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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Editorial

Challenges and Discoveries in Polypharmacology

Author(s): Marcus T. Scotti and Luciana Scotti

Volume 23, Issue 5, 2023

Published on: 17 February, 2023

Page: [331 - 333] Pages: 3

DOI: 10.2174/156802662305230217155933

Price: $65

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[1]
Lorenzo, V. P.; Lucio, A.; Scotti, L.; Tavares, J. F.; Barbosa, J. M.; Lima, T. K. D.; Rocha, J. D.; Scotti, M. T. Structure- and Ligand-Based Approaches to Evaluate Aporphynic Alkaloids from Annonaceae as Multi-Target Agent Against Leishmania donovani. Current Pharmaceutical Design, 2016, 22(34), 5196-5203.
[http://dx.doi.org/10.2174/1381612822666160513144853]
[2]
Luis, J. A. D.; Costa, N. A. D.; Luis, C. C. S.; Lira, B. F.; Athayde, P. F.; Lima, T. K. D.; Rocha, J. C.; Scotti, L.; Scotti, M. T. Synthesis of New Cyclic Imides Derived from Safrole, Structure- and Ligand-based Approaches to Evaluate Potential New Multitarget Agents Against Species of Leishmania. Medicinal Chemistry, 2020, 16(1), 39-51.
[http://dx.doi.org/10.2174/1573406415666190430144950]
[3]
Luis, J. A. D.; Souza, H. D. D.; Lira, B. F.; Alves, F. D.; de Athayde, P. F.; Lima, T. K. D.; Rocha, J. C.; Mendonca, F. J. B.; Scotti, L.; Scotti, M. T. Combined structure- and ligand-based virtual screening aiding discovery of selenoglycolicamides as potential multitarget agents against Leishmania species. Journal of Molecular Structure, 2019, 1198.
[http://dx.doi.org/10.1016/j.molstruc.2019.126872]
[4]
Maia, M. D.; Rodrigues, G. C. S.; de Sousa, N. F.; Scotti, M. T.; Scotti, L.; Mendonca, F. J. B. Identification of New Targets and the Virtual Screening of Lignans against Alzheimer's Disease. Oxidative Medicine and Cellular Longevity, 2020, 2020
[http://dx.doi.org/10.1155/2020/3098673]
[5]
Maia, M. D.; Silva, J. P. E.; Nunes, T. A. D.; de Sousa, J. M. S.; Rodrigues, G. C. S.; Monteiro, A. F. M.; Tavares, J. F.; Rodrigues, K. A. D.; Mendonca, F. J. B.; Scotti, L.; et al. Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans. Molecules, 2020, 25(10)
[http://dx.doi.org/10.3390/molecules25102281]
[6]
Pedrosa, M. D.; da Cruz, R. M. D.; Viana, J. D.; de Moura, R. O.; Ishiki, H. M.; Barbosa, J. M.; Diniz, M.; Scotti, M. T.; Scotti, L.; Mendonca, F. J. B. Hybrid Compounds as Direct Multitarget Ligands: A Review. Current Topics in Medicinal Chemistry, 2017, 17(9), 1044-1079.
[http://dx.doi.org/10.2174/1568026616666160927160620]
[7]
Putta, S.; Yarla, N. S.; Peluso, I.; Tiwari, D. K.; Reddy, G.; Giri, P. V.; Kumar, N.; Malla, R.; Rachel, V.; Bramhachari, P. V.; et al. Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases. Current Pharmaceutical Design, 2017, 23(41), 6321-6346.
[http://dx.doi.org/10.2174/1381612823666170519151801]
[8]
Scotti, L.; Filho, F.; de Moura, R. O.; Ribeiro, F. F.; Ishiki, H.; da Silva, M. S.; Filho, J. M. B.; Scotti, M. T. Multi-Target Drugs for Neglected Diseases. Current Pharmaceutical Design, 2016, 22(21), 3135-3163.
[http://dx.doi.org/10.2174/1381612822666160224142552]
[9]
Scotti, L.; Mendonca, F. J. B.; Moreira, D. R. M.; da Silva, M. S.; Pitta, I. R.; Scotti, M. T. SAR, QSAR and Docking of Anticancer Flavonoids and Variants: A Review. Current Topics in Medicinal Chemistry, 2012, 12(24), 2785-2809.
[10]
Scotti, L.; Mendonca, F. J. B.; Scotti, M. T. Hybrid Compounds as Multitarget Agents in Medicinal Chemistry - Part I. Current Topics in Medicinal Chemistry, 2017, 17(8), 843-844.
[http://dx.doi.org/10.2174/156802661708170126200430]

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