Generic placeholder image

Current Women`s Health Reviews

Editor-in-Chief

ISSN (Print): 1573-4048
ISSN (Online): 1875-6581

Systematic Review Article

Efficacy of Homoeopathy In PCOS- A Review

Author(s): Padmalaya Rath*, Bindu Sharma, Priya Gautam and Pankhuri Misra

Volume 20, Issue 4, 2024

Published on: 19 June, 2023

Article ID: e030523216488 Pages: 14

DOI: 10.2174/1573404820666230503150406

Price: $65

Abstract

Introduction: To evaluate the usefulness of homeopathy for the treatment of PCOS through a literature review and to develop a strategy for future research.

Methods: A comprehensive search was done in electronic databases, including general medical databases MEDLINE, CENTRAL, Science Direct, specialised database for homeopathy CORE-Hom, CAM databases LILACS Chiro ACCESS, AYUSH Research Portal, Google Scholar, Research gate net, clinical trial registry, aimed to target the available literature of observational studies, randomized trials, controlled trials, case reports on PCOS in homeopathy and limited to the English language. The inclusion criteria are the studies with a full-text present in mentioned databases, studies with experimental or quasi-experimental designs published in peer-reviewed or partial peer-reviewed journals and studies with humans as their samples.

Results: A literary search through databases helped to identify a few significant studies, such as one placebo-controlled trial, one comparative clinical study, one retrospective study, three clinical studies, and nine case reports. A retrospective study showed positive results for the role of homeopathic medicines in PCOS. The placebo-controlled trial showed a difference in outcome between the two groups. The verum group showed a positive effect in the regularization of menses. The comparative clinical study showed that both homeopathic medicines (Cal. carb, Lycopodium) appeared to be effective. Three clinical studies showed the effectiveness of homeopathic medicines in improving and curing PCOS. Nine case reports showed a positive effect of homeopathy in improving PCOS, out of which three cases showed positive outcomes also in infertility with PCOS.

Conclusion: The results showed that Homoeopathy has positive effects on the management of PCOS in women. In the future, high-quality randomized controlled trials (RCT), comparative studies of homeopathy with conventional therapy, and in-vitro and animal model studies will be required to support the effectiveness of homeopathic therapeutics in PCOS.

Graphical Abstract

[1]
Teede HJ, Misso ML, Deeks AA, et al. Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline. Med J Aust 2011; 195(6): S65-S112.
[PMID: 21929505]
[2]
Roe AH, Dokras A. The diagnosis of polycystic ovary syndrome in adolescents. Rev Obstet Gynecol 2011; 4(2): 45-51.
[PMID: 22102927]
[3]
Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol 2011; 7(4): 219-31.
[http://dx.doi.org/10.1038/nrendo.2010.217] [PMID: 21263450]
[4]
Homoeopathy and yoga in the treatment of menstrual disorders in females with polycystic ovarian syndrome. Available from: https://www.cochranelibrary.com/central/doi/10.1002/central/CN01660908/full?highlightAbstract=pcos%7Chomoeopathy%7Chomoeopathi%7Chomeopathi%7Chomeopathy
[5]
Homoeopathy and yoga in the treatment of menstrual disorders in females with polycystic ovarian syndrome. 2018. Available from: https://clinicaltrials.gov/show/NCT03579303
[6]
Wiweko B, Maidarti M, Priangga MD, et al. Anti-mullerian hormone as a diagnostic and prognostic tool for PCOS patients. J Assist Reprod Genet 2014; 31(10): 1311-6.
[http://dx.doi.org/10.1007/s10815-014-0300-6] [PMID: 25119192]
[7]
Knochenhauer ES, Key TJ. Prevalence of Polycystic Ovarian Syndrome in unselected black and white women of the Southeastern United States: A prospective study. J Clin Endocrinol Metab 1998; 83: 3078-82.
[PMID: 9745406]
[8]
Farah L, Lazenby AJ, Boots LR, Azziz R. Prevalence of polycystic ovary syndrome in women seeking treatment from community electrologists. J Reprod Med 1999; 44(10): 870-4.
[PMID: 10554748]
[9]
Raja-Khan N, Stener-Victorin E, Wu X, Legro RS. The physiological basis of complementary and alternative medicines for polycystic ovary syndrome. Am J Physiol Endocrinol Metab 2011; 301(1): E1-E10.
[http://dx.doi.org/10.1152/ajpendo.00667.2010] [PMID: 21487075]
[10]
Amini L, Tehranian N, Movahedin M, Ramezani Tehrani F, Ziaee S. Antioxidants and management of polycystic ovary syndrome in Iran: A systematic review of clinical trials. Iran J Reprod Med 2015; 13(1): 1-8.
[PMID: 25653669]
[11]
Azziz R. Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: The Rotterdam criteria are premature. J Clin Endocrinol Metab 2006; 91(3): 781-5.
[http://dx.doi.org/10.1210/jc.2005-2153] [PMID: 16418211]
[12]
Higgins JPT, Altman DG, Gøtzsche PC, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 2011; 343: d5928.
[http://dx.doi.org/10.1136/bmj.d5928] [PMID: 22008217]
[13]
Burns PB, Rohrich RJ, Chung KC. The levels of evidence and their role in evidence-based medicine. Plast Reconstr Surg 2011; 128(1): 305-10.
[http://dx.doi.org/10.1097/PRS.0b013e318219c171] [PMID: 21701348]
[14]
Jonard S, Robert Y, Dewailly D. Revisiting the ovarian volume as a diagnostic criterion for polycystic ovaries. Hum Reprod 2005; 20(10): 2893-8.
[http://dx.doi.org/10.1093/humrep/dei159] [PMID: 16006474]
[15]
Oberai P, Lamba CD, Manchanda R, Rath P, Bindu H, Padmanabhan M. Evaluation of homoeopathic treatment in polycystic ovary syndrome: A single-blind, randomised, placebo-controlled pilot study. Indian J Res Homoeopathy 2018; 12(1): 35-45.
[http://dx.doi.org/10.4103/ijrh.ijrh_18_18]
[16]
Gupta G. Role of homoeopathic medicines in cases of polycystic ovarian disease assessed by modern diagnostic parameters. Adv Homeopathic Res 2017; 2: 15-25.
[17]
Malvekar PA, Nadgauda SS, Jadhav AB. A clinical study to see the effect of homoeopathic medicines in polycystic ovarian syndrome of reproductive age group between 12-45 years. Int J Health Sci Res 2020; 10(3): 43-7.
[18]
Lobo A, D'cunha P, Lobo B. Effectiveness of homoeopathic treatment in female infertility. Reprod Med Int 2018; 1: 8.
[19]
Das D, Das I, Das J, Koyal SK, Khuda-Bukhsh AR. Efficacy of two commonly used potentized homeopathic drugs, Calcarea carbonica and Lycopodium clavatum, used for treating polycystic ovarian syndrome (PCOS) patients: II. Modulating effects on certain associated hormonal levels. Cell Med 2016; 6(1): 7-1.
[20]
Thomas R. Theft of Womanhood–Polycystic Ovarian Syndrome: Role of Homeopathy. In: The Homoeopathic Heritage. 2014; pp. 41-5.
[21]
Gupta Y. Polycystic ovarian syndrome (PCOS) a case study with constitutional homoeopathic treatment. Int J Hom Sci 2019; 3(1): 22-4.
[22]
Singh R. Evidence Based treatment of polycystic ovarian syndrome/diseases (PCOS/PCOD) with homoeopathy. ACTA Sci Med Sci 2019; 3(11)
[23]
Sabharwal K, Deorukhkar TM. Ending endocrine woes: An integrated homeopathic approach to PCOS & infertility. Int J Hum Sci 2020; 4(2): 29-32.
[24]
Dabhi DP, Mathur S, Kamboj M, Jain A. Usefulness of individualised homoeopathic medicines in treatment of polycystic ovarian disease: An evidence based case series. Int J Hom Sci 2020; 4(1): 20-5.
[25]
Rath P. Management of PCOS through Homoeopathy-A case report. Indian J Res Homoeopathy 2018; 12(2): 95-100.
[http://dx.doi.org/10.4103/ijrh.ijrh_55_15]
[26]
Pal PP, Nath M. Infertility cured by dynamic potencies. Int J Res Anal Rev 2019; 6(1): 566-70.
[27]
Rath P. A case of infertility due to PCOS treated successfully with homoeopathy. Int J Hom Sci 2020; 4(2): 249-60.
[28]
Helmond W. A case of PCOS treated with homeopathy. Homoeopathic Links 2019; 32(1): 27-30.
[http://dx.doi.org/10.1055/s-0039-1687846]
[29]
Naik S. The homeopathic approach to treatment of polycystic ovarian syndrome in a rural set-up. Homeopathy 2020; 109(1): 1-28.
[http://dx.doi.org/10.1055/s-0040-1702120]
[31]
Prapas Y, Petousis S, Panagiotidis Y, et al. Injection of embryo culture supernatant to the endometrial cavity does not affect outcomes in IVF/ICSI or oocyte donation cycles: A randomized clinical trial. Eur J Obstet Gynecol Reprod Biol 2012; 162(2): 169-73.
[http://dx.doi.org/10.1016/j.ejogrb.2012.03.003] [PMID: 22464209]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy