Login Register Cart 0
Generic placeholder image

Infectious Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Case Report

Disseminated Tuberculosis in an Immunocompetent State: A Case Report

Author(s): Jitendra Singh, Anju Dinkar*, Nitish Kumar Patel, Bhavya J, Ankita Dewangan, Nilesh Kumar and Kalish Kumar

Volume 23, Issue 2, 2023

Published on: 13 October, 2022

Article ID: e210922209022 Pages: 5

DOI: 10.2174/1871526522666220921123920

Price: $65

Abstract

Background: Tuberculosis is one of the major infectious diseases of mankind and remains a significant health concern, especially in developing countries. Clinical manifestations of TB are broad and sometimes very challenging for clinicians to diagnose early. Tuberculous psoas abscess was generally secondary to spinal tuberculosis or direct extension from adjacent structures in immunocompromised individuals, but tuberculous psoas abscess in the immunocompetent state is very infrequent. In addition, pancytopenia and new onset neck swelling simultaneously make this presentation a very unusual clinical entity in tuberculosis.

Case Presentation: We now present a case of a 21-years-old, unmarried, otherwise healthy girl presented with fever, lower abdominal pain and weight loss for two months. She also noticed painless neck swelling for 15 days. She later had a tuberculous left sided psoas abscess with pancytopenia and a cold abscess on the left side of the neck with no sign of any other apparent focus, according to the evidence. Diagnosis of disseminated TB without lung involvement was established and ATT was started. The outcome was successful on follow up.

Conclusion: Among the broad spectrum of atypical manifestations of TB, this case report draws attention to its rarity, diagnostic challenge and awareness of the clinical spectrum, especially in developing countries.

Keywords: Pott’s spine, psoas abscess, pancytopenia, cold abscess, neck swelling

Graphical Abstract

[1]
Dinkar A, Singh J. Positive outcome of pulmonary tuberculosis associated with extraordinary extensive extrapulmonary tuberculosis in an immunocompetent adult. Int J Mycobacteriol 2018; 7(2): 183-5.
[http://dx.doi.org/10.4103/ijmy.ijmy_61_18] [PMID: 29900898]
[2]
WHO. Global tuberculosis report 2021. Available from: https://www.who.int/news-room/fact-sheets/detail/tuberculosis [Accessed: December 29, 2021].
[3]
Singh J, Dinkar A, Gupta P. Uncommon manifestations in tuberculosis: An expanding clinical spectrum from North India. Int J Mycobacteriol 2022; 11(1): 30-7.
[http://dx.doi.org/10.4103/ijmy.ijmy_242_21] [PMID: 35295021]
[4]
Ndjoubi KO, Sharma R, Hussein AA. The potential of natural diterpenes against tuberculosis: An updated review. Curr Pharm Des 2020; 26(24): 2909-32.
[http://dx.doi.org/10.2174/1381612826666200612163326] [PMID: 32532186]
[5]
Ordonez AA, Maiga M, Gupta S, Weinstein EA, Bishai WR, Jain SK. Novel adjunctive therapies for the treatment of tuberculosis. Curr Mol Med 2014; 14(3): 385-95.
[http://dx.doi.org/10.2174/1566524013666131118112431] [PMID: 24236454]
[6]
Akhaddar A, Hall W, Ramraoui M, Nabil M, Elkhader A. Primary tuberculous psoas abscess as a postpartum complication: Case report and literature review. Surg Neurol Int 2018; 9(1): 239.
[http://dx.doi.org/10.4103/sni.sni_329_18] [PMID: 30595960]
[7]
Mellat-Ardakani M, Ghiasvand F, Nezhad MH, Salahshour F. SeyedAlinaghi S. Multifocal osteolytic lesions in skull bone with Mycobacterium tuberculosis: A case report. Infect Disord Drug Targets 2021; 21(5): e270421187878.
[http://dx.doi.org/10.2174/1871526520999201111200140] [PMID: 33183211]
[8]
Bagir M, Sayit E. Tuberculous tenosynovitis of the wrist: A report of two cases with special reference to magnetic resonance findings. Curr Med Imaging Rev 2019; 15(5): 517-20.
[http://dx.doi.org/10.2174/1573405614666180919141141] [PMID: 32008560]
[9]
Kpodonu J, Cook J, Massad M, Snow N. Tuberculosis of the thymus: A case report and review of the literature. Curr Respir Med Rev 2005; 1(2): 123-6.
[http://dx.doi.org/10.2174/1573398054023028]
[10]
Singh J, Dinkar A, Vardan A, Gupta KK, Patel ML, Sahani KK. Chylous ascites in disseminated Tuberculosis; A rare case report. Adv Biores 2015; 6(6): 154-7.
[http://dx.doi.org/10.15515/abr.0976-4585.6.6.154157]
[11]
Mynter H. Acute psoitis. Buffalo Med Surg J 1881; 21: 202-10.
[12]
Chawla K, D’Souza A, Shyamasunder BN, Mukhopadhayay C. Primary tubercular psoas abscess: A rare presentation. J Infect Dev Ctries 2011; 6(1): 86-8.
[http://dx.doi.org/10.3855/jidc.2070] [PMID: 22240434]
[13]
Adelekan MO, Taiwo SS, Onile BA. A review of psoas abscess. Afr J Clin Exp Microbiol 2004; 5(1): 55-63.
[http://dx.doi.org/10.4314/ajcem.v5i1.7360]
[14]
Vaz AP, Gomes J, Esteves J, Carvalho A, Duarte R. A rare cause of lower abdominal and pelvic mass, primary tuberculous psoas abscess: A case report. Cases J 2009; 2(1): 182.
[http://dx.doi.org/10.1186/1757-1626-2-182] [PMID: 19946492]
[15]
Cano C, Alconada RG, Borobio G, et al. A rare cause of hip pain: Primary tuberculous psoas abscess. Case Report JSM Clin Case Rep 2015; 3(2): 1078.
[16]
Açar P, Ziyadanoglu P, Kula AC, Ataoğlu HE. Isolated psoas abscess due to Mycobacterium tuberculosis. IJCMR 2020; 7(7): G1-2.
[http://dx.doi.org/10.21276/ijcmr.2020.7.7.13]
[17]
Wang JY, Hsueh PR, Wang SK, et al. Disseminated tuberculosis. Medicine (Baltimore) 2007; 86(1): 39-46.
[http://dx.doi.org/10.1097/MD.0b013e318030b605] [PMID: 17220754]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy