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Endocrine, Metabolic & Immune Disorders - Drug Targets

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Research Article

Comparative Study on Clinical Characteristics of COVID-19 Patients with or without Digestive Symptoms in Razi Hospital, Ahvaz, Khuzestan

Author(s): Reza Khedri, Hossein Bahrami Moghadam, Wesam Kooti, Ali Delirrooyfard*, Payam Amini, Mahmood Maniati, Vahid Garmsiri, Mahsa Tabibi, Leila Jalalian, Mahsan Nouri, Seyed Saeed Seyedian, Kambiz Masoumi and Keramat Javdanzadeh

Volume 23, Issue 5, 2023

Published on: 19 December, 2022

Page: [647 - 671] Pages: 25

DOI: 10.2174/1871530322666220823155956

Price: $65

Abstract

Background: Most commonly reported clinical manifestations are fever, fatigue and dry cough. Interestingly, a small percentage of patients experience GI symptoms, with the most common being anorexia, diarrhea, nausea and vomiting. We aimed to conduct a comparative study on COVID-19 patients with or without gastrointestinal patients (GI).

Aims: The pandemic of coronavirus disease 2019 (COVID-19) has emerged as a dire health problem, causing a massive crisis for global health.

Methods: Collective data of clinical manifestations and laboratory reports of patients admitted to Razi Hospital, Ahvaz, Khuzestan, Iran, for two weeks were analyzed.

Results: Our results showed that GI symptoms are not statistically significant criteria to be predictive or prognostic factors in COVID-19 patients, although they are probably related to the acute or non-acute phase of the disease. Moreover, non-specific GI symptoms seem to result from cytokine storm that occurred during the disease.

Conclusion: Therefore, our results did not support GI tract involvement as a common route of COVID- 19 infection. Maybe future research will shed light on why and how the gastrointestinal system becomes infected by COVID-19.

Keywords: COVID-19, Gastrointestinal, Diabetes, Cytokine, Fever

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