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Pharmaceutical Nanotechnology

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ISSN (Print): 2211-7385
ISSN (Online): 2211-7393

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Review Article

Niosomes: A Smart Drug Delivery System for Brain Targeting

Author(s): Sandesh Varshney, Md. Aftab Alam*, Awaneet Kaur and Shivang Dhoundiyal

Volume 12, Issue 2, 2024

Published on: 07 July, 2023

Page: [108 - 125] Pages: 18

DOI: 10.2174/2211738511666230524143832

Price: $65

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Abstract

Niosomes are lipid-based nanovesicles that have the potential to act as drug-delivery vehicles for a variety of agents. They are effective drug delivery systems for both ASOs and AAV vectors, with advantages such as improved stability, bioavailability, and targeted administration. In the context of brain-targeted drug delivery, niosomes have been investigated as a drug delivery system for brain targeting, but more research is needed to optimize their formulation to improve their stability and release profile and address the challenges of scale-up and commercialization. Despite these challenges, several applications of niosomes have demonstrated the potential of novel nanocarriers for targeted drug delivery to the brain. This review briefly overviews the current use of niosomes in treating brain disorders and diseases.

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