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Current Protein & Peptide Science

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ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

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Editorial

Vitamin D: A Repurposed Anti-inflammatory Drug at the Cardiovascular Level

Author(s): Virna Margarita Martín Giménez, Sebastián García Menéndez, Michael F. Holick and Walter Manucha*

Volume 24, Issue 7, 2023

Published on: 17 July, 2023

Page: [533 - 535] Pages: 3

DOI: 10.2174/1389203724666230622162539

Price: $65

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[1]
Pushpakom, S.; Iorio, F.; Eyers, P.A.; Escott, K.J.; Hopper, S.; Wells, A.; Doig, A.; Guilliams, T.; Latimer, J.; McNamee, C.; Norris, A.; Sanseau, P.; Cavalla, D.; Pirmohamed, M. Drug repurposing: Progress, challenges and recommendations. Nat. Rev. Drug Discov., 2019, 18(1), 41-58.
[http://dx.doi.org/10.1038/nrd.2018.168] [PMID: 30310233]
[2]
Holick, M.F.; Mazzei, L.; García Menéndez, S.; Martín Giménez, V.M.; Al Anouti, F.; Manucha, W. Genomic or non-genomic? A question about the pleiotropic roles of Vitamin D in Inflammatorybased diseases. Nutrients, 2023, 15(3), 767.
[http://dx.doi.org/10.3390/nu15030767] [PMID: 36771473]
[3]
Martín Giménez, V.M.; Chuffa, L.G.A.; Simão, V.A.; Reiter, R.J.; Manucha, W. Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved. Life Sci., 2022, 288, 120191.
[http://dx.doi.org/10.1016/j.lfs.2021.120191] [PMID: 34856208]
[4]
Sorokin, V.; Vickneson, K.; Kofidis, T.; Woo, C.C.; Lin, X.Y.; Foo, R.; Shanahan, C.M. Role of vascular smooth muscle cell plasticity and interactions in vessel wall inflammation. Front. Immunol., 2020, 11, 599415.
[http://dx.doi.org/10.3389/fimmu.2020.599415] [PMID: 33324416]
[5]
Sanz, R.; Mazzei, L.; Santino, N.; Ingrasia, M.; Manucha, W. Vitamin D-mitochondria cross-talk could modulate the signaling pathway involved in hypertension development: A translational integrative overview. Clin. Investig. Arterioscler., 2020, 32(4), 144-155.
[PMID: 32456803]
[6]
Pál, É.; Ungvári, Z.; Benyó, Z.; Várbíró, S. Role of Vitamin D deficiency in the pathogenesis of cardiovascular and cerebrovascular diseases. Nutrients, 2023, 15(2), 334.
[http://dx.doi.org/10.3390/nu15020334] [PMID: 36678205]

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