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Anti-Cancer Agents in Medicinal Chemistry

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ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

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Mini-Review Article

The Postulated Mechanism of Action of Amygdalin (Vitamin B17) on Cancer Cells

Author(s): Mohamed Ali El-Desouky, Abdelgawad Ali Fahmi* and Karima Mahmoud Nasraldin

Volume 23, Issue 8, 2023

Published on: 26 December, 2022

Page: [894 - 899] Pages: 6

DOI: 10.2174/1871520623666221124143751

Price: $65

Abstract

The current study demonstrates amygdalin’s (vitamin B17) postulated mechanism of action on cancer cells where it kills cells by selective toxicity, promotes apoptosis via cell cycle arrest, induces apoptosis via intrinsic cell death pathway (the mitochondria-initiated pathway), and enhances immunity. Thus, amygdalin can be considered a valuable natural cancer therapeutic agent. The toxicity of Amygdalin was reviewed. Moreover, solutions to avoid the cyanide poisoning have been proposed.

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