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Infectious Disorders - Drug Targets

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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

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Case Report

Adenovirus Meningoencephalitis and Neurocysticercosis Co-infection: First Case from India

Author(s): Anju Dinkar, Jitendra Singh*, Bhavya J., Swati Singh, Nilesh Kumar and Kailash Kumar

Volume 23, Issue 5, 2023

Published on: 10 May, 2023

Article ID: e290323215132 Pages: 4

DOI: 10.2174/1871526523666230329123428

Price: $65

Abstract

Background: Adenovirus generally causes upper and lower respiratory tract infections. It is common in children and occasionally in adults. Neurological involvement is rare, which may be mild aseptic meningitis to potentially fatal acute necrotizing encephalopathy. Recently, viruses have been reported increasingly to cause CNS infections. Viral aetiology typically varies with age.

Case Presentation: Here, we report an unusual adenovirus meningoencephalitis with a co-infection of neurocysticercosis in an immunocompetent adult patient. An 18-year-old healthy female student was admitted with fever and headache for 11 days and progressive altered behaviour for 5 days, followed by altered sensorium for 3 days. This variable and unusual presentation of adenoviral infection involving CNS provoked diagnostic difficulties, but with the help of advanced diagnostics, especially molecular, exact aetiology was detected. Even with the neurocysticercosis infection in this patient, the outcome was not adversely affected.

Conclusion: This unusual co-infection with a successful outcome is the first case of this type in literature.

Graphical Abstract

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