1,3-Thiazole Derivatives as a Promising Scaffold in Medicinal Chemistry:
A Recent Overview

Pragati      Kushwaha; Shashi      Pandey
doi:10.2174/0118715230276678231102150158
Abstract

The thiazole ring is a unique heterocyclic motif among heterocyclic compounds. This five-member ring with one nitrogen and one sulphur atom displays a wide array of pharmacological activities, including anti-inflammatory, antimicrobial, anticancer, antidiabetic, antiviral, etc., by acting on several targets. Its broad range of medical applications has inspired us to study this opulent heterocyclic molecule. The current review summarizes synthetic approaches for the preparation of thiazole derivatives in brief and discusses the promising biological activities of this scaffold. This review will be useful to the drug discovery community and will facilitate the synthesis and development of novel and potent thiazole derivatives, which may serve as lead molecules for the treatment of various diseases.
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DOI https://dx.doi.org/10.2174/0118715230276678231102150158	Print ISSN 1871-5230
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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

1,3-Thiazole Derivatives as a Promising Scaffold in Medicinal Chemistry: A Recent Overview

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