Login Register Cart 0
Generic placeholder image

Current Women`s Health Reviews

Editor-in-Chief

ISSN (Print): 1573-4048
ISSN (Online): 1875-6581

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Predictors of Quality of Life in Women with Premature Ovarian Insufficiency

Author(s): Fatemeh Shabani, Maryam Montazeri and Mojgan Mirghafourvand*

Volume 20, Issue 2, 2024

Published on: 27 March, 2023

Article ID: e280223214162 Pages: 8

DOI: 10.2174/1573404820666230228140637

Price: $65

Abstract

Background: Women with premature ovarian insufficiency (POI) have more difficulty concerning their physical and psychological health, indicating a need to provide adequate psychosocial and clinical support for these women to minimize the repercussion of this diagnosis on their activities and quality of life.

Objective: To determine the predictors of quality of life in women with premature ovarian insufficiency (POI).

Methods: This cross-sectional study was performed on 130 women with POI in Tabriz in 2021 by convenience sampling. Data were collected using the socio-demographic characteristics questionnaire, Spielberger state-trait anxiety inventory (STAI), Beck depression scale (BDI), female sexual function index (FSFI), and the World Health Organization quality of life questionnaire (WHOQOL). The adjusted general linear model was used to estimate the impact and determine the relationship between independent variables (socio-demographic characteristics, anxiety, depression, and sexual function) and dependent variables (quality of life and its domains).

Results: The mean total score of quality of life was 46.3 (SD: 18.3) out of 0 to 100. The lowest mean score belonged to the social relations domain (35.6 (17.0)), and the highest mean score belonged to the physical health domain (40.0 (16.0)). Sexual function was one of the predictors of overall quality of life score, and all its domains except environmental health. Depression was one of the predictors of psychological health. Education was also a predictor of psychological and environmental health.

Conclusion: Sexual function and mental health are directly related to the quality of life of women with POI.

Graphical Abstract

[1]
Aminimoghaddam, S.; Norouzi, S. Ovarian failure due to cancer treatment and fertility preservation options. Tehran Univ. Med. J., 2016, 74(1), 1-8.
[2]
Izhar, R.; Husain, S.; Tahir, S.; Husain, S. Occult form of premature ovarian insufficiency in women with infertility and oligomenorrhea as assessed by poor ovarian response criteria. J. Reprod. Infertil., 2017, 18(4), 361-367.
[PMID: 29201666]
[3]
Kuang, H.; Han, D.; Xie, J.; Yan, Y.; Li, J.; Ge, P. Profiling of differentially expressed microRNAs in premature ovarian failure in an animal model. Gynecol. Endocrinol., 2014, 30(1), 57-61.
[http://dx.doi.org/10.3109/09513590.2013.850659] [PMID: 24188450]
[4]
Shareghi-oskoue, O.; Aghebati-Maleki, L.; Yousefi, M. Transplantation of human umbilical cord mesenchymal stem cells to treat premature ovarian failure. Stem Cell Res. Ther., 2021, 12(1), 454.
[http://dx.doi.org/10.1186/s13287-021-02529-w] [PMID: 34380572]
[5]
Sheikhansari, G.; Aghebati-Maleki, L.; Nouri, M.; Jadidi-Niaragh, F.; Yousefi, M. Current approaches for the treatment of premature ovarian failure with stem cell therapy. Biomed. Pharmacother., 2018, 102, 254-262.
[http://dx.doi.org/10.1016/j.biopha.2018.03.056] [PMID: 29567538]
[6]
Komorowska, B. Autoimmune premature ovarian failure. Przeglad menopauzal., 2016, 15(4), 210.
[7]
Shamilova, N.N.; Marchenko, L.A.; Dolgushina, N.V.; Zaletaev, D.V.; Sukhikh, G.T. The role of genetic and autoimmune factors in premature ovarian failure. J. Assist. Reprod. Genet., 2013, 30(5), 617-622.
[http://dx.doi.org/10.1007/s10815-013-9974-4] [PMID: 23504400]
[8]
Hadipour, F.; Hadipour, Z.; Mousavi, F.; Bagherizadeh, I.; Shafaghati, Y.; Behjati, F. Cytogenetic analysis of 13 Iranian women with premature ovarian failure. Sarem J. Reprod. Med., 2017, 2(2), 133-136.
[9]
Qin, Y.; Simpson, J.L.; Chen, Z-J. Genetics of premature ovarian failure: New developments in etiology. Karger Publishers. 2017, 21, 17-39.
[http://dx.doi.org/10.1159/000477276]
[10]
Nguyen, H.H.; Milat, F.; Vincent, A. Premature ovarian insufficiency in general practice: Meeting the needs of women. Aust. Fam. Physician, 2017, 46(6), 360-366.
[PMID: 28609590]
[11]
Tsiligiannis, S.; Panay, N.; Stevenson, J.C. Premature ovarian insufficiency and long-term health consequences. Curr. Vasc. Pharmacol., 2019, 17(6), 604-609.
[http://dx.doi.org/10.2174/1570161117666190122101611] [PMID: 30819073]
[12]
Del Mastro, L.; Ceppi, M.; Poggio, F.; Bighin, C.; Peccatori, F.; Demeestere, I.; Levaggi, A.; Giraudi, S.; Lambertini, M.; D’Alonzo, A.; Canavese, G.; Pronzato, P.; Bruzzi, P. Gonadotropin-releasing hormone analogues for the prevention of chemotherapy-induced premature ovarian failure in cancer women: Systematic review and meta-analysis of randomized trials. Cancer Treat. Rev., 2014, 40(5), 675-683.
[http://dx.doi.org/10.1016/j.ctrv.2013.12.001] [PMID: 24360817]
[13]
Benetti-Pinto, C.L.; Soares, P.M.; Giraldo, H.P.D.; Yela, D.A. Role of the different sexuality domains on the sexual function of women with premature ovarian failure. J. Sex. Med., 2015, 12(3), 685-689.
[http://dx.doi.org/10.1111/jsm.12743] [PMID: 25377950]
[14]
Bueno de Almeida, D.M.; Benetti-Pinto, C.L.; Makuch, M.Y. Sexual function of women with premature ovarian failure. Menopause, 2011, 18(3), 262-266.
[http://dx.doi.org/10.1097/gme.0b013e3181f4318d] [PMID: 21127440]
[15]
Nappi, R.E.; Cucinella, L.; Martini, E.; Rossi, M.; Tiranini, L.; Martella, S.; Bosoni, D.; Cassani, C. Sexuality in premature ovarian insufficiency. Climacteric, 2019, 22(3), 289-295.
[http://dx.doi.org/10.1080/13697137.2019.1575356] [PMID: 30900474]
[16]
Eden, K.J.; Wylie, K.R. Quality of sexual life and menopause. Womens Health, 2009, 5(4), 385-396.
[http://dx.doi.org/10.2217/WHE.09.24] [PMID: 19586430]
[17]
Groff, A.A.; Covington, S.N.; Halverson, L.R.; Fitzgerald, O.R.; Vanderhoof, V.; Calis, K.; Nelson, L.M. Assessing the emotional needs of women with spontaneous premature ovarian failure. Fertil. Steril., 2005, 83(6), 1734-1741.
[http://dx.doi.org/10.1016/j.fertnstert.2004.11.067] [PMID: 15950644]
[18]
van der Stege, J.G.; Groen, H.; van Zadelhoff, S.J.N.; Lambalk, C.B.; Braat, D.D.M.; van Kasteren, Y.M.; van Santbrink, E.J.P.; Apperloo, M.J.A.; Weijmar Schultz, W.C.M.; Hoek, A. Decreased androgen concentrations and diminished general and sexual well-being in women with premature ovarian failure. Menopause, 2008, 15(1), 23-31.
[http://dx.doi.org/10.1097/gme.0b013e3180f6108c] [PMID: 18257141]
[19]
Benetti-Pinto, C.L.; de Almeida, D.M.B.; Makuch, M.Y. Quality of life in women with premature ovarian failure. Gynecol. Endocrinol., 2011, 27(9), 645-649.
[http://dx.doi.org/10.3109/09513590.2010.520374] [PMID: 21214499]
[20]
Group, W. Development of the WHOQOL. Int. J. Ment. Health, 1994, 23(3), 24-56.
[21]
Li, X.T.; Li, P.Y.; Liu, Y.; Yang, H.S.; He, L.Y.; Fang, Y.G.; Liu, J.; Liu, B.Y.; Chaplin, J.E. Health-related quality-of-life among patients with premature ovarian insufficiency: A systematic review and meta-analysis. Qual. Life Res., 2020, 29(1), 19-36.
[http://dx.doi.org/10.1007/s11136-019-02326-2] [PMID: 31620985]
[22]
Sadeghi, S. Standardization spielberger test.MA thesis. Tehran: Islamic Azad University, 2002.
[23]
Julian, LJ Measures of anxiety.Arthritics. Care. Res., 2011, 63(011)
[24]
Rahimi, C. Application of the beck depression inventory-II in Iranian University students. Clinic. Psychol. Personal., 2014, 12(1), 173-188.
[25]
Mohammadi, K.; Heydari, M.; Faghihzadeh, S. The female sexual function index (FSFI): Validation of the Iranian version. J. Payesh., 2008, 7(3), 269-278.
[26]
Skevington, S.M.; Lotfy, M.; O’Connell, K.A. The World Health Organization’s WHOQOL-BREF quality of life assessment: Psychometric properties and results of the international field trial. A Report from the WHOQOL Group. Qual. Life Res., 2004, 13(2), 299-310.
[http://dx.doi.org/10.1023/B:QURE.0000018486.91360.00] [PMID: 15085902]
[27]
Nejat, S.; Montazeri, A.; Holakouie Naieni, K.; Mohammad, K.; Majdzadeh, S. The World Health Organization quality of Life (WHOQOL-BREF) questionnaire: Translation and validation study of the Iranian version. J. Public Health Res., 2006, 4(4), 1-12.
[28]
Martin, C.M.; Larroy, C. López-Picado, A.; Fernández-Arias, I. Accuracy of the menopause rating scale and the menopause quality of life questionnaire to discriminate menopausal women with anxiety and depression. Menopause, 2019, 26(8), 856-862.
[http://dx.doi.org/10.1097/GME.0000000000001338] [PMID: 31124913]
[29]
Sánchez-Rodríguez, M.A.; Castrejón-Delgado, L.; Zacarías-Flores, M.; Arronte-Rosales, A.; Mendoza-Núñez, V.M. Quality of life among post-menopausal women due to oxidative stress boosted by dysthymia and anxiety. BMC Womens Health, 2017, 17(1), 1-9.
[http://dx.doi.org/10.1186/s12905-016-0358-7] [PMID: 28049464]
[30]
Rosenberg, S.M.; Tamimi, R.M.; Gelber, S.; Ruddy, K.J.; Kereakoglow, S.; Borges, V.F.; Come, S.E.; Schapira, L.; Winer, E.P.; Partridge, A.H. Body image in recently diagnosed young women with early breast cancer. Psychooncology, 2013, 22(8), 1849-1855.
[http://dx.doi.org/10.1002/pon.3221] [PMID: 23132765]
[31]
Salci, L.E.; Martin Ginis, K.A. Acute effects of exercise on women with pre-existing body image concerns: A test of potential mediators. Psychol. Sport Exerc., 2017, 31, 113-122.
[http://dx.doi.org/10.1016/j.psychsport.2017.04.001]
[32]
Javadpour, S.; Sharifi, N.; Mosallanezhad, Z.; Rasekhjahromi, A.; Jamali, S. Assessment of premature menopause on the sexual function and quality of life in women. Gynecol. Endocrinol., 2021, 37(4), 307-311.
[http://dx.doi.org/10.1080/09513590.2021.1871894] [PMID: 33432868]
[33]
Yela, D.; Soares, P.; Benetti-Pinto, C. Influence of sexual function on the social relations and quality of life of women with premature ovarian insufficiency. Rev. Bras. Ginecol. Obstet., 2018, 40(2), 066-071.
[http://dx.doi.org/10.1055/s-0037-1615289] [PMID: 29490412]
[34]
Zhou, E.S.; Falk, S.J.; Bober, S.L. Managing premature menopause and sexual dysfunction. Curr. Opin. Support. Palliat. Care, 2015, 9(3), 294-300.
[http://dx.doi.org/10.1097/SPC.0000000000000156] [PMID: 26155020]
[35]
Park, H.; Yoon, H.G. Menopausal symptoms, sexual function, depression, and quality of life in Korean patients with breast cancer receiving chemotherapy. Support. Care Cancer, 2013, 21(9), 2499-2507.
[http://dx.doi.org/10.1007/s00520-013-1815-6] [PMID: 23616110]
[36]
Han, J.A.; Choi, S.Y.; Lee, S. Effects of menopausal symptoms and depression on the quality of life of premenopausal women with breast cancer in Korea. J. Transcult. Nurs., 2019, 30(1), 8-16.
[http://dx.doi.org/10.1177/1043659618771475] [PMID: 29690858]
[37]
Wariso, B.A.; Guerrieri, G.M.; Thompson, K.; Koziol, D.E.; Haq, N.; Martinez, P.E.; Rubinow, D.R.; Schmidt, P.J. Depression during the menopause transition: Impact on quality of life, social adjustment, and disability. Arch. Women Ment. Health, 2017, 20(2), 273-282.
[http://dx.doi.org/10.1007/s00737-016-0701-x] [PMID: 28000061]
[38]
Fallahzadeh, H. Quality of life after the menopause in Iran: A population study. Qual. Life Res., 2010, 19(6), 813-819.
[http://dx.doi.org/10.1007/s11136-010-9644-2] [PMID: 20358299]
[39]
Wen, J.; Shi, Y.; Li, Y.; Yuan, P.; Wang, F. Quality of life, physical diseases, and psychological impairment among survivors 3 years after Wenchuan earthquake: A population based survey. PLoS One, 2012, 7(8), e43081.
[http://dx.doi.org/10.1371/journal.pone.0043081] [PMID: 22937014]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy