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Mini-Reviews in Organic Chemistry

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ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

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Review Article

Chemistry of Thieno [2,3-h]-/[3,2-h] Quinoline and Thieno [2,3-f]-/[3,2-f] Quinoline Derivatives Part (x), Reactivities, and Biological Activities

Author(s): Moustafa A. Gouda*, Nahlah A. Al-Hadhrami, Amin A. Abu-Hashem, Ahmed A.M. Abdelgawad and Mohamed A. Salem

Volume 21, Issue 6, 2024

Published on: 23 June, 2023

Page: [671 - 683] Pages: 13

DOI: 10.2174/1570193X20666230525120540

Price: $65

Abstract

Several thieno [2,3-h] /[3,2-h] quinolines and thieno [2,3-f] /[3,2-f] quinolines (TQs) are discussed in this review from a few perspectives, including various preparation and processing methods employing cutting-edge machinery. The preparation of (TQs), from 4-(5)aminobenzothiophene, 2(3)chloromethylthiophene, 2(3)thienylboric acid, and other chemical reagents is illustrated via a number of chemical procedures in this review. The formation of (TQs) was clarified using the Michael addition, Photocyclization, Skraup reaction, Ullmann-Fetvadjian process, Suzuki-Miyaura and Sonogashira reaction, aza-Diels-Alder reaction, and Friedel-Crafts reaction.

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Graphical Abstract

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