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Current Organocatalysis

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ISSN (Print): 2213-3372
ISSN (Online): 2213-3380

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Short Communication

Stereospecific Total Synthesis of Putaminoxin 1 by Ring Closing Metathesis and Enantioselective Epoxidation

Author(s): Vanam Shekhar*, Chithaluri Sudhakar* and Nagireddy Veerareddy

Volume 10, Issue 2, 2023

Published on: 18 May, 2023

Page: [128 - 132] Pages: 5

DOI: 10.2174/2213337210666230228105711

Price: $65

Abstract

The stereoselective synthesis of putaminoxin 1, a biologically active natural phototoxic lactone has been synthesized from (R)-2-Propyloxirane and Hex-5-en-1-ol. The synthesis involves Jacobsen’s hydrolytic kinetic resolution and ring-closing metathesis as the key steps.

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