Abstract
Background: Takotsubo cardiomyopathy is characterized by transient regional ventricular abnormalities in the absence of coronary artery disease and is reported as a complication of COVID-19.
Case Presentation: It can have a diverse clinical presentation, occasionally resembling an acute coronary syndrome, and progress to acute heart failure and cardiogenic shock, adversely affecting patients' prognosis. A high index of suspicion and a thorough diagnostic approach supported by ancillary studies like echocardiography and coronary angiography is key for an accurate diagnosis and correct medical treatment. Herein, we report a patient with severe COVID-19 who developed Takotsubo cardiomyopathy.
Conclusion: We also present a detailed literature review regarding the relationship between COVID-19 and Takotsubo cardiomyopathy.
Keywords: Takotsubo cardiomyopathy, Stress cardiomyopathy, Apical ballooning syndrome, COVID-19, SARS-CoV-2 infection, Cardiogenic Shock, Heart Failure
Graphical Abstract
[http://dx.doi.org/10.1056/NEJMcp2009575] [PMID: 32412710]
[http://dx.doi.org/10.1161/CIRCRESAHA.120.317055] [PMID: 32252591]
[http://dx.doi.org/10.1016/j.hlc.2021.02.004] [PMID: 33715970]
[http://dx.doi.org/10.1093/ehjci/jeaa236] [PMID: 32949135]
[http://dx.doi.org/10.1038/s41569-020-0413-9] [PMID: 32690910]
[PMID: 33758123]
[http://dx.doi.org/10.1161/CIRCRESAHA.121.317997] [PMID: 33856918]
[http://dx.doi.org/10.1016/S0140-6736(20)30183-5] [PMID: 31986264]
[http://dx.doi.org/10.1001/jama.2020.1585] [PMID: 32031570]
[http://dx.doi.org/10.1016/S0140-6736(20)30566-3] [PMID: 32171076]
[http://dx.doi.org/10.1056/NEJMoa2002032] [PMID: 32109013]
[http://dx.doi.org/10.1001/jama.2020.2648] [PMID: 32091533]
[http://dx.doi.org/10.1007/s00134-020-05991-x] [PMID: 32125452]
[http://dx.doi.org/10.1001/jama.2020.5394] [PMID: 32250385]
[http://dx.doi.org/10.1056/NEJMc2010419] [PMID: 32302078]
[http://dx.doi.org/10.1001/jama.2020.6775] [PMID: 32320003]
[http://dx.doi.org/10.1093/eurheartj/ehy076] [PMID: 29850871]
[http://dx.doi.org/10.1056/NEJMoa1406761] [PMID: 26332547]
[http://dx.doi.org/10.1001/jamanetworkopen.2020.14780] [PMID: 32644140]
[http://dx.doi.org/10.1093/eurheartj/ehaa306] [PMID: 32285915]
[http://dx.doi.org/10.1016/j.jaccas.2020.04.009] [PMID: 32328588]
[http://dx.doi.org/10.1016/j.jaccas.2020.04.023] [PMID: 32363351]
[http://dx.doi.org/10.1093/ehjci/jeaa152] [PMID: 32395765]
[http://dx.doi.org/10.1714/3359.33323] [PMID: 32425184]
[http://dx.doi.org/10.12890/2020_001665] [PMID: 32399453]
[http://dx.doi.org/10.1016/j.jacc.2020.05.068] [PMID: 32517962]
[http://dx.doi.org/10.1136/bcr-2020-236561] [PMID: 32540884]
[http://dx.doi.org/10.12691/ajmcr-8-10-8] [PMID: 32704530]
[http://dx.doi.org/10.1093/eurheartj/ehaa390] [PMID: 32391885]
[http://dx.doi.org/10.1016/j.ijcha.2020.100580] [PMID: 32685662]
[http://dx.doi.org/10.1161/CIRCIMAGING.120.011222] [PMID: 32673494]
[http://dx.doi.org/10.1093/ehjci/jeaa178] [PMID: 32556199]
[PMID: 32523926]
[http://dx.doi.org/10.1093/eurheartj/ehaa286] [PMID: 32267502]
[http://dx.doi.org/10.1186/s12872-020-01665-0] [PMID: 32842957]
[http://dx.doi.org/10.1016/j.carpath.2020.107314] [PMID: 33259936]
[http://dx.doi.org/10.1093/ehjcr/ytaa271] [PMID: 33437922]
[http://dx.doi.org/10.1136/openhrt-2020-001360] [PMID: 33020258]
[http://dx.doi.org/10.1002/ehf2.12912] [PMID: 32886428]
[http://dx.doi.org/10.1136/bcr-2020-236811] [PMID: 33310830]
[http://dx.doi.org/10.1016/j.jaccas.2020.06.008] [PMID: 32835280]
[http://dx.doi.org/10.7759/cureus.11296] [PMID: 33282573]
[http://dx.doi.org/10.1016/j.jccase.2020.11.017] [PMID: 33262862]
[http://dx.doi.org/10.1016/j.carrev.2021.01.017] [PMID: 33516638]
[http://dx.doi.org/10.1016/j.rec.2020.04.012] [PMID: 32499016]
[http://dx.doi.org/10.1093/ehjcr/ytaa188] [PMID: 33089052]
[http://dx.doi.org/10.1155/2020/8842150] [PMID: 32934848]
[http://dx.doi.org/10.1016/j.amjms.2021.01.024] [PMID: 34446260]
[http://dx.doi.org/10.2217/fca-2020-0115] [PMID: 33078963]
[http://dx.doi.org/10.1136/bcr-2020-239104] [PMID: 32988978]
[http://dx.doi.org/10.7759/cureus.18693] [PMID: 34659930]
[http://dx.doi.org/10.1007/s42399-020-00683-5] [PMID: 33426474]
[http://dx.doi.org/10.36660/ijcs.20200398]
[http://dx.doi.org/10.32291/nmj.3.0_1]
[http://dx.doi.org/10.1016/j.jacc.2020.10.060] [PMID: 33602474]
[PMID: 32341693]
[http://dx.doi.org/10.1093/eurheartj/ehl032] [PMID: 16720686]
[http://dx.doi.org/10.1007/s42399-020-00557-w] [PMID: 33043251]
[http://dx.doi.org/10.1093/eurheartj/ehy077] [PMID: 29850820]
[http://dx.doi.org/10.1001/jama.2021.19608] [PMID: 34714324]
[http://dx.doi.org/10.1056/NEJMoa2034577] [PMID: 33301246]
[http://dx.doi.org/10.1016/j.jccase.2021.08.012] [PMID: 34539938]
[PMID: 34731486]