Administration of Inhibitory Molecules through Nanoparticles in
Breast Cancer Therapy

Christian   Rafael   Quijia; Andreina   Quevedo   Enríquez; Carlos Daniel      Zappia; Roxana   Noemí   Peroni; Marlus      Chorilli
doi:10.2174/0929867330666230608145125
Abstract

According to Global Cancer Statistics, breast cancer is the second leading cause of mortality in women. While there are several treatments for breast cancer, they are not always effective. In most cases, after initial treatment, patients may present a low response to therapy, more severe relapses, and even drug resistance. Hence, more effective and targeted therapies are needed. Recently, the use of nanoparticles has emerged as a promising alternative that will allow the controlled release of drugs in response to stimuli, precise delivery to the site of action, lower levels of toxicity, and fewer side effects. In this review, we provide an overview of the recent evidence proposing the delivery of inhibitory molecules encapsulated in nanoparticles as a new therapy for breast cancer that targets the signaling pathways governing the processes of tumor formation, maintenance, and expansion.
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DOI https://dx.doi.org/10.2174/0929867330666230608145125	Print ISSN 0929-8673
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Current Medicinal Chemistry

Administration of Inhibitory Molecules through Nanoparticles in Breast Cancer Therapy

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