Generic placeholder image

Current Drug Discovery Technologies

Editor-in-Chief

ISSN (Print): 1570-1638
ISSN (Online): 1875-6220

Research Article

Investigating the Effects and Side Effects of Two Antipsychotic Drugs in the Treatment of Children and Adolescents with Tourette Syndrome: A Semi-experimental Research

Author(s): Atefeh Soltanifar, Raheleh Lashkarnevis, Maliheh Ziaee, Fatemeh Moharari, Roya Samadi, Azadeh Soltanifar and Maedeh Kamrani*

Volume 20, Issue 6, 2023

Published on: 26 June, 2023

Article ID: e090623217825 Pages: 8

DOI: 10.2174/1570163820666230609095720

Price: $65

Abstract

Introduction: Due to the high prevalence of Tourette's disorder among children and adolescents and its negative consequences, an appropriate and effective medical treatment with minimal complications is necessary. Therefore, this study was conducted to compare the effects of Aripiprazole and Risperidone on Tourette's disorders in children and adolescents.

Methods: The statistical population of this semi-experimental study was children and adolescents aged seven to eighteen years old. They were diagnosed with Tourette's disorder based on the DSM-V criteria by the clinical interview of a child and adolescent psychiatrist in the child Psychiatry clinic of Ibne- Sina's Psychiatric Hospital (Mashhad-Iran) in 2018. A total of forty participants were selected by the convenience sampling method, and they were randomly divided into two groups treated with medicines, Risperidone or Aripiprazole, for two months. Then, the demographic information questionnaire was completed. The Y-GTSS Scale was completed. The clinical Effect Rating Scale (CGI-Tics Scale) was completed. Calculation of body mass index and medical side effects complications were completed. The evaluation was carried out at the beginning and on the second, fourth, and eighth weeks, and the results were compared. The data were analyzed using SPSS software. 14, descriptive statistics, Chi-square, and variance analysis.

Results: The two groups were homogeneous in terms of demographic variables and body mass index. Despite the positive effect of both medicines, no significant difference was observed among the general scores of such disorders, the overall score of severity, Tourette's recovery, and BMI of these two groups at the intervals and the end of treatments. (p <0.05). Due to the low number of complications reported, statistical comparisons of the medical side effects were not made.

Conclusion: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.

Graphical Abstract

[1]
Sadock BJ, Sadock VA, Ruiz P. Comprehensive textbook of psychiatry. (10th ed.), 2017.
[2]
Robertson MM, Eapen V, Cavanna AE. The international prevalence, epidemiology, and clinical phenomenology of Tourette syndrome: A cross-cultural perspective. J Psychosom Res 2009; 67(6): 475-83.
[http://dx.doi.org/10.1016/j.jpsychores.2009.07.010] [PMID: 19913651]
[3]
Sun N, Tischfield JA, King RA, Heiman GA. Functional evaluations of genes disrupted in patients with Tourette’s disorder. Front Psychiatry 2016; 7: 11.
[http://dx.doi.org/10.3389/fpsyt.2016.00011] [PMID: 26903887]
[4]
Ünal D, Akdemir D. Neurobiology of tourette syndrome. Turk Psikiyatr Derg 2016; 27(4): 275-85.
[PMID: 28046197]
[5]
Kurlan R. Tourette’s syndrome. N Engl J Med 2010; 363(24): 2332-8.
[http://dx.doi.org/10.1056/NEJMcp1007805] [PMID: 21142535]
[6]
Ganos C. Tics and Tourette’s: update on pathophysiology and Tic control. Curr Opin Neurol 2016; 29(4): 513-8.
[http://dx.doi.org/10.1097/WCO.0000000000000356] [PMID: 27310537]
[7]
Nagy P, Bognár E, Farkas L, et al. Clinical characteristics of children with tourette’s syndrome. Psychiatr Hung 2020; 35(1): 37-45.
[PMID: 31854321]
[8]
Rose O, Hartmann A, Worbe Y, Scharf JM, Black KJ. Tourette syndrome research highlights from 2018. F1000 Res 2019; 8: 988.
[http://dx.doi.org/10.12688/f1000research.19542.1]
[9]
Surén P, Bakken IJ, Skurtveit S, et al. Tourette syndrome in children in Norway. Tidsskr Nor Laegeforen 2019; 139(17)
[http://dx.doi.org/10.4045/tidsskr.19.0411]
[10]
Szejko N, Jakubczyk A, Janik P. Prevalence and clinical correlates of self-harm behaviors in Gilles de la Tourette syndrome. Front Psychiatry 2019; 10: 638.
[http://dx.doi.org/10.3389/fpsyt.2019.00638] [PMID: 31543843]
[11]
Rizzo R, Gulisano M. Treatment options for Tic disorders. Expert Rev Neurother 2020; 20(1): 55-63.
[http://dx.doi.org/10.1080/14737175.2020.1698950] [PMID: 31795779]
[12]
Chen CW, Wang HS, Chang HJ, Hsueh CW. Effectiveness of a modified comprehensive behavioral intervention for Tics for children and adolescents with tourette’s syndrome: A randomized controlled trial. J Adv Nurs 2020; 76(3): 903-15.
[http://dx.doi.org/10.1111/jan.14279] [PMID: 31782167]
[13]
Deeb W, Malaty IA, Mathews CA. Tourette disorder and other Tic disorders. Handb Clin Neurol 2019; 165: 123-53.
[http://dx.doi.org/10.1016/B978-0-444-64012-3.00008-3] [PMID: 31727209]
[14]
Gill CE, Kompoliti K. Clinical features of tourette syndrome. J Child Neurol 2020; 35(2): 166-74.
[http://dx.doi.org/10.1177/0883073819877335] [PMID: 31608744]
[15]
Benaroya-Milshtein N, Shmuel-Baruch S, Apter A, Valevski A, Fenig S, Steinberg T. Aggressive symptoms in children with Tic disor-ders. Eur Child Adolesc Psychiatry 2020; 29: 617-24.
[http://dx.doi.org/10.1007/s00787-019-01386-6] [PMID: 31396706]
[16]
Openneer TJC, Tárnok Z, Bognar E, et al. The Premonitory Urge for Tics Scale in a large sample of children and adolescents: Psychometric properties in a developmental context. An EMTICS study. Eur Child Adolesc Psychiatry 2020; 29: 1411-24.
[http://dx.doi.org/10.1007/s00787-019-01450-1] [PMID: 31802271]
[17]
Mustafa S, Joober R, Iyer S, Shah J, Lepage M, Malla A. Early stabilization of weight changes following treatment with olanzapine, risperidone, and aripiprazole: A 12-month naturalistic study of first episode psychosis. J Clin Psychiatry 2019; 80(5): 1087.
[http://dx.doi.org/10.4088/JCP.18m12717]
[18]
Padala PR, Qadri SF, Madaan V. Aripiprazole for the treatment of Tourette’s disorder. Prim Care Companion J Clin Psychiatry 2005; 7(6): 296-9.
[PMID: 16498492]
[19]
Budman C, Coffey BJ, Shechter R, et al. Aripiprazole in children and adolescents with Tourette disorder with and without explosive outbursts. J Child Adolesc Psychopharmacol 2008; 18(5): 509-15.
[http://dx.doi.org/10.1089/cap.2007.061] [PMID: 18928415]
[20]
Liu Y, Chen Y, Chen H, Liu Z. A control study of aripiprazole and tiapride treatment for Tic disorders in children. Chin J. Contemp Pediatr 2010; 12(6): 421-4.
[21]
Davies L, Stern JS, Agrawal N, Robertson MM. A case series of patients with Tourette’s syndrome in the United Kingdom treated with aripiprazole. Hum Psychopharmacol 2006; 21(7): 447-53.
[http://dx.doi.org/10.1002/hup.798] [PMID: 17029306]
[22]
Murphy TK, Mutch PJ, Reid JM, et al. Open label aripiprazole in the treatment of youth with Tic disorders. J Child Adolesc Psychopharmacol 2009; 19(4): 441-7.
[http://dx.doi.org/10.1089/cap.2008.0149] [PMID: 19702496]
[23]
Yoo HK, Choi SH, Park S, Wang HR, Jin-Pyo J-P, Kim CY. An open-label study of the efficacy and tolerability of aripiprazole for children and adolescents with Tic disorders. J Clin Psychiatry 2007; 68(7): 1089-94.
[http://dx.doi.org/10.4088/JCP.v68n0717] [PMID: 17685747]
[24]
Lyon GJ, Samar S, Jummani R, et al. Aripiprazole in children and adolescents with Tourette’s disorder: An open-label safety and tolerability study. J Child Adolesc Psychopharmacol 2009; 19(6): 623-33.
[http://dx.doi.org/10.1089/cap.2009.0035] [PMID: 20035580]
[25]
Ghanizadeh A, Haghighi A. Aripiprazole versus risperidone for treating children and adolescents with Tic disorder: A randomized double blind clinical trial. Child Psychiatry Hum Dev 2014; 45(5): 596-603.
[http://dx.doi.org/10.1007/s10578-013-0427-1] [PMID: 24343476]
[26]
Yoo HK, Lee JS, Paik KW, et al. Open-label study comparing the efficacy and tolerability of aripiprazole and haloperidol in the treatment of pediatric Tic disorders. Eur Child Adolesc Psychiatry 2011; 20(3): 127-35.
[http://dx.doi.org/10.1007/s00787-010-0154-0] [PMID: 21188439]
[27]
Cox J, Seri S, Cavanna A. Safety and efficacy of aripiprazole for the treatment of pediatric Tourette syndrome and other chronic Tic disorders. Pediatric Health Med Ther 2016; 7: 57-64.
[http://dx.doi.org/10.2147/PHMT.S87121]
[28]
Jeon S, Walkup JT, Woods DW, et al. Detecting a clinically meaningful change in Tic severity in Tourette syndrome: A comparison of three methods. Contemp Clin Trials 2013; 36(2): 414-20.
[http://dx.doi.org/10.1016/j.cct.2013.08.012] [PMID: 24001701]
[29]
Hasanpour-Dehkordi A, Safavi P. AmirAhmadi M. Comparison of risperidone and aripiprazole in the treatment of preschool children with disruptive behavior disorder and attention deficit-hyperactivity disorder: A randomized clinical trial. J Adv Pharm Technol Res 2016; 7(2): 43-7.
[http://dx.doi.org/10.4103/2231-4040.177203] [PMID: 27144151]
[30]
Yang C, Yi Q, Zhang L, Cui H, Mao J. Safety of aripiprazole for Tics in children and adolescents. Medicine 2019; 98(22): e15816.
[http://dx.doi.org/10.1097/MD.0000000000015816] [PMID: 31145316]
[31]
Frölich J, Starck M, Banaschewski T, Lehmkuhl G. A drug treatment alternative for Tourette’s syndrome in children and adolescents. Z Kinder Jugendpsychiatr Psychother 2010; 38: 291-8.
[http://dx.doi.org/10.1024/1422-4917/a000049] [PMID: 20617499]
[32]
Cui Y, Zheng Y, Yang Y, Liu J, Li J. Effectiveness and tolerability of aripiprazole in children and adolescents with Tourette’s disorder: A pilot study in China. J Child Adolesc Psychopharmacol 2010; 20(4): 291-8.
[http://dx.doi.org/10.1089/cap.2009.0125] [PMID: 20807067]
[33]
Murphy TK, Bengtson MA, Soto O, et al. Case series on the use of aripiprazole for Tourette syndrome. Int J Neuropsychopharmacol 2005; 8(3): 489-90.
[http://dx.doi.org/10.1017/S1461145705005365] [PMID: 15857570]

Rights & Permissions Print Cite
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version809msRequest Duration28MBMemory UsageGET article/{article_id}/{param?}Route
  • warninglog[20:26:28] LOG.warning: Optional parameter $article_id declared before required parameter $request i...
  • warninglog[20:26:29] LOG.warning: Function strftime() is deprecated in /home/alphaeurekaselec/public_html/stor...
  • warninglog[20:26:29] LOG.warning: trim(): Passing null to parameter #1 ($string) of type string is deprecated ...
  • warninglog[20:26:29] LOG.warning: Function strftime() is deprecated in /home/alphaeurekaselec/public_html/stor...
  • Booting (284ms)time
  • Application (525ms)time
  • 1 x Application (64.86%)
    525ms
    1 x Booting (35.13%)
    284ms
    14 templates were rendered
    • articlearticle.blade.php#?blade
    • includes.article_top_bannerarticle_top_banner.blade.php#?blade
    • includes.article_referencearticle_reference.blade.php#?blade
    • export_citation_formexport_citation_form.blade.php#?blade
    • includes.article_bottom_bannerarticle_bottom_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • includes.journal_rightmenujournal_rightmenu.blade.php#?blade
    • includes.journal_right_bannerjournal_right_banner.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET article/{article_id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ArticleController@GetArticleDetails
    namespace
    App\Http\Controllers
    where
    as
    article
    file
    app/Http/Controllers/ArticleController.php:1974-2510
    36 statements were executed, 4 of which were duplicates, 32 unique. Show only duplicated360ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('314383442','',1,1740774388,1740774388) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1740774388
      1.26msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('314383442','/article/132427',1,1740774388,1740774388)
      220μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 314383442 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 314383442) limit 1
      19.01msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 314383442
      • 1: 314383442
      • 2: 314383442
      • 3: 314383442
      • 4: 314383442
      • 5: 314383442
      • 6: 314383442
      • 7: 314383442
      • 8: 314383442
      • 9: 314383442
      • 10: 314383442
      • 11: 314383442
      • 12: 314383442
      • 13: 314383442
      • 14: 314383442
      • 15: 314383442
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • SELECT at.type_name, p.copyright, p.publisher_location,m.month,y.year, a.publish_on, a.nid article_nid,a.article_id, a.pmid, a.issue_id, a.title, a.abstract,a.podcast,a.altmetric_score,a.altmetric_url,a.kudos_url, a.page_count, a.first_page, a.elocator, a.last_page, i.publication_date, a.file_name, a.file_path, a.doi, a.is_epub,a.epub_type, a.volume_id, a.is_uploaded, a.editor_choice, a.is_epub, j.image_file_name, a.article_no, a.art_type AS article_type, a.supplementary_filename,a.html_filename,a.prc_filename,a.epub_filename, a.graph_abs_lg_filename, a.graph_abs_sm_filename, a.oa_image_lg_filename, a.oa_image_sm_filename, j.journal_banner,a.animated_abstract,a.erratum_in,a.erratum_for, (CASE WHEN a.issue_id =0 THEN j.epub_price ELSE j.price END) AS sell_price, j.epub_price, j.nid AS jour_nid, j.title AS journal_title, j.issn, j.eissn,j.journal_id, j.subtitle AS jour_subtitle, v.volume_id,v.volume_name AS volume, v.year_id, i.title AS issue, i.month_id ,i.type issue_type, j.subtitle,j.formerly_title, ac.subtitle AS epub_title,a.crossmark_enabled,a.text_mining_urls,a.license_urls,a.created, a.receivedate, a.revisedate, a.acceptdate,js.js_title FROM article a LEFT JOIN article_section ac ON a.is_epub = ac.art_sec_id LEFT JOIN journal_section js ON a.js_id = js.js_id LEFT JOIN article_type at ON a.art_type = at.art_type_id LEFT JOIN issue i ON a.issue_id = i.issue_id LEFT JOIN month m ON m.id = i.month_id LEFT JOIN volume v ON v.volume_id = a.volume_id INNER JOIN year y ON y.id = v.year_id INNER JOIN journal j ON j.journal_id = a.journal_id INNER JOIN publisher p ON p.publisher_id = j.publisher_id WHERE a.article_id=132427
      1.03msalphaeurekaselec_live_10_06_2022Article.php#408
      Backtrace
      • 11. app/Models/Article.php:408
      • 12. app/Http/Controllers/ArticleController.php:2515
      • 13. app/Http/Controllers/ArticleController.php:2035
      • 14. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 15. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `journal` where `journal_id` = 68 limit 1
      1.12msalphaeurekaselec_live_10_06_2022Journal.php#64
      Bindings
      • 0: 68
      Backtrace
      • 14. app/Models/Journal.php:64
      • 15. app/Http/Controllers/ArticleController.php:2516
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=68) and sj.journal_id!=68 group by `j`.`nid`) as `aggregate_table`
      1.57msalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 16. app/Models/Subject.php:200
      • 17. app/Http/Controllers/ArticleController.php:2517
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select j.nid as journal_nid,j.flyer_link,j.title ,j.issn,j.eissn,j.keyword, j.journal_id as journal_id, j.subtitle, j.image_file_name,j.description,j.journal_insight_url,j.doi from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where j.journal_status=1 and subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=68) and sj.journal_id!=68 group by `j`.`nid` order by `j`.`journal_id` asc limit 10 offset 0
      1.35msalphaeurekaselec_live_10_06_2022Subject.php#200
      Backtrace
      • 14. app/Models/Subject.php:200
      • 15. app/Http/Controllers/ArticleController.php:2517
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select count(*) as aggregate from (select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=68) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid`) as `aggregate_table`
      3.81msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 16. app/Models/Subject.php:220
      • 17. app/Http/Controllers/ArticleController.php:2518
      • 18. app/Http/Controllers/ArticleController.php:2035
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 20. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `se`.`ebook_id` inner join `year` as `y` on `y`.`id` = `v`.`year_id` where subject_id IN (SELECT subject_id FROM subject_journal WHERE journal_id=68) and v.ebook_status='1' and y.year > 2020 group by `v`.`nid` order by `v`.`ebook_volume_id` desc limit 10 offset 0
      11.23msalphaeurekaselec_live_10_06_2022Subject.php#220
      Backtrace
      • 14. app/Models/Subject.php:220
      • 15. app/Http/Controllers/ArticleController.php:2518
      • 16. app/Http/Controllers/ArticleController.php:2035
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `keywords` where `article_id` = '132427'
      450μsalphaeurekaselec_live_10_06_2022Keywords.php#43
      Bindings
      • 0: 132427
      Backtrace
      • 13. app/Models/Keywords.php:43
      • 14. app/Http/Controllers/ArticleController.php:2519
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select * from `article_citation` where `article_id` = '132427'
      28.51msalphaeurekaselec_live_10_06_2022Article.php#1570
      Bindings
      • 0: 132427
      Backtrace
      • 13. app/Models/Article.php:1570
      • 14. app/Http/Controllers/ArticleController.php:2520
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`article_id` = '132427' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      15.7msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 132427
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ArticleController.php:2533
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      590μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2535
      • 15. app/Http/Controllers/ArticleController.php:2035
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • select `subtitle` from `journal` where `continues_publication_journal` = 1
      1.58msalphaeurekaselec_live_10_06_2022Article.php#1960
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/Article.php:1960
      • 14. app/Http/Controllers/ArticleController.php:2062
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 68 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
      57.74msalphaeurekaselec_live_10_06_2022Issue.php#298
      Backtrace
      • 11. app/Models/Issue.php:298
      • 12. app/Http/Controllers/ArticleController.php:2068
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 68 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      30.35msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2070
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 68 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`publish_on` desc
      5.82msalphaeurekaselec_live_10_06_2022Article.php#528
      Backtrace
      • 13. app/Models/Article.php:528
      • 14. app/Http/Controllers/ArticleController.php:2071
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select pdf, html, epub, prc from `article_metrics` where `article_id` = 132427 limit 1
      480μsalphaeurekaselec_live_10_06_2022Article.php#744
      Bindings
      • 0: 132427
      Backtrace
      • 14. app/Models/Article.php:744
      • 15. app/Http/Controllers/ArticleController.php:2091
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from content_by_diseases where content_id = 132427 and content_type = 'article' order by status desc limit 1
      370μsalphaeurekaselec_live_10_06_2022Article.php#751
      Backtrace
      • 11. app/Models/Article.php:751
      • 12. app/Http/Controllers/ArticleController.php:2094
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `node_meta` where `nid` = 217825 limit 1
      270μsalphaeurekaselec_live_10_06_2022Meta.php#30
      Bindings
      • 0: 217825
      Backtrace
      • 14. app/Models/Meta.php:30
      • 15. app/Http/Controllers/ArticleController.php:2101
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `bo`.* from `bundle_offer` as `bo` where `bo`.`bundle_status` = 'A' order by `bo`.`bundle_id` desc
      310μsalphaeurekaselec_live_10_06_2022BundleOffer.php#57
      Bindings
      • 0: A
      Backtrace
      • 13. app/Models/BundleOffer.php:57
      • 14. app/Http/Controllers/ArticleController.php:2108
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `tbl_ht_submission` as `h` where `h`.`subtitle` = 'CDDT' and (h.proposal_closing_date = 0 OR TO_DAYS(FROM_UNIXTIME(h.proposal_closing_date)) >= TO_DAYS(NOW())) order by `h`.`manuscript` asc
      370μsalphaeurekaselec_live_10_06_2022Article.php#2025
      Bindings
      • 0: CDDT
      Backtrace
      • 13. app/Models/Article.php:2025
      • 14. app/Http/Controllers/ArticleController.php:2112
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '132427' and content_type = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      520μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2186
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '12821' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      460μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2207
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '3347' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      420μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ArticleController.php:2231
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3347) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3347) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3347)
      163msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2272
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 12821) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 12821) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 12821)
      1.04msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2297
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 132427) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 132427) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314383442 and j.to_ip >=314383442 )) and ((j.from_date <= 1740774389 and j.to_date >= 1740774389 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.article_id = 132427)
      920μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ArticleController.php:2329
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `first_page` < '1' and is_uploaded = 1 and issue_id = 12821 order by cast(first_page as SIGNED) desc limit 1
      820μsalphaeurekaselec_live_10_06_2022Article.php#1819
      Bindings
      • 0: 1
      Backtrace
      • 14. app/Models/Article.php:1819
      • 15. app/Http/Controllers/ArticleController.php:2470
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `article` where `last_page` > '8' and is_uploaded = 1 and issue_id = 12821 order by cast(first_page as SIGNED) asc limit 1
      640μsalphaeurekaselec_live_10_06_2022Article.php#1831
      Bindings
      • 0: 8
      Backtrace
      • 14. app/Models/Article.php:1831
      • 15. app/Http/Controllers/ArticleController.php:2472
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `language_id` from `multilanguage` where `short_code` = 'en'
      270μsalphaeurekaselec_live_10_06_2022ArticleController.php#2497
      Bindings
      • 0: en
      Backtrace
      • 14. app/Http/Controllers/ArticleController.php:2497
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select `source_lang_label`, `target_lang_label` from `multilanguage_labels` where `target_lang_id` = 1
      320μsalphaeurekaselec_live_10_06_2022MultiLanguage.php#23
      Bindings
      • 0: 1
      Backtrace
      • 13. app/Models/MultiLanguage.php:23
      • 14. app/Http/Controllers/ArticleController.php:2498
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `id` from `multilanguage_article` where `article_id` = 132427 limit 1
      4msalphaeurekaselec_live_10_06_2022ArticleController.php#2506
      Bindings
      • 0: 132427
      Backtrace
      • 16. app/Http/Controllers/ArticleController.php:2506
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 68 and `b`.`banner_from_date` <= 1740774389 and `b`.`banner_to_date` >= 1740774389 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.74msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 68
      • 3: 1740774389
      • 4: 1740774389
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 68 and `b`.`banner_from_date` <= 1740774389 and `b`.`banner_to_date` >= 1740774389 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.64msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: J
      • 2: 68
      • 3: 1740774389
      • 4: 1740774389
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='a79830b99fa730dd7781c6a04ecdf436'
      1.51msalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:291
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\MultiLanguage
    1MultiLanguage.php#?
        _token
        D8ee3FGTtIWkszJVaIVgOdTyIhAicbdMbhcaTJWp
        uc_cart_id
        a79830b99fa730dd7781c6a04ecdf436
        _previous
        array:1 [ "url" => "http://alpha.eurekaselect.com/article/132427" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /article/132427
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:8 [ "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "keep-alive" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] ]
        request_cookies
        []
        
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Fri, 28 Feb 2025 20:26:29 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6ImwyRTFwbEQ0TlVEKzdKVXFjM1RsWWc9PSIsInZhbHVlIjoia0JOamtLUmptdlFyUVZsQ292S2JWa0lVcE91Mm5FVVdma1c3bUhSejNFUjgxVlNNZzduUFJ4M2pnbU0rMTAvZXVKdmVjYlR0WHpxWXovL2FuWk44RU11eU02UlU5djljcWlaV0Q5M3B6eUxUZVpQeExaZ3JkYjBIMmZaUzhZWXgiLCJtYWMiOiIwOTZhMjVkMmY1ZDdiYzU3MWFlNTYwOWY5N2MxZDJiZThlNjI3MmFiOTdmNDhkZTI2ZGJlYTUyODYzODUxZDc4IiwidGFnIjoiIn0%3D; expires=Mon, 03 Mar 2025 08:26:29 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6ImwyRTFwbEQ0TlVEKzdKVXFjM1RsWWc9PSIsInZhbHVlIjoia0JOamtLUmptdlFyUVZsQ292S2JWa0lVcE91Mm5FVVdma1c3bUhSejNFUjgxVlNNZzduUFJ4M2pnbU0rMTAvZXVKdmVjY" 1 => "alphaeurekaselectnet_session=eyJpdiI6InVzK3lNbHk2UVEzYTQrOCtyeFdLL2c9PSIsInZhbHVlIjoiMkJKUEtlczVJVFVxRTFmRXF0VjRYNUlrdzJrUVlUdnlOclBCOXp0aE9KUXk3UDl5SDRMbHhKeHBwNDNBSUhLWkdoZ2FlZE5XdDAyZkdYczZFaW5vL3poV3dvdFpUaExMVjJoMmRyd2JYQjhrQzJVUGRPTlloUzVYOEkwUXIyVUMiLCJtYWMiOiJkNDc5MzZlMzAxN2Y2NmMwZmIxYzZlYzFlOGM3NmUzOTExOTUyNzkwNTI1YTExYzNmMTNjZjNjN2RmOGYxZGYzIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6InVzK3lNbHk2UVEzYTQrOCtyeFdLL2c9PSIsInZhbHVlIjoiMkJKUEtlczVJVFVxRTFmRXF0VjRYNUlrdzJrUVlUdnlOclBCOXp0aE9KUXk3UDl5SDRMbHhKeHB" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6ImwyRTFwbEQ0TlVEKzdKVXFjM1RsWWc9PSIsInZhbHVlIjoia0JOamtLUmptdlFyUVZsQ292S2JWa0lVcE91Mm5FVVdma1c3bUhSejNFUjgxVlNNZzduUFJ4M2pnbU0rMTAvZXVKdmVjYlR0WHpxWXovL2FuWk44RU11eU02UlU5djljcWlaV0Q5M3B6eUxUZVpQeExaZ3JkYjBIMmZaUzhZWXgiLCJtYWMiOiIwOTZhMjVkMmY1ZDdiYzU3MWFlNTYwOWY5N2MxZDJiZThlNjI3MmFiOTdmNDhkZTI2ZGJlYTUyODYzODUxZDc4IiwidGFnIjoiIn0%3D; expires=Mon, 03-Mar-2025 08:26:29 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6ImwyRTFwbEQ0TlVEKzdKVXFjM1RsWWc9PSIsInZhbHVlIjoia0JOamtLUmptdlFyUVZsQ292S2JWa0lVcE91Mm5FVVdma1c3bUhSejNFUjgxVlNNZzduUFJ4M2pnbU0rMTAvZXVKdmVjY" 1 => "alphaeurekaselectnet_session=eyJpdiI6InVzK3lNbHk2UVEzYTQrOCtyeFdLL2c9PSIsInZhbHVlIjoiMkJKUEtlczVJVFVxRTFmRXF0VjRYNUlrdzJrUVlUdnlOclBCOXp0aE9KUXk3UDl5SDRMbHhKeHBwNDNBSUhLWkdoZ2FlZE5XdDAyZkdYczZFaW5vL3poV3dvdFpUaExMVjJoMmRyd2JYQjhrQzJVUGRPTlloUzVYOEkwUXIyVUMiLCJtYWMiOiJkNDc5MzZlMzAxN2Y2NmMwZmIxYzZlYzFlOGM3NmUzOTExOTUyNzkwNTI1YTExYzNmMTNjZjNjN2RmOGYxZGYzIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6InVzK3lNbHk2UVEzYTQrOCtyeFdLL2c9PSIsInZhbHVlIjoiMkJKUEtlczVJVFVxRTFmRXF0VjRYNUlrdzJrUVlUdnlOclBCOXp0aE9KUXk3UDl5SDRMbHhKeHB" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "D8ee3FGTtIWkszJVaIVgOdTyIhAicbdMbhcaTJWp" "uc_cart_id" => "a79830b99fa730dd7781c6a04ecdf436" "_previous" => array:1 [ "url" => "http://alpha.eurekaselect.com/article/132427" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-28 20:26:29GET/article/132427414361