Abstract
Purpose: This study aims to compare chest computed tomography (CT) findings between adult and pediatric patients with coronavirus disease-19 (COVID-19) pneumonia.
Materials and Methods: This study included 30 pediatric patients aged 1 to 17 years and 30 adult patients over 18 years of age with COVID-19 pneumonia confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR) who have findings related to COVID-19 on Chest Computed Tomography. The CT findings of adult and pediatric patients were compared with a z-test.
Results: Bilateral involvement (p:0.00056), involvement in all five lobes (p<0.00001), and central and peripheral involvement (p:0.01928) were significantly higher in the adult group compared to the pediatric group. In the pediatric group, the frequency of unilateral involvement (p:0.00056), involvement of solitary lobe (p:0.00132), and peripheral involvement (p: 0.01928) were significantly higher than in the adult group. The most common parenchymal finding in adults and pediatric patients was ground-glass opacities (100% and 83%, respectively). Among the parenchymal findings in adults, ground-glass opacities with consolidation (63%) were the second most common finding, followed by air bronchogram (60%) in adults, while in pediatric patients, halo sign (27%) and nodule (27%) were the second most common, followed by the ground-glass opacities with consolidation (23%).
Conclusion: The CT findings of pediatric COVID-19 patients must be well-known as the course of the disease is usually less severe, and the radiological findings are uncertain when compared with adults.
[http://dx.doi.org/10.1016/S0140-6736(20)30183-5] [PMID: 31986264]
[http://dx.doi.org/10.1089/ped.2020.1166] [PMID: 35921580]
[http://dx.doi.org/10.1007/s00431-020-03684-7] [PMID: 32424745]
[http://dx.doi.org/10.1259/bjr.20200647] [PMID: 32730110]
[http://dx.doi.org/10.2214/AJR.20.23145] [PMID: 32442030]
[http://dx.doi.org/10.1016/j.clinimag.2020.11.022] [PMID: 33197713]
[http://dx.doi.org/10.1016/j.diii.2020.03.014] [PMID: 32291197]
[http://dx.doi.org/10.1148/radiol.2020201343] [PMID: 32301646]
[http://dx.doi.org/10.1148/radiol.2020200463] [PMID: 32077789]
[http://dx.doi.org/10.1007/s00330-020-06865-y] [PMID: 32314058]
[http://dx.doi.org/10.1148/rg.2020200159] [PMID: 33095680]
[http://dx.doi.org/10.1038/s41390-020-1015-2] [PMID: 32555539]
[http://dx.doi.org/10.1155/2020/1023506]
[http://dx.doi.org/10.1093/tropej/fmaa045] [PMID: 32692815]
[http://dx.doi.org/10.1016/j.jacr.2020.03.006] [PMID: 32283052]
[http://dx.doi.org/10.1186/s43055-020-00261-8]
[http://dx.doi.org/10.5114/pjr.2021.102609]
[http://dx.doi.org/10.1007/s00330-020-06860-3] [PMID: 32291501]
[http://dx.doi.org/10.1002/jmv.26398] [PMID: 32761898]
[http://dx.doi.org/10.4103/ejop.ejop_41_20]
[http://dx.doi.org/10.1002/ppul.24718] [PMID: 32134205]
[http://dx.doi.org/10.2214/AJR.20.22975] [PMID: 32134681]
[http://dx.doi.org/10.1136/thx.2010.139360] [PMID: 20820062]
[http://dx.doi.org/10.21037/tp-20-281] [PMID: 33633932]
[http://dx.doi.org/10.1016/j.ejrad.2020.108972] [PMID: 32240913]
[http://dx.doi.org/10.1002/ppul.25070] [PMID: 32926572]
[http://dx.doi.org/10.1016/j.jcv.2020.104353] [PMID: 32302953]
[http://dx.doi.org/10.1016/j.clinimag.2020.10.035] [PMID: 33142125]
[http://dx.doi.org/10.21037/atm-20-4955] [PMID: 32793722]
[http://dx.doi.org/10.1007/s00284-021-02413-z] [PMID: 33847795]
[http://dx.doi.org/10.1016/j.acra.2020.07.031] [PMID: 32773328]
[http://dx.doi.org/10.1148/ryct.2020200034]
[http://dx.doi.org/10.1007/s11547-020-01237-4] [PMID: 32500509]
[http://dx.doi.org/10.1007/s00259-020-04735-9] [PMID: 32107577]
[http://dx.doi.org/10.1186/s12887-020-02140-7]
[http://dx.doi.org/10.1080/23744235.2021.1924397] [PMID: 34024217]