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Current Traditional Medicine

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ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

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Review Article

Premna integrifolia: A Review on the Exploration of its Potential Pharmacological and Therapeutic Properties

Author(s): Chandrashekhar Singh, Abhishesh Kumar Mehata, Madaswamy S. Muthu and Kavindra Nath Tiwari*

Volume 10, Issue 2, 2024

Published on: 20 April, 2023

Article ID: e140323214623 Pages: 14

DOI: 10.2174/2215083809666230314154734

Price: $65

Abstract

Several Premna species can be found over the entire tropical and subtropical regions of Australia, Asia, and Africa. Many conventional herbal preparations using P. integrifolia (Lamiaceae) have been reported for their potential health advantages. The P. integrifolia is taxonomically ambiguous because of the wide variation in specimens obtained from various geographic locations. The plant is extensively used to treat immune-related disorders, skin conditions, inflammatory conditions, and stomach issues. The root of P. integrifolia is broadly utilized in the manufacture of Ayurvedic pharmaceutical products, such as Dasamula Kvatha and Chayawanprash Avaleha. It has also been identified to have antibacterial, hepatoprotective, and antifungal properties. The current study aims to investigate the antioxidant and cytotoxic activity of P. integrifolia against various cancers, as well as its antiinflammatory activity, antidiabetic, cardiac-stimulant, anti-obesity, hepatoprotective, immunomodulatory, analgesic, antiarthritic, antiparasitic, and wound healing activity, as well as the presence of various secondary metabolites in different parts of the plant used in a variety of formulations.

Graphical Abstract

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