.; Chhabra, S.; Singh Chauhan, N. Chemistry and anticancer activity of cardiac glycosides: A review. Chem. Biol. Drug Des., 2022, 100(3), 364-375.
[http://dx.doi.org/10.1111/cbdd.14096] [PMID: 35638893]
[7]
Isha.; Sachan, N. Design, synthesis and biological assessment of thiazole derivatives as possible antioxidant and antimicrobial agents. J. Pharm. Res. Int., 2021, 33, 24-32.
[http://dx.doi.org/10.9734/jpri/2021/v33i53A33635]
[8]
Mishra, R.; Kumar, N.; Mishra, I.; Sachan, N. A review on anticancer activities of thiophene and its analogs. Mini Rev. Med. Chem., 2020, 20(19), 1944-1965.
[http://dx.doi.org/10.2174/1389557520666200715104555] [PMID: 32669077]
[9]
Mishra, R.; Kumar, N.; Sachan, N. Synthesis, biological evaluation, and docking analysis of novel tetrahydrobenzothiophene derivatives. Lett. Drug Des. Discov., 2022, 19(6), 530-540.
[http://dx.doi.org/10.2174/1570180819666220117123958]
[10]
Mishra, R.; Kumar, N.; Sachan, N. Synthesis, pharmacological evaluation, and in-silico studies of thiophene derivatives. Oncologie, 2021, 23(4), 493-514.
[http://dx.doi.org/10.32604/oncologie.2021.018532]
[11]
Mishra, R.; Sachan, N.; Kumar, N.; Mishra, I.; Chand, P. Thiophene scaffold as prospective antimicrobial agent: A review. J. Heterocycl. Chem., 2018, 55(9), 2019-2034.
[http://dx.doi.org/10.1002/jhet.3249]
[12]
Mishra, R.; Kumar, N.; Sachan, N. Thiophene and its analogs as prospective antioxidant agents: A retrospective study. Mini Rev. Med. Chem., 2022, 22(10), 1420-1437.
[http://dx.doi.org/10.2174/1389557521666211022145458] [PMID: 34719361]
[13]
Goyal, A.; Verma, A.; Dubey, N.; Raghav, J.; Agrawal, A. Naringenin: A prospective therapeutic agent for Alzheimer’s and Parkinson’s disease. J. Food Biochem., 2022, 46(12), e14415.
[http://dx.doi.org/10.1111/jfbc.14415] [PMID: 36106706]
[14]
Murti, Y.; Agrawal, K.K. Tangeretin: A biologically potential citrus flavone. Curr. Tradit. Med., 2022, 8(4), e040322201698.
[http://dx.doi.org/10.2174/2215083808666220304100702]
[15]
Kaurav, M.; Kanoujia, J.; Gupta, M.; Goyal, P.; Pant, S.; Rai, S.; Sahu, K.K.; Bhatt, P.; Ghai, R. In-Depth Analysis of the Chemical Composition, Pharmacological Effects, Pharmacokinetics, and Patent History of Mangiferin: Mangiferin as Herbal Medicine with Diverse Therapeutic Activities; Phytomed; Plus, 2023.
[http://dx.doi.org/10.1016/j.phyplu.2023.100445]
[16]
Roberfroid, M.B. Global view on functional foods: European perspectives. Br. J. Nutr., 2002, 88(S2)(Suppl. 2), S133-S138.
[http://dx.doi.org/10.1079/BJN2002677] [PMID: 12495454]
[17]
Bigliardi, B.; Galati, F. Innovation trends in the food industry: The case of functional foods. Trends Food Sci. Technol., 2013, 31(2), 118-129.
[http://dx.doi.org/10.1016/j.tifs.2013.03.006]
[18]
Arai, S. Studies on functional foods in Japan--state of the art. Biosci. Biotechnol. Biochem., 1996, 60(1), 9-15.
[http://dx.doi.org/10.1271/bbb.60.9] [PMID: 8824819]
[19]
Ohama, H.; Ikeda, H.; Moriyama, H. Health foods and foods with health claims in japan. In: Nutraceutical and Functional Food Regulations in the United States and Around the World; Elsevier, 2008; pp. 249-280.
[http://dx.doi.org/10.1016/B978-012373901-8.00017-2]
[20]
Swinbanks, D.; O’Brien, J. Japan explores the boundary between food and medicine. Nature, 1993, 364(6434), 180.
[http://dx.doi.org/10.1038/364180a0] [PMID: 8321303]
[21]
Barauskaite, D.; Gineikiene, J.; Fennis, B.M.; Auruskeviciene, V.; Yamaguchi, M.; Kondo, N. Eating healthy to impress: How conspicuous consumption, perceived self-control motivation, and descriptive normative influence determine functional food choices. Appetite, 2018, 131, 59-67.
[http://dx.doi.org/10.1016/j.appet.2018.08.015] [PMID: 30114492]
[22]
Butnariu, M.; Sarac, I. Functional Food. Int. J. Nutr., 2019, 3(3), 7-16.
[http://dx.doi.org/10.14302/issn.2379-7835.ijn-19-2615]
[23]
Shi, J.; Mazza, G.; Le Maguer, M. Functional foods; Biochemical and Processing Aspects, 2016, p. 2.
[http://dx.doi.org/10.1016/S0144-8617(01)00362-9]
[24]
Henry, C.J. Functional foods. Eur. J. Clin. Nutr., 2010, 64(7), 657-659.
[http://dx.doi.org/10.1038/ejcn.2010.101] [PMID: 20606685]
[25]
Topolska, K.; Florkiewicz, A.; Filipiak-Florkiewicz, A. Functional food—consumer motivations and expectations. Int. J. Environ. Res. Public Health, 2021, 18(10), 5327.
[http://dx.doi.org/10.3390/ijerph18105327] [PMID: 34067768]
[26]
Bimbo, F.; Bonanno, A.; Nocella, G.; Viscecchia, R.; Nardone, G.; De Devitiis, B.; Carlucci, D. Consumers’ acceptance and preferences for nutrition-modified and functional dairy products: A systematic review. Appetite, 2017, 113, 141-154.
[http://dx.doi.org/10.1016/j.appet.2017.02.031] [PMID: 28235616]
[27]
Kraus, A.; Annunziata, A.; Vecchio, R. Sociodemographic factors differentiating the consumer and the motivations for functional food consumption. J. Am. Coll. Nutr., 2017, 36(2), 116-126.
[http://dx.doi.org/10.1080/07315724.2016.1228489] [PMID: 28067592]
[28]
Román, S.; Sánchez-Siles, L.M.; Siegrist, M. The importance of food naturalness for consumers: Results of a systematic review. Trends Food Sci. Technol., 2017, 67, 44-57.
[http://dx.doi.org/10.1016/j.tifs.2017.06.010]
[29]
Puhakka, R.; Valve, R.; Sinkkonen, A. Older consumers’ perceptions of functional foods and non‐edible health‐enhancing innovations. Int. J. Consum. Stud., 2018, 42(1), 111-119.
[http://dx.doi.org/10.1111/ijcs.12400]
[30]
Singh, M.P.; Soni, K.; Bhamra, R.; Mittal, R.K. Superfood: Value and need. Curr. Nutr. Food Sci., 2022, 18(1), 65-68.
[http://dx.doi.org/10.2174/1573401317666210420123013]
[31]
Pérez-Jiménez, J.; Neveu, V.; Vos, F.; Scalbert, A. Identification of the 100 richest dietary sources of polyphenols: an application of the Phenol-Explorer database. Eur. J. Clin. Nutr., 2010, 64(S3)(Suppl. 3), S112-S120.
[http://dx.doi.org/10.1038/ejcn.2010.221] [PMID: 21045839]
[32]
Pandey, K.B.; Rizvi, S.I. Plant polyphenols as dietary antioxidants in human health and disease. Oxid. Med. Cell. Longev., 2009, 2(5), 270-278.
[http://dx.doi.org/10.4161/oxim.2.5.9498] [PMID: 20716914]
[33]
Robards, K.; Antolovich, M. Analytical chemistry of fruit bioflavonoidsa review. Analyst, 1997, 122(2), 11R-34R.
[http://dx.doi.org/10.1039/a606499j]
[34]
Sung, H.Y.; Hong, C.G.; Suh, Y.S.; Cho, H.C.; Park, J.H.; Bae, J.H.; Park, W.K.; Han, J.; Song, D.K. Role of (−)-epigallocatechin-3-gallate in cell viability, lipogenesis, and retinol-binding protein 4 expression in adipocytes. Naunyn Schmiedebergs Arch. Pharmacol., 2010, 382(4), 303-310.
[http://dx.doi.org/10.1007/s00210-010-0547-0] [PMID: 20711765]
[35]
Tanaka, M.; Zhao, J.; Suyama, A.; Matsui, T. Epigallocatechin gallate promotes the vasorelaxation power of the antiatherosclerotic dipeptide Trp-His in contracted rat aorta. J. Agric. Food Chem., 2012, 60(36), 9048-9054.
[http://dx.doi.org/10.1021/jf3010228] [PMID: 22900606]
[36]
Spencer, J.P.E. The impact of fruit flavonoids on memory and cognition. Br. J. Nutr., 2010, 104(3), 40-47.
[http://dx.doi.org/10.1017/S0007114510003934]
[37]
Khan, N.; Mukhtar, H. Tea polyphenols in promotion of human health. Nutrients, 2018, 11(1), 39.
[http://dx.doi.org/10.3390/nu11010039] [PMID: 30585192]
[38]
Boots, A.W.; Haenen, G.R.M.M.; Bast, A. Health effects of quercetin: From antioxidant to nutraceutical. Eur. J. Pharmacol., 2008, 585(2-3), 325-337.
[http://dx.doi.org/10.1016/j.ejphar.2008.03.008] [PMID: 18417116]
[39]
Luo, Q.; Zhang, J.R.; Li, H.B.; Wu, D.T.; Geng, F.; Corke, H.; Wei, X.L.; Gan, R.Y. Green extraction of antioxidant polyphenols from green tea (Camellia sinensis). Antioxidants, 2020, 9(9), 785.
[http://dx.doi.org/10.3390/antiox9090785] [PMID: 32854245]
[40]
Nile, S.H.; Kim, S.H.; Ko, E.Y.; Park, S.W. Polyphenolic contents and antioxidant properties of different grape (V. vinifera, V. labrusca, and V. hybrid) cultivars. BioMed Res. Int., 2013, 2013, 1-5.
[http://dx.doi.org/10.1155/2013/718065] [PMID: 24027762]
[41]
Kulichová, K.; Sokol, J. Nemeček, P.; Maliarová, M.; Maliar, T.; Havrlentová, M.; Kraic, J. Phenolic compounds and biological activities of rye (Secale cereale L.) grains. Open Chem., 2019, 17(1), 988-999.
[http://dx.doi.org/10.1515/chem-2019-0103]
[42]
Gong, K.; Chen, L.; Li, X.; Sun, L.; Liu, K. Effects of germination combined with extrusion on the nutritional composition, functional properties and polyphenol profile and related in vitro hypoglycemic effect of whole grain corn. J. Cereal Sci., 2018, 83, 1-8.
[http://dx.doi.org/10.1016/j.jcs.2018.07.002]
[43]
Tong, T.; Liu, Y.J.; Kang, J.; Zhang, C.M.; Kang, S.G. Antioxidant activity and main chemical components of a novel fermented tea. Molecules, 2019, 24(16), 2917.
[http://dx.doi.org/10.3390/molecules24162917] [PMID: 31408939]
[44]
Sandhu, K.S.; Punia, S. Enhancement of bioactive compounds in barley cultivars by solid substrate fermentation. J. Food Meas. Charact., 2017, 11(3), 1355-1361.
[http://dx.doi.org/10.1007/s11694-017-9513-6]
[45]
Kerienė I.; Mankevičienė A.; Bliznikas, S.; Jablonskytė-Raščė D.; Maikštėnienė S.; Česnulevičienė R. Biologically active phenolic compounds in buckwheat, oats and winter spelt wheat. Zemdirbyste, 2015, 102(3), 289-296.
[http://dx.doi.org/10.13080/z-a.2015.102.037]
[46]
Singla, R.K.; Dubey, A.K.; Garg, A.; Sharma, R.K.; Fiorino, M.; Ameen, S.M.; Haddad, M.A.; Al-Hiary, M. Natural polyphenols: Chemical classification, definition of classes, subcategories, and structures. J. AOAC Int., 2019, 102(5), 1397-1400.
[http://dx.doi.org/10.5740/jaoacint.19-0133] [PMID: 31200785]
[47]
Johnson, E.J. The role of carotenoids in human health. Nutr. Clin. Care, 2002, 5(2), 56-65.
[http://dx.doi.org/10.1046/j.1523-5408.2002.00004.x] [PMID: 12134711]
[48]
Stahl, W.; Sies, H. Antioxidant activity of carotenoids. Mol. Aspects Med., 2003, 24(6), 345-351.
[http://dx.doi.org/10.1016/S0098-2997(03)00030-X] [PMID: 14585305]
[49]
Agarwal, S. Rao, Α.V. Carotenoids and chronic diseases. Drug Metabol. Drug Interact., 2000, 17(1-4), 189-210.
[http://dx.doi.org/10.1515/DMDI.2000.17.1-4.189] [PMID: 11201295]
[50]
Krinsky, N.I. Carotenoids as antioxidants. Nutrition, 2001, 17(10), 815-817.
[http://dx.doi.org/10.1016/S0899-9007(01)00651-7] [PMID: 11684386]
[51]
Bone, R.A.; Landrum, J.T.; Tarsis, S.L. Preliminary identification of the human macular pigment. Vision Res., 1985, 25(11), 1531-1535.
[http://dx.doi.org/10.1016/0042-6989(85)90123-3] [PMID: 3832576]
[52]
Maria, A.G.; Graziano, R.; Nicolantonio, D.O. Carotenoids: potential allies of cardiovascular health? Food Nutr. Res., 2015, 59(1), 26762.
[http://dx.doi.org/10.3402/fnr.v59.26762] [PMID: 25660385]
[53]
Surh, Y.J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer, 2003, 3(10), 768-780.
[http://dx.doi.org/10.1038/nrc1189] [PMID: 14570043]
[54]
Arballo, J.; Amengual, J.; Erdman, J.W. Jr Lycopene: A critical review of digestion, absorption, metabolism, and excretion. Antioxidants, 2021, 10(3), 342.
[http://dx.doi.org/10.3390/antiox10030342] [PMID: 33668703]
[55]
Wellala, C.K.D.; Bi, J.; Liu, X.; Wu, X.; Lyu, J.; Liu, J.; Liu, D.; Guo, C. Effect of high pressure homogenization on water-soluble pectin characteristics and bioaccessibility of carotenoids in mixed juice. Food Chem., 2022, 371(131073), 131073.
[http://dx.doi.org/10.1016/j.foodchem.2021.131073] [PMID: 34537621]
[56]
Papapostolou, H.; Kachrimanidou, V.; Alexandri, M.; Plessas, S.; Papadaki, A.; Kopsahelis, N. Natural carotenoids: Recent advances on separation from microbial biomass and methods of analysis. Antioxidants, 2023, 12(5), 1030.
[http://dx.doi.org/10.3390/antiox12051030] [PMID: 37237896]
[57]
Irwandi Jaswir. Noviendri, D.; Hasrini, R.F.; Octavianti, F. Carotenoids: Sources, medicinal properties and their application in food and nutraceutical industry. J. Med. Plants Res., 2011, 5(33)
[http://dx.doi.org/10.5897/JMPRX11.011]
[58]
Ghilardi, C.; Sanmartin Negrete, P.; Carelli, A.A.; Borroni, V. Evaluation of olive mill waste as substrate for carotenoid production by Rhodotorula mucilaginosa. Bioresour. Bioprocess., 2020, 7(1), 52.
[http://dx.doi.org/10.1186/s40643-020-00341-7]
[59]
Gervasi, T.; Pellizzeri, V.; Benameur, Q.; Gervasi, C.; Santini, A.; Cicero, N.; Dugo, G. Valorization of raw materials from agricultural industry for astaxanthin and β-carotene production by Xanthophyllomyces dendrorhous. Nat. Prod. Res., 2018, 32(13), 1554-1561.
[http://dx.doi.org/10.1080/14786419.2017.1385024] [PMID: 29017370]
[60]
Sereti, F.; Papadaki, A.; Alexandri, M.; Kachrimanidou, V.; Kopsahelis, N. Exploring the potential of novel R. kratochvilovae red yeasts towards the sustainable synthesis of natural carotenoids. Sustain. Chem. Pharm., 2023, 31, 100927.
[http://dx.doi.org/10.1016/j.scp.2022.100927]
[61]
Vila, E.; Hornero-Méndez, D.; Lareo, C.; Saravia, V. Biotechnological production of zeaxanthin by an Antarctic Flavobacterium: Evaluation of culture conditions. J. Biotechnol., 2020, 319, 54-60.
[http://dx.doi.org/10.1016/j.jbiotec.2020.05.014] [PMID: 32450178]
[62]
De Bhowmick, G.; Sen, R.; Sarmah, A.K. Consolidated bioprocessing of wastewater cocktail in an algal biorefinery for enhanced biomass, lipid and lutein production coupled with efficient CO2 capture: An advanced optimization approach. J. Environ. Manage., 2019, 252, 109696.
[http://dx.doi.org/10.1016/j.jenvman.2019.109696] [PMID: 31629179]
[63]
Sampathkumar, S.J.; Gothandam, K.M. Sodium bicarbonate augmentation enhances lutein biosynthesis in green microalgae Chlorella pyrenoidosa. Biocatal. Agric. Biotechnol., 2019, 22, 101406.
[http://dx.doi.org/10.1016/j.bcab.2019.101406]
[64]
Schüler, L.M.; Santos, T.; Pereira, H.; Duarte, P.; Katkam, N.G.; Florindo, C.; Schulze, P.S.C.; Barreira, L.; Varela, J.C.S. Improved production of lutein and β-carotene by thermal and light intensity upshifts in the marine microalga Tetraselmis sp. CTP4. Algal Res., 2020, 45, 101732.
[http://dx.doi.org/10.1016/j.algal.2019.101732]
[65]
Shariati, S.; Zare, D.; Mirdamadi, S. Screening of carbon and nitrogen sources using mixture analysis designs for carotenoid production by Blakeslea trispora. Food Sci. Biotechnol., 2019, 28(2), 469-479.
[http://dx.doi.org/10.1007/s10068-018-0484-0] [PMID: 30956859]
[66]
Kanno, K.Y.F.; Karp, S.G.; Rodrigues, C.; de Andrade Tanobe, V.O.; Soccol, C.R.; da Costa Cardoso, L.A. Influence of organic solvents in the extraction and purification of torularhodin from Sporobolomyces ruberrimus. Biotechnol. Lett., 2021, 43(1), 89-98.
[http://dx.doi.org/10.1007/s10529-020-03023-8] [PMID: 33064227]
[67]
Mussagy, C.U.; Santos-Ebinuma, V.C.; Herculano, R.D.; Coutinho, J.A.P.; Pereira, J.F.B.; Pessoa, A. Ionic liquids or eutectic solvents? Identifying the best solvents for the extraction of astaxanthin and β-carotene from Phaffia rhodozyma yeast and preparation of biodegradable films. Green Chem., 2022, 24(1), 118-123.
[http://dx.doi.org/10.1039/D1GC03521E]
[68]
Slavin, J.L. Dietary fiber and body weight. Nutrition, 2005, 21(3), 411-418.
[http://dx.doi.org/10.1016/j.nut.2004.08.018] [PMID: 15797686]
[69]
Lattimer, J.M.; Haub, M.D. Effects of dietary fiber and its components on metabolic health. Nutrients, 2010, 2(12), 1266-1289.
[http://dx.doi.org/10.3390/nu2121266] [PMID: 22254008]
[70]
Mudgil, D. The interaction between insoluble and soluble fiber. In: Dietary Fiber for the Prevention of Cardiovascular Disease: Fiber’s Interaction between Gut Micoflora; Sugar Metabolism, Weight Control and Cardiovascular Health, 2017.
[http://dx.doi.org/10.1016/B978-0-12-805130-6.00003-3]
[71]
Whyte, J.L.; McArthur, R.; Topping, D.; Nestel, P. Oat bran lowers plasma cholesterol levels in mildly hypercholesterolemic men. J. Am. Diet. Assoc., 1992, 92(4), 446-449.
[http://dx.doi.org/10.1016/S0002-8223(21)00649-0] [PMID: 1313467]
[72]
Bell, S.; Goldman, V.M.; Bistrian, B.R.; Arnold, A.H.; Ostroff, G.; Forse, R.A. Effect of β-glucan from oats and yeast on serum lipids. Crit. Rev. Food Sci. Nutr., 1999, 39(2), 189-202.
[http://dx.doi.org/10.1080/10408399908500493] [PMID: 10198754]
[73]
Biörklund, M.; van Rees, A.; Mensink, R.P.; Önning, G. Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with β-glucans from oats or barley: A randomised dose-controlled trial. Eur. J. Clin. Nutr., 2005, 59(11), 1272-1281.
[http://dx.doi.org/10.1038/sj.ejcn.1602240] [PMID: 16015250]
[74]
Tappy, L. Regulation of hepatic glucose production in healthy subjects and patients with non-insulin-dependent diabetes mellitus. Diabete Metab., 1995, 21(4), 233-240.
[PMID: 8529757]
[75]
Rabbani, G.H.; Teka, T.; Zaman, B.; Majid, N.; Khatun, M.; Fuchs, G.J. Clinical studies in persistent diarrhea: Dietary management with green banana or pectin in Bangladeshi children. Gastroenterology, 2001, 121(3), 554-560.
[http://dx.doi.org/10.1053/gast.2001.27178] [PMID: 11522739]
[76]
Triplehorn, C.; Millard, P.S.; Triplehorn, C.; Millard, P.S. A rice-based diet with green banana or pectin reduced diarrhea in infants better than a rice-alone diet. ACP J. Club, 2002, 136(2), 67.
[http://dx.doi.org/10.7326/ACPJC-2002-136-2-067] [PMID: 11874292]
[77]
Olano-Martin, E.; Gibson, G.R.; Rastall, R.A. Comparison of the in vitro bifidogenic properties of pectins and pectic-oligosaccharides. J. Appl. Microbiol., 2002, 93(3), 505-511.
[http://dx.doi.org/10.1046/j.1365-2672.2002.01719.x] [PMID: 12174051]
[78]
Nangia-Makker, P.; Hogan, V.; Honjo, Y.; Baccarini, S.; Tait, L.; Bresalier, R.; Raz, A. Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin. J. Natl. Cancer Inst., 2002, 94(24), 1854-1862.
[http://dx.doi.org/10.1093/jnci/94.24.1854] [PMID: 12488479]
[79]
Lightowler, H.J.; Henry, C.J.K. Glycemic response of mashed potato containing high-viscocity hydroxypropylmethylcellulose. Nutr. Res., 2009, 29(8), 551-557.
[http://dx.doi.org/10.1016/j.nutres.2009.06.004] [PMID: 19761889]
[80]
Maki, K.C.; Davidson, M.H.; Witchger, M.S.; Dicklin, M.R.; Subbaiah, P.V. Effects of high-fiber oat and wheat cereals on postprandial glucose and lipid responses in healthy men. Int. J. Vitam. Nutr. Res., 2007, 77(5), 347-356.
[http://dx.doi.org/10.1024/0300-9831.77.5.347] [PMID: 18453320]
[81]
Gibson, G.R.; Beatty, E.R.; Wang, X.; Cummings, J.H. Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology, 1995, 108(4), 975-982.
[http://dx.doi.org/10.1016/0016-5085(95)90192-2] [PMID: 7698613]
[82]
Griffin, I.J.; Hicks, P.M.D.; Heaney, R.P.; Abrams, S.A. Enriched chicory inulin increases calcium absorption mainly in girls with lower calcium absorption. Nutr. Res., 2003, 23(7), 901-909.
[http://dx.doi.org/10.1016/S0271-5317(03)00085-X]
[83]
Cani, P.D.; Joly, E.; Horsmans, Y.; Delzenne, N.M. Oligofructose promotes satiety in healthy human: A pilot study. Eur. J. Clin. Nutr., 2006, 60(5), 567-572.
[http://dx.doi.org/10.1038/sj.ejcn.1602350] [PMID: 16340949]
[84]
Anderson, J.W.; Baird, P.; Davis, R.H., Jr; Ferreri, S.; Knudtson, M.; Koraym, A.; Waters, V.; Williams, C.L. Health benefits of dietary fiber. Nutr. Rev., 2009, 67(4), 188-205.
[http://dx.doi.org/10.1111/j.1753-4887.2009.00189.x] [PMID: 19335713]
[85]
Myhrstad, M.C.W.; Tunsjø, H.; Charnock, C.; Telle-Hansen, V.H. Dietary fiber, gut microbiota, and metabolic regulation—current status in human randomized trials. Nutrients, 2020, 12(3), 859.
[http://dx.doi.org/10.3390/nu12030859] [PMID: 32210176]
[86]
Brown, L.; Rosner, B.; Willett, W.W.; Sacks, F.M. Cholesterol-lowering effects of dietary fiber: A meta-analysis. Am. J. Clin. Nutr., 1999, 69(1), 30-42.
[http://dx.doi.org/10.1093/ajcn/69.1.30] [PMID: 9925120]
[87]
Livesey, G. Health potential of polyols as sugar replacers, with emphasis on low glycaemic properties. Nutr. Res. Rev., 2003, 16(2), 163-191.
[http://dx.doi.org/10.1079/NRR200371] [PMID: 19087388]
[88]
Yang, J.; Wang, H.P.; Zhou, L.; Xu, C.F. Effect of dietary fiber on constipation: A meta analysis. World J. Gastroenterol., 2012, 18(48), 7378-7383.
[http://dx.doi.org/10.3748/wjg.v18.i48.7378] [PMID: 23326148]
[89]
Flint, H.J.; Duncan, S.H.; Scott, K.P.; Louis, P. Links between diet, gut microbiota composition and gut metabolism. Proc. Nutr. Soc., 2015, 74(1), 13-22.
[http://dx.doi.org/10.1017/S0029665114001463] [PMID: 25268552]
[90]
Opie, R.S.; O’Neil, A.; Jacka, F.N.; Pizzinga, J.; Itsiopoulos, C. A modified Mediterranean dietary intervention for adults with major depression: Dietary protocol and feasibility data from the SMILES trial. Nutr. Neurosci., 2018, 21(7), 487-501.
[http://dx.doi.org/10.1080/1028415X.2017.1312841] [PMID: 28424045]
[91]
Halford, J.C.G.; Boyland, E.J.; Blundell, J.E.; Kirkham, T.C.; Harrold, J.A. Pharmacological management of appetite expression in obesity. Nat. Rev. Endocrinol., 2010, 6(5), 255-269.
[http://dx.doi.org/10.1038/nrendo.2010.19] [PMID: 20234354]
[92]
Dikeman, C.L.; Fahey, G.C., Jr Viscosity as related to dietary fiber: A review. Crit. Rev. Food Sci. Nutr., 2006, 46(8), 649-663.
[http://dx.doi.org/10.1080/10408390500511862] [PMID: 17092830]
[93]
Guillon, F.; Champ, M. Structural and physical properties of dietary fibres, and consequences of processing on human physiology. Food Res. Int., 2000, 33(3-4), 233-245.
[http://dx.doi.org/10.1016/S0963-9969(00)00038-7]
[94]
Ruiz-Gutiérrez, M.G.; Sánchez-Madrigal, M.Á.; Quintero-Ramos, A. The extrusion cooking process for the development of functional foods. In: In Extrusion of Metals, Polymers and Food Products; InTech, 2018.
[http://dx.doi.org/10.5772/intechopen.68741]
[95]
Roehrig, K.L. The physiological effects of dietary fiber—a review. Food Hydrocoll., 1988, 2(1), 1-18.
[http://dx.doi.org/10.1016/S0268-005X(88)80033-X]
[96]
Caprez, A.; Arrigoni, E.; Amadò, R.; Neukom, H. Influence of different types of thermal treatment on the chemical composition and physical properties of wheat bran. J. Cereal Sci., 1986, 4(3), 233-239.
[http://dx.doi.org/10.1016/S0733-5210(86)80025-X]
[97]
Elleuch, M.; Bedigian, D.; Roiseux, O.; Besbes, S.; Blecker, C.; Attia, H. Dietary fibre and fibre-rich by-products of food processing: Characterisation, technological functionality and commercial applications: A review. Food Chem., 2011, 124(2), 411-421.
[http://dx.doi.org/10.1016/j.foodchem.2010.06.077]
[98]
Wong, K.H.; Cheung, P.C.K. Dietary fibers from mushroom sclerotia: 1. Preparation and physicochemical and functional properties. J. Agric. Food Chem., 2005, 53(24), 9395-9400.
[http://dx.doi.org/10.1021/jf0510788] [PMID: 16302753]
[99]
Wong, K.H.; Cheung, P.C.K. Dietary fibers from mushroom Sclerotia: 2. In vitro mineral binding capacity under sequential simulated physiological conditions of the human gastrointestinal tract. J. Agric. Food Chem., 2005, 53(24), 9401-9406.
[http://dx.doi.org/10.1021/jf0510790] [PMID: 16302754]
[100]
Reinhold, J. Rickets in Asian immigrants. Lancet, 1976, 308(7995), 1132-1133.
[http://dx.doi.org/10.1016/S0140-6736(76)91104-1] [PMID: 62963]
[101]
Riedl, J.; Linseisen, J.; Hoffmann, J.; Wolfram, G. Some dietary fibers reduce the absorption of carotenoids in women. J. Nutr., 1999, 129(12), 2170-2176.
[http://dx.doi.org/10.1093/jn/129.12.2170] [PMID: 10573545]
[102]
Simopoulos, A. An increase in the omega-6/Omega-3 fatty acid ratio increases the risk for obesity. Nutrients, 2016, 8(3), 128.
[http://dx.doi.org/10.3390/nu8030128] [PMID: 26950145]
[103]
Mozaffarian, D.; Wu, J.H.Y. Omega-3 fatty acids and cardiovascular disease. J. Am. Coll. Cardiol., 2011, 58(20), 2047-2067.
[http://dx.doi.org/10.1016/j.jacc.2011.06.063] [PMID: 22051327]
[104]
Swanson, D.; Block, R.; Mousa, S.A. Omega-3 fatty acids EPA and DHA: health benefits throughout life. Adv. Nutr., 2012, 3(1), 1-7.
[http://dx.doi.org/10.3945/an.111.000893] [PMID: 22332096]
[105]
Calder, P.C. Omega-3 fatty acids and inflammatory processes. Nutrients, 2010, 2(3), 355-374.
[http://dx.doi.org/10.3390/nu2030355] [PMID: 22254027]
[106]
Kris-Etherton, P.M.; Harris, W.S.; Appel, L.J. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation, 2002, 106(21), 2747-2757.
[http://dx.doi.org/10.1161/01.CIR.0000038493.65177.94] [PMID: 12438303]
[107]
Avallone, R.; Vitale, G.; Bertolotti, M. Omega-3 fatty acids and neurodegenerative diseases: New evidence in clinical trials. Int. J. Mol. Sci., 2019, 20(17), 4256.
[http://dx.doi.org/10.3390/ijms20174256] [PMID: 31480294]
[108]
Shin, S.; Jing, K.; Jeong, S.; Kim, N.; Song, K.S.; Heo, J.Y.; Park, J.H.; Seo, K.S.; Han, J.; Park, J.I.; Kweon, G.R.; Park, S.K.; Wu, T.; Hwang, B.D.; Lim, K. The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53. BioMed Res. Int., 2013, 2013, 1-11.
[http://dx.doi.org/10.1155/2013/568671] [PMID: 23841076]
[109]
Burdge, G.C.; Calder, P.C. Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod. Nutr. Dev., 2005, 45(5), 581-597.
[http://dx.doi.org/10.1051/rnd:2005047] [PMID: 16188209]
[110]
Freitas, R.; Campos, M.M. Protective effects of omega-3 fatty acids in cancer-related complications. Nutrients, 2019, 11(5), 945.
[http://dx.doi.org/10.3390/nu11050945] [PMID: 31035457]
[111]
Roberfroid, M. Prebiotics: The concept revisited. J. Nutr., 2007, 137(3)(2), 830S-837S.
[http://dx.doi.org/10.1093/jn/137.3.830S] [PMID: 17311983]
[112]
Gibson, G.R.; Scott, K.P.; Rastall, R.A.; Tuohy, K.M.; Hotchkiss, A.; Dubert-Ferrandon, A.; Gareau, M.; Murphy, E.F.; Saulnier, D.; Loh, G.; Macfarlane, S.; Delzenne, N.; Ringel, Y.; Kozianowski, G.; Dickmann, R.; Lenoir-Wijnkoop, I.; Walker, C.; Buddington, R. Dietary prebiotics: Current status and new definition. Food Sci. Technol. Bull., 2010, 7(1), 1-19.
[http://dx.doi.org/10.1616/1476-2137.15880]
[113]
Slavin, J. Fiber and prebiotics: Mechanisms and health benefits. Nutrients, 2013, 5(4), 1417-1435.
[http://dx.doi.org/10.3390/nu5041417] [PMID: 23609775]
[114]
Gibson, G.R.; Hutkins, R.; Sanders, M.E.; Prescott, S.L.; Reimer, R.A.; Salminen, S.J.; Scott, K.; Stanton, C.; Swanson, K.S.; Cani, P.D.; Verbeke, K.; Reid, G. Expert consensus document: The international scientific association for probiotics and prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat. Rev. Gastroenterol. Hepatol., 2017, 14(8), 491-502.
[http://dx.doi.org/10.1038/nrgastro.2017.75] [PMID: 28611480]
[115]
Delzenne, N.M.; Cani, P.D.; Daubioul, C.; Neyrinck, A.M. Impact of inulin and oligofructose on gastrointestinal peptides. Br. J. Nutr., 2005, 93(S1)(Suppl. 1), S157-S161.
[http://dx.doi.org/10.1079/BJN20041342] [PMID: 15877889]
[116]
Bindels, L.B.; Delzenne, N.M.; Cani, P.D.; Walter, J. Towards a more comprehensive concept for prebiotics. Nat. Rev. Gastroenterol. Hepatol., 2015, 12(5), 303-310.
[http://dx.doi.org/10.1038/nrgastro.2015.47] [PMID: 25824997]
[117]
Tuohy, K.M.; Kolida, S.; Lustenberger, A.M.; Gibson, G.R. The prebiotic effects of biscuits containing partially hydrolysed guar gum and fructo-oligosaccharides: A human volunteer study. Br. J. Nutr., 2001, 86(3), 341-348.
[http://dx.doi.org/10.1079/BJN2001394] [PMID: 11570986]
[118]
Langkamp-Henken, B.; Wood, S.M.; Herlinger-Garcia, K.A.; Thomas, D.J.; Stechmiller, J.K.; Bender, B.S.; Gardner, E.M.; DeMichele, S.J.; Schaller, J.P.; Murasko, D.M. Nutritional formula improved immune profiles of seniors living in nursing homes. J. Am. Geriatr. Soc., 2006, 54(12), 1861-1870.
[http://dx.doi.org/10.1111/j.1532-5415.2006.00982.x] [PMID: 17198491]
[119]
Guess, N.D.; Dornhorst, A.; Oliver, N.; Bell, J.D.; Thomas, E.L.; Frost, G.S. A randomized controlled trial: The effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutr. Metab., 2015, 12(1), 36.
[http://dx.doi.org/10.1186/s12986-015-0033-2] [PMID: 26500686]
[120]
Hill, C.; Guarner, F.; Reid, G.; Gibson, G.R.; Merenstein, D.J.; Pot, B.; Morelli, L.; Canani, R.B.; Flint, H.J.; Salminen, S.; Calder, P.C.; Sanders, M.E. The international scientific association for probiotics and prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat. Rev. Gastroenterol. Hepatol., 2014, 11(8), 506-514.
[http://dx.doi.org/10.1038/nrgastro.2014.66] [PMID: 24912386]
[121]
Sanders, M.E. Probiotics: Definition, sources, selection, and uses. Clin. Infect. Dis., 2008, 46(2), 58-61.
[http://dx.doi.org/10.1086/523341]
[122]
Plaza-Diaz, J.; Ruiz-Ojeda, F.J.; Gil-Campos, M.; Gil, A. Mechanisms of action of probiotics. Adv. Nutr., 2019, 10(1), S49-S66.
[http://dx.doi.org/10.1093/advances/nmy063] [PMID: 30721959]
[123]
Hemarajata, P.; Versalovic, J. Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Therap. Adv. Gastroenterol., 2013, 6(1), 39-51.
[http://dx.doi.org/10.1177/1756283X12459294] [PMID: 23320049]
[124]
Kobyliak, N.; Falalyeyeva, T.; Boyko, N.; Tsyryuk, O.; Beregova, T.; Ostapchenko, L. Probiotics and nutraceuticals as a new frontier in obesity prevention and management. Diabetes Res. Clin. Pract., 2018, 141, 190-199.
[http://dx.doi.org/10.1016/j.diabres.2018.05.005] [PMID: 29772287]
[125]
Rahman, M.M.; Islam, F. -Or-Rashid, M.H.; Mamun, A.A.; Rahaman, M.S.; Islam, M.M.; Meem, A.F.K.; Sutradhar, P.R.; Mitra, S.; Mimi, A.A.; Emran, T.B.; Fatimawali; Idroes, R.; Tallei, T.E.; Ahmed, M.; Cavalu, S. The gut microbiota (Microbiome) in cardiovascular disease and its therapeutic regulation. Front. Cell. Infect. Microbiol., 2022, 12, 903570.
[http://dx.doi.org/10.3389/fcimb.2022.903570] [PMID: 35795187]
[126]
Marco, M.L.; Heeney, D.; Binda, S.; Cifelli, C.J.; Cotter, P.D.; Foligné, B.; Gänzle, M.; Kort, R.; Pasin, G.; Pihlanto, A.; Smid, E.J.; Hutkins, R. Health benefits of fermented foods: Microbiota and beyond. Curr. Opin. Biotechnol., 2017, 44, 94-102.
[http://dx.doi.org/10.1016/j.copbio.2016.11.010] [PMID: 27998788]
[127]
Dong, H.; Rowland, I.; Yaqoob, P. Comparative effects of six probiotic strains on immune function in vitro. Br. J. Nutr., 2012, 108(3), 459-470.
[http://dx.doi.org/10.1017/S0007114511005824] [PMID: 22054064]
[128]
Ejtahed, H.S.; Mohtadi-Nia, J.; Homayouni-Rad, A.; Niafar, M.; Asghari-Jafarabadi, M.; Mofid, V. Probiotic yogurt improves antioxidant status in type 2 diabetic patients. Nutrition, 2012, 28(5), 539-543.
[http://dx.doi.org/10.1016/j.nut.2011.08.013] [PMID: 22129852]
[129]
Aloğlu, H.; Öner, Z. Assimilation of cholesterol in broth, cream, and butter by probiotic bacteria. Eur. J. Lipid Sci. Technol., 2006, 108(9), 709-713.
[http://dx.doi.org/10.1002/ejlt.200600137]
[130]
Ekinci, F.Y.; Okur, O.D.; Ertekin, B.; Guzel-Seydim, Z. Effects of probiotic bacteria and oils on fatty acid profiles of cultured cream. Eur. J. Lipid Sci. Technol., 2008, 110(3), 216-224.
[http://dx.doi.org/10.1002/ejlt.200700038]
[131]
Goudarzi, M.; Goudarzi, H.; Rashidan, M. Probiotics: An update on mechanisms of action and clinical applications. Nov. Biomed., 2014, 2(1)
[132]
Hemaiswarya, S.; Raja, R.; Ravikumar, R.; Carvalho, I.S. Mechanism of action of probiotics. Braz. Arch. Biol. Technol., 2013, 56(1), 113-119.
[http://dx.doi.org/10.1590/S1516-89132013000100015]
[133]
Saulnier, D.M.A.; Spinler, J.K.; Gibson, G.R.; Versalovic, J. Mechanisms of probiosis and prebiosis: Considerations for enhanced functional foods. Curr. Opin. Biotechnol., 2009, 20(2), 135-141.
[http://dx.doi.org/10.1016/j.copbio.2009.01.002] [PMID: 19243931]
[134]
Ng, S.C.; Hart, A.L.; Kamm, M.A.; Stagg, A.J.; Knight, S.C. Mechanisms of action of probiotics: Recent advances. Inflamm. Bowel Dis., 2009, 15(2), 300-310.
[http://dx.doi.org/10.1002/ibd.20602] [PMID: 18626975]
[135]
Rimm, E.B.; Appel, L.J.; Chiuve, S.E.; Djoussé, L.; Engler, M.B.; Kris-Etherton, P.M.; Mozaffarian, D.; Siscovick, D.S.; Lichtenstein, A.H. Seafood long-chain n-3 polyunsaturated fatty acids and cardiovascular disease: A science advisory from the american heart association. Circulation, 2018, 138(1), e35-e47.
[http://dx.doi.org/10.1161/CIR.0000000000000574] [PMID: 29773586]
[136]
Kris-Etherton, P.M.; Hecker, K.D.; Bonanome, A.; Coval, S.M.; Binkoski, A.E.; Hilpert, K.F.; Griel, A.E.; Etherton, T.D. Bioactive compounds in foods: Their role in the prevention of cardiovascular disease and cancer. Am. J. Med., 2002, 113(9), 71-88.
[http://dx.doi.org/10.1016/S0002-9343(01)00995-0]
[137]
González, C.A.; Pera, G.; Agudo, A.; Bueno-de-Mesquita, H.B.; Ceroti, M.; Boeing, H.; Schulz, M.; Del Giudice, G.; Plebani, M.; Carneiro, F.; Berrino, F.; Sacerdote, C.; Tumino, R.; Panico, S.; Berglund, G.; Simán, H.; Hallmans, G.; Stenling, R.; Martinez, C.; Dorronsoro, M.; Barricarte, A.; Navarro, C.; Quiros, J.R.; Allen, N.; Key, T.J.; Bingham, S.; Day, N.E.; Linseisen, J.; Nagel, G.; Overvad, K.; Jensen, M.K.; Olsen, A.; Tjønneland, A.; Büchner, F.L.; Peeters, P.H.M.; Numans, M.E.; Clavel-Chapelon, F.; Boutron-Ruault, M.C.; Roukos, D.; Trichopoulou, A.; Psaltopoulou, T.; Lund, E.; Casagrande, C.; Slimani, N.; Jenab, M.; Riboli, E. Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the european prospective investigation into cancer and nutrition (EPIC–EURGAST). Int. J. Cancer, 2006, 118(10), 2559-2566.
[http://dx.doi.org/10.1002/ijc.21678] [PMID: 16380980]
[138]
Liu, J.; Xing, J.; Fei, Y. Green tea (Camellia sinensis) and cancer prevention: A systematic review of randomized trials and epidemiological studies. Chin. Med., 2008, 3(1), 12.
[http://dx.doi.org/10.1186/1749-8546-3-12] [PMID: 18940008]
[139]
Jenkins, D.J.A.; Kendall, C.W.C.; Augustin, L.S.A.; Mitchell, S.; Sahye-Pudaruth, S.; Blanco Mejia, S.; Chiavaroli, L.; Mirrahimi, A.; Ireland, C.; Bashyam, B.; Vidgen, E.; de Souza, R.J.; Sievenpiper, J.L.; Coveney, J.; Leiter, L.A.; Josse, R.G. Effect of legumes as part of a low glycemic index diet on glycemic control and cardiovascular risk factors in type 2 diabetes mellitus: a randomized controlled trial. Arch. Intern. Med., 2012, 172(21), 1653-1660.
[http://dx.doi.org/10.1001/2013.jamainternmed.70] [PMID: 23089999]
[140]
Qin, B.; Panickar, K.S.; Anderson, R.A. Cinnamon: Potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes. J. Diabetes Sci. Technol., 2010, 4(3), 685-693.
[http://dx.doi.org/10.1177/193229681000400324] [PMID: 20513336]
[141]
Baer, D.J.; Dalton, M.; Blundell, J.; Finlayson, G.; Hu, F.B. Nuts, energy balance and body weight. Nutrients, 2023, 15(5), 1162.
[http://dx.doi.org/10.3390/nu15051162] [PMID: 36904160]
[142]
Rebello, C.J.; Johnson, W.D.; Martin, C.K.; Xie, W.; O’Shea, M.; Kurilich, A.; Bordenave, N.; Andler, S.; Klinken, B.J.W.; Chu, Y.F.; Greenway, F.L. Acute effect of oatmeal on subjective measures of appetite and satiety compared to a ready-to-eat breakfast cereal: A randomized crossover trial. J. Am. Coll. Nutr., 2013, 32(4), 272-279.
[http://dx.doi.org/10.1080/07315724.2013.816614] [PMID: 24024772]
[143]
Hasler, C.M. Functional foods: Benefits, concerns and challenges-a position paper from the american council on science and health. J. Nutr., 2002, 132(12), 3772-3781.
[http://dx.doi.org/10.1093/jn/132.12.3772] [PMID: 12468622]
[144]
Murphy, S.P. Nutrition guidelines to maintain health. In: In Nutrition in the Prevention and Treatment of Disease; , 2001; p. 753-771.
[http://dx.doi.org/10.1016/B978-012193155-1/50050-7]
[145]
Katan, M.B. Health claims for functional foods. BMJ, 2004, 328(7433), 180-181.
[http://dx.doi.org/10.1136/bmj.328.7433.180] [PMID: 14739167]
[146]
Domínguez Díaz, L.; Fernández-Ruiz, V.; Cámara, M. An international regulatory review of food health-related claims in functional food products labeling. J. Funct. Foods, 2020, 68(103896), 103896.
[http://dx.doi.org/10.1016/j.jff.2020.103896]
[147]
Butler, D. Global challenges. Water. Glob. Chall., 2017, 1(1), 61-62.
[http://dx.doi.org/10.1002/gch2.1002] [PMID: 31565259]
[148]
Heasman, M.; Mellentin, J. The Functional Foods Revolution: Healthy People; Healthy Profits: London, 2014.
[http://dx.doi.org/10.4324/9781849776165]
[149]
Bröring, S.; Martin Cloutier, L.; Leker, J. The front end of innovation in an era of industry convergence: evidence from nutraceuticals and functional foods. R & D Manag., 2006, 36(5), 487-498.
[http://dx.doi.org/10.1111/j.1467-9310.2006.00449.x]
[150]
Diestre, L.; Rajagopalan, N. Are all ‘sharks’ dangerous? new biotechnology ventures and partner selection in R&D alliances. Strateg. Manage. J., 2012, 33(10), 1115-1134.
[http://dx.doi.org/10.1002/smj.1978]
[151]
Nieto, M.J.; Santamaría, L. The importance of diverse collaborative networks for the novelty of product innovation. Technovation, 2007, 27(6-7), 367-377.
[http://dx.doi.org/10.1016/j.technovation.2006.10.001]
[152]
Tether, B.S. Who co-operates for innovation, and why. Res. Policy, 2002, 31(6), 947-967.
[http://dx.doi.org/10.1016/S0048-7333(01)00172-X]
[153]
Sadler, J. Innovation in Functional Food and Drinks; Consumer, 2005.
[154]
Mortara, L.; Minshall, T. How do large multinational companies implement open innovation? Technovation, 2011, 31(10-11), 586-597.
[http://dx.doi.org/10.1016/j.technovation.2011.05.002]
[155]
Siedlok, F.; Smart, P.; Gupta, A. Convergence and reorientation via open innovation: The emergence of nutraceuticals. Technol. Anal. Strateg. Manage., 2010, 22(5), 571-592.
[http://dx.doi.org/10.1080/09537325.2010.488062]
[156]
Ronteltap, A.; van Trijp, J.C.M.; Renes, R.J.; Frewer, L.J. Consumer acceptance of technology-based food innovations: Lessons for the future of nutrigenomics. Appetite, 2007, 49(1), 1-17.
[http://dx.doi.org/10.1016/j.appet.2007.02.002] [PMID: 17382433]
[157]
Matthyssens, P.; Vandenbempt, K.; Berghman, L. Value innovation in the functional foods industry. Br. Food J., 2008, 110(1), 144-155.
[http://dx.doi.org/10.1108/00070700810844830]
[158]
Kotilainen, L.; Rajalahti, R.; Ragasa, C.; Pehu, E. Health Enhancing Foods: Opportunities for Strengthening the Sector in Developing Countries; Processing, 2006.
[http://dx.doi.org/10.3109/15563657809150015]
[159]
Mark-Herbert, C. Innovation of a new product category: Functional foods. Technovation, 2004, 24(9), 713-719.
[http://dx.doi.org/10.1016/S0166-4972(02)00131-1]
[160]
van Kleef, E.; van Trijp, H.C.M.; Luning, P. Functional foods: Health claim-food product compatibility and the impact of health claim framing on consumer evaluation. Appetite, 2005, 44(3), 299-308.
[http://dx.doi.org/10.1016/j.appet.2005.01.009] [PMID: 15894404]
[161]
Menrad, K. Market and marketing of functional food in Europe. J. Food Eng., 2003, 56(2-3), 181-188.
[http://dx.doi.org/10.1016/S0260-8774(02)00247-9]
[162]
Bech-Larsen, T.; Scholderer, J. Functional foods in Europe: Consumer research, market experiences and regulatory aspects. Trends Food Sci. Technol., 2007, 18(4), 231-234.
[http://dx.doi.org/10.1016/j.tifs.2006.12.006]
[163]
Urala, N.; Lähteenmäki, L. Consumers’ changing attitudes towards functional foods. Food Qual. Prefer., 2007, 18(1), 1-12.
[http://dx.doi.org/10.1016/j.foodqual.2005.06.007]
[164]
Probiotics market size, share & trends analysis report by product (probiotic food & beverages, probiotic dietary supplements), by ingredient (Bacteria, Yeast), by end use, by distribution channel, and segment forecasts. Available from: https://www.researchandmarkets.com/reports/3972861/probiotics-market-size-share-and-trends-analysis (Accessed 2023-08-08).
[165]
Plasek, B.; Temesi, Á. The credibility of the effects of functional food products and consumers’ willingness to purchase/willingness to pay– review. Appetite, 2019, 143(104398), 104398.
[http://dx.doi.org/10.1016/j.appet.2019.104398] [PMID: 31401236]
[166]
Santeramo, F.G.; Carlucci, D.; De Devitiis, B.; Seccia, A.; Stasi, A.; Viscecchia, R.; Nardone, G. Emerging trends in European food, diets and food industry. Food Res. Int., 2018, 104, 39-47.
[http://dx.doi.org/10.1016/j.foodres.2017.10.039] [PMID: 29433781]
[167]
Bleiel, J. Functional foods from the perspective of the consumer: How to make it a success? Int. Dairy J., 2010, 20(4), 303-306.
[http://dx.doi.org/10.1016/j.idairyj.2009.11.009]
[168]
Ten Key Trends in Food. Ten key trends in food, Nutrition & Health 2008. Nutr. Food Sci., 2008, 38(3), nfs.2008.01738cab.036.
[http://dx.doi.org/10.1108/nfs.2008.01738cab.036]
[169]
Arvanitoyannis, I.S.; Van Houwelingen-Koukaliaroglou, M. Functional foods: A survey of health claims, pros and cons, and current legislation. Crit. Rev. Food Sci. Nutr., 2005, 45(5), 385-404.
[http://dx.doi.org/10.1080/10408390590967667] [PMID: 16130415]
[170]
Verbeke, W.; Sioen, I.; Pieniak, Z.; Van Camp, J.; De Henauw, S. Consumer perception versus scientific evidence about health benefits and safety risks from fish consumption. Public Health Nutr., 2005, 8(4), 422-429.
[http://dx.doi.org/10.1079/PHN2004697] [PMID: 15975189]
[171]
Christidis, N.; Tsoulfa, G.; Varagunam, M.; Babatzimopoulou, M. A cross sectional study of consumer awareness of functional foods in Thessaloniki, Greece. Nutr. Food Sci., 2011, 41(3), 165-174.
[http://dx.doi.org/10.1108/00346651111132439]
[172]
Grunert, K.G.; Scholderer, J.; Rogeaux, M. Determinants of consumer understanding of health claims. Appetite, 2011, 56(2), 269-277.
[http://dx.doi.org/10.1016/j.appet.2011.01.009] [PMID: 21238525]
[173]
Baker, M.T.; Lu, P.; Parrella, J.A.; Leggette, H.R. Consumer acceptance toward functional foods: A scoping review. Int. J. Environ. Res. Public Health, 2022, 19(3), 1217.
[http://dx.doi.org/10.3390/ijerph19031217] [PMID: 35162240]
[174]
Bublitz, M.G.; Peracchio, L.A.; Block, L.G. Why did I eat that? Perspectives on food decision making and dietary restraint. J. Consum. Psychol., 2010, 20(3), 239-258.
[http://dx.doi.org/10.1016/j.jcps.2010.06.008]
[175]
Kraak, V.I.; Story, M.; Wartella, E.A.; Ginter, J. Industry progress to market a healthful diet to American children and adolescents. Am. J. Prev. Med., 2011, 41(3), 322-333.
[http://dx.doi.org/10.1016/j.amepre.2011.05.029] [PMID: 21855748]
[176]
Celis-Morales, C.; Livingstone, K.M.; Marsaux, C.F.M.; Macready, A.L.; Fallaize, R.; O’Donovan, C.B.; Woolhead, C.; Forster, H.; Walsh, M.C.; Navas-Carretero, S.; San-Cristobal, R.; Tsirigoti, L.; Lambrinou, C.P.; Mavrogianni, C.; Moschonis, G.; Kolossa, S.; Hallmann, J.; Godlewska, M. Surwiłło, A.; Traczyk, I.; Drevon, C.A.; Bouwman, J.; van Ommen, B.; Grimaldi, K.; Parnell, L.D.; Matthews, J.N.S.; Manios, Y.; Daniel, H.; Martinez, J.A.; Lovegrove, J.A.; Gibney, E.R.; Brennan, L.; Saris, W.H.M.; Gibney, M.; Mathers, J.C. Effect of personalized nutrition on health-related behaviour change: Evidence from the Food4me European randomized controlled trial. Int. J. Epidemiol., 2016, 46(2), dyw186.
[http://dx.doi.org/10.1093/ije/dyw186] [PMID: 27524815]
[177]
Fenech, M.; El-Sohemy, A.; Cahill, L.; Ferguson, L.R.; French, T.A.C.; Tai, E.S.; Milner, J.; Koh, W.P.; Xie, L.; Zucker, M.; Buckley, M.; Cosgrove, L.; Lockett, T.; Fung, K.Y.C.; Head, R. Nutrigenetics and nutrigenomics: Viewpoints on the current status and applications in nutrition research and practice. Lifestyle Genomics, 2011, 4(2), 69-89.
[http://dx.doi.org/10.1159/000327772] [PMID: 21625170]
[178]
Tuso, P.J.; Ismail, M.H.; Ha, B.P.; Bartolotto, C. Nutritional update for physicians: Plant-based diets. Perm. J., 2013, 17(2), 61-66.
[http://dx.doi.org/10.7812/TPP/12-085] [PMID: 23704846]
[179]
Satija, A.; Bhupathiraju, S.N.; Rimm, E.B.; Spiegelman, D.; Chiuve, S.E.; Borgi, L.; Willett, W.C.; Manson, J.E.; Sun, Q.; Hu, F.B. Plant-based dietary patterns and incidence of type 2 diabetes in us men and women: Results from three prospective cohort studies. PLoS Med., 2016, 13(6), e1002039.
[http://dx.doi.org/10.1371/journal.pmed.1002039] [PMID: 27299701]
[180]
Holscher, H.D.; Caporaso, J.G.; Hooda, S.; Brulc, J.M.; Fahey, G.C., Jr; Swanson, K.S. Fiber supplementation influences phylogenetic structure and functional capacity of the human intestinal microbiome: Follow-up of a randomized controlled trial. Am. J. Clin. Nutr., 2015, 101(1), 55-64.
[http://dx.doi.org/10.3945/ajcn.114.092064] [PMID: 25527750]
[181]
Ferguson, L.R. Nutrigenomics. Mol. Diagn. Ther., 2006, 10(2), 101-108.
[http://dx.doi.org/10.1007/BF03256449] [PMID: 16669608]
[182]
Fogg-Johnson, N. Merolli, A. Nutrigenomics: The next Wave in Nutrition Research; Nutraceuticals World, 2000, p. 3.
[183]
Craig Venter, J.; Adams, M.D.; Myers, E.W.; Li, P.W. The sequence of the human genome. Science, 291, 5507.
[http://dx.doi.org/10.1126/science.1058040]
[184]
Gura, T. New genes boost rice nutrients. Science, 1999, 285, 5430.
[http://dx.doi.org/10.1126/science.285.5430.994]
[185]
IFT expert report on biotechnology and foods. Food Technol., 2000, 54(8)
[186]
Falk, M.C.; Chassy, B.M.; Harlander, S.K.; Hoban, T.J.; Mcgloughlin, M.N.; Akhlaghi, A.R. Issues and opinions food biotechnology: Benefits and concerns. J. Nutr., 2002, 132(April)
[187]
Ravera, A.; Carubelli, V.; Sciatti, E.; Bonadei, I.; Gorga, E.; Cani, D.; Vizzardi, E.; Metra, M.; Lombardi, C. Nutrition and cardiovascular disease: Finding the perfect recipe for cardiovascular health. Nutrients, 2016, 8(6), 363.
[http://dx.doi.org/10.3390/nu8060363] [PMID: 27314382]
[188]
Andreani, G.; Sogari, G.; Marti, A.; Froldi, F.; Dagevos, H.; Martini, D. Plant-based meat alternatives: Technological, nutritional, environmental, market, and social challenges and opportunities. Nutrients, 2023, 15(2), 452.
[http://dx.doi.org/10.3390/nu15020452] [PMID: 36678323]
[189]
Cheung, R.; Ng, T.; Wong, J. Marine peptides: Bioactivities and applications. Mar. Drugs, 2015, 13(7), 4006-4043.
[http://dx.doi.org/10.3390/md13074006] [PMID: 26132844]
[190]
Orkusz, A. Edible insects versus meat—nutritional comparison: knowledge of their composition is the key to good health. Nutrients, 2021, 13(4), 1207.
[http://dx.doi.org/10.3390/nu13041207] [PMID: 33917531]
[191]
Lynch, H.; Johnston, C.; Wharton, C. Plant-based diets: Considerations for environmental impact, protein quality, and exercise performance. Nutrients, 2018, 10(12), 1841.
[http://dx.doi.org/10.3390/nu10121841] [PMID: 30513704]
[192]
Demestichas, K.; Peppes, N.; Alexakis, T.; Adamopoulou, E. Blockchain in agriculture traceability systems: A review. Appl. Sci., 2020, 10(12), 4113.
[http://dx.doi.org/10.3390/app10124113]

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