Generic placeholder image

Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Review Article

1,3,4-Oxadiazole and Its Analogs: Recently Adopted Synthetic Approaches and Interaction with Targets

Author(s): Greesh Kumar, Rajnish Kumar*, Avijit Mazumder, Salahuddin and Upendra Kumar

Volume 21, Issue 12, 2024

Published on: 24 August, 2023

Page: [2335 - 2351] Pages: 17

DOI: 10.2174/1570180820666230701000317

Price: $65

Abstract

1,3,4-Oxadiazole is a five-membered heterocyclic compound with one oxygen, two nitrogen, and two carbon atoms arranged in a ring. Several research reports, patents, and marketed drugs have already established 1,3,4-oxadiazole and its analog as potential molecules having a diverse range of pharmacological activities. In this review, we focused on recently acknowledged straightforward synthesis approaches for 1,3,4-oxadiazole and its analogs. Additionally, interactions of the 1,3,4-oxadiazole derivative with different biological targets (enzymes and receptors) have been described. The present findings discussed in this review analysis will aid researchers in conducting future research on 1,3,4-oxadiazole.


© 2024 Bentham Science Publishers | Privacy Policy