Diffuse Large B-cell Lymphoma Presenting as an “Oops” Lesion in the
Nasolabial Fold: A Case Report

Young   Jin   Heo; Hye   Jin   Baek; Yoon   Jung   Lee; Hyun   Min   Koh

doi:10.2174/1573405619666221125143942

Abstract

Background: Diffuse large B-cell lymphomas are the most common type of non-Hodgkin lymphoma. Because cutaneous lymphomas predominantly originate from the T cells, primary cutaneous diffuse large B-cell lymphomas are considered a rare subtype of extranodal diffuse large B-cell lymphomas that commonly involve the subcutaneous tissues of the trunk and extremities. To date, only a single case of facial primary cutaneous diffuse large B-cell lymphoma has been reported in the literature.

Case Report: We present a case of primary cutaneous diffuse large B-cell lymphoma presented with a small painless nodule in the right nasolabial fold that had persisted for 10 days in a 67-year-old man. Ultrasonographic findings of this lesion mimicked the features of a complicated epidermal inclusion cyst. Primary cutaneous diffuse large B-cell lymphoma was confirmed by an excisional biopsy of the mass.

Conclusion: The diagnosis of primary cutaneous diffuse large B-cell lymphomas presenting as “oops lesions” in daily clinical practice can be challenging due to their rarity and nonspecific clinical and radiological findings. Therefore, clinical suspicion and awareness are critical for the accurate diagnosis and management of patients with palpable soft tissue masses in the head and neck region.

Graphical Abstract

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DOI https://dx.doi.org/10.2174/1573405619666221125143942	Print ISSN 1573-4056
Publisher Name Bentham Science Publisher	Online ISSN 1875-6603

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Diffuse Large B-cell Lymphoma Presenting as an “Oops” Lesion in the Nasolabial Fold: A Case Report

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