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Current Nanoscience

Editor-in-Chief

ISSN (Print): 1573-4137
ISSN (Online): 1875-6786

Research Article

Preparation of Ampicillin-derived CQDs and its Application in the Detection of Phenols in Medicinal Materials

Author(s): Yu Zhang* and Ping Zhang

Volume 20, Issue 2, 2024

Published on: 11 April, 2023

Page: [264 - 271] Pages: 8

DOI: 10.2174/1573413719666230222124501

Price: $65

Abstract

Background: In this study, ampicillin sodium fluorescent carbon quantum dots were prepared by one-step hydrothermal method with ampicillin sodium as the carbon source and urea as the nitrogen source.

Methods: The structure of CQDs were characterized by UV-Vis and fluorescence spectrophotometer. The pH, reaction time and ionic strength of phenol detected by N-CQDs were optimized. The optimum experimental conditions were 40 μL ampicillin sodium N-CQDs, 2 mL buffer solution with pH 8.0, and the reaction time was 6 min.

Results: Through the detection of fluorescence spectrophotometry, p-nitrophenol had obvious fluorescence quenching phenomenon on ampicillin sodium N-CQDs, and the detection limit was 75 nM. It was used in the standard addition experiment of actual samples, and the recovery rates were more than 85%.

Conclusion: Therefore, the N-CQDs could be used as fluorescent probe to analyze the content of p-nitrophenol in the actual environment.

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