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Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Rare and First Manifestation of Lupus Panniculitis as Lupus Mastitis: A Case Report and Literature Review

Author(s): Chong Yong Guo, Li Chen, Lin Sun, Xiao Shan Yang, Ruiqi Mao, Bo Cheng Li, Xin Jun Li and Ling Zhou*

Volume 20, 2024

Published on: 14 September, 2023

Article ID: e040823219416 Pages: 5

DOI: 10.2174/1573405620666230804092737

Price: $65

Abstract

Introduction: This case report presents a rare occurrence of lupus mastitis affecting the breast.

Case Presentation: An induration with mild discomfort was detected in the upper inner quadrant of the right breast of a 27-year-old Chinese woman with regular menstrual cycles. The patient is currently unmarried and has no previous history of full-term pregnancies or lactation. An ill-defined, subcutaneous, hyperechoic lesion with no calcification was visualized on breast ultrasound. Peripheral and internal blood flow signals demonstrated high intensity. Pathological analysis of a breast needle biopsy revealed fat lobule necrosis accompanied by mixed lymphoplasmacytic and histiocytic aggregates.

Conclusion: The diagnosis of lupus mastitis necessitates a comprehensive evaluation of the patient's medical history, serological testing, imaging studies, and histopathological analysis.

[1]
Martella S, Matthes AGZ, Bassi F, et al. Lupus mastitis in male mimicking a breast lump. Int J Surg 2008; 6(6): e67-9.
[http://dx.doi.org/10.1016/j.ijsu.2007.02.009] [PMID: 17462967]
[2]
Summers TA Jr, Lehman MB, Barner R, Royer MC. Lupus mastitis. Adv Anat Pathol 2009; 16(1): 56-61.
[http://dx.doi.org/10.1097/PAP.0b013e3181915ff7] [PMID: 19098467]
[3]
Mosier AD, Boldt B, Keylock J, Smith DV, Graham J. Serial MR findings and comprehensive review of bilateral lupus mastitis with an additional case report. J Radiol Case Rep 2013; 7(1): 48-58.
[http://dx.doi.org/10.3941/jrcr.v7i1.1242] [PMID: 23372875]
[4]
Rosa M, Mohammadi A. Lupus mastitis: A review. Ann Diagn Pathol 2013; 17(2): 230-3.
[http://dx.doi.org/10.1016/j.anndiagpath.2012.09.003] [PMID: 23190681]
[5]
Petri M. Epidemiology of systemic lupus erythematosus. Best Pract Res Clin Rheumatol 2002; 16(5): 847-58.
[http://dx.doi.org/10.1053/berh.2002.0259] [PMID: 12473278]
[6]
Voizard B, Lalonde L, Sanchez LM, et al. Lupus mastitis as a first manifestation of systemic disease: About two cases with a review of the literature. Eur J Radiol 2017; 92: 124-31.
[http://dx.doi.org/10.1016/j.ejrad.2017.04.023] [PMID: 28624010]
[7]
Vineetha M, Palakkal S, Sobhanakumari K, Celine MI. Interchanging autoimmunity - lupus mastitis coexisting with systemic polyarteritis nodosa. Indian J Dermatol 2016; 61(2): 200-2.
[http://dx.doi.org/10.4103/0019-5154.177759] [PMID: 27057023]
[8]
Tanaka Y, Manabe H, Shinzaki W, Hashimoto Y, Komoike Y. A case of lupus mastitis in a patient with systemic lupus erythematosus. Breast J 2020; 26(4): 780-1.
[http://dx.doi.org/10.1111/tbj.13582] [PMID: 31538694]
[9]
Cernea SS, Kihara SM, Sotto MN, Vilela MAC. Lupus mastitis. J Am Acad Dermatol 1993; 29(2): 343-6.
[http://dx.doi.org/10.1016/0190-9622(93)70192-V] [PMID: 8340511]
[10]
Holland NW, McKnight K, Challa VR, Agudelo CA. Lupus panniculitis (profundus) involving the breast: Report of 2 cases and review of the literature. J Rheumatol 1995; 22(2): 344-6.
[PMID: 7738962]
[11]
Kinonen C, Gattuso P, Reddy VB. Lupus mastitis. Am J Surg Pathol 2010; 34(6): 901-6.
[http://dx.doi.org/10.1097/PAS.0b013e3181da00fb] [PMID: 20410809]
[12]
Wang YC, Chou CP, Levenson RB, Hsieh PP, Huang JS, Pan HB. Imaging features of bilateral lupus mastitis. Breast J 2010; 16(2): 203-4.
[http://dx.doi.org/10.1111/j.1524-4741.2009.00869.x] [PMID: 20030651]
[13]
Sabaté JM, Gómez A, Torrubia S, Salinas T, Clotet M, Lerma E. Lupus panniculitis involving the breast. Eur Radiol 2006; 16(1): 53-6.
[http://dx.doi.org/10.1007/s00330-005-2810-1] [PMID: 15937681]
[14]
Sharma A, Blank A, Komforti MK. Rare initial manifestation of lupus as lobular panniculitis of the breast-A case report and review of the literature. Am J Dermatopathol 2021; 43(5): 381-5.
[http://dx.doi.org/10.1097/DAD.0000000000001846] [PMID: 33201011]
[15]
Crevits J, Van Steen A, Van Ongeval C, Marchal G. Unilateral calcifying lupus mastitis in a male breast. Breast J 2009; 15(3): 307-8.
[http://dx.doi.org/10.1111/j.1524-4741.2009.00725.x] [PMID: 19645791]
[16]
Fernandez-Flores A, Crespo LG, Alonso S, Montero MG. Lupus mastitis in the male breast mimicking inflammatory carcinoma. Breast J 2006; 12(3): 272-3.
[http://dx.doi.org/10.1111/j.1075-122X.2006.00256.x] [PMID: 16684330]
[17]
Arsenovic N, Terzic M. Lupus mastitis mimicking a breast tumor. J Obstet Gynaecol Res 2008; 34(5): 919-21.
[http://dx.doi.org/10.1111/j.1447-0756.2008.00858.x] [PMID: 18834351]
[18]
Carducci M, Mussi A, Lisi S, Muscardin L, Solivetti FM. Lupus mastitis: A 2-year history of a single localization of lupus erythematosus mimicking breast carcinoma. J Eur Acad Dermatol Venereol 2005; 19(2): 260-2.
[http://dx.doi.org/10.1111/j.1468-3083.2005.01030.x] [PMID: 15752311]
[19]
Cerveira I, Costa Matos L, Garrido A, et al. Lupus mastitis. Breast 2006; 15(5): 670-2.
[http://dx.doi.org/10.1016/j.breast.2006.03.011] [PMID: 16737816]
[20]
Bayar S, Dusunceli E, Ceyhan K, Ünal E, Turgay M. Lupus mastitis is not a surgical disease. Breast J 2007; 13(2): 187-8.
[http://dx.doi.org/10.1111/j.1524-4741.2007.00402.x] [PMID: 17319861]
[21]
Georgian-Smith D, Lawton TJ, Moe RE, Couser WG. Lupu masstitis. AJR Am J Roentgenol 2002; 178(5): 1233-5.
[http://dx.doi.org/10.2214/ajr.178.5.1781233] [PMID: 11959738]
[22]
Lee SJ, Saidian L, Wahab RA, Khan S, Mahoney MC. The evolving imaging features of lupus mastitis. Breast J 2019; 25(4): 753-4.
[http://dx.doi.org/10.1111/tbj.13314] [PMID: 31074031]
[23]
Whitaker-Worth DL, Carlone V, Susser WS, Phelan N, Grant-Kels JM. Dermatologic diseases of the breast and nipple. J Am Acad Dermatol 2000; 43(5): 733-54.
[http://dx.doi.org/10.1067/mjd.2000.109303] [PMID: 11050577]
[24]
Rosa M. “Inflammatory” changes in breast: How to provide a better care to our patients. Arch Gynecol Obstet 2010; 281(5): 901-5.
[http://dx.doi.org/10.1007/s00404-009-1236-4] [PMID: 19789887]
[25]
Oktay A, Esmat HA, Aslan Ö, Mirzafarli I. Lupus mastitis in a young female mimicking a breast carcinoma; a rare entity through a case report and review of the literature. Eur J Breast Health 2022; 18(1): 13-5.
[http://dx.doi.org/10.4274/ejbh.galenos.2021.6361] [PMID: 35059586]

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