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Current Medical Imaging

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ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

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Case Report

A Case of Intracranial Space-occupying Lesion Caused by Infection of AIDS-associated Talaromyces Marnefei

Author(s): Shuyi Xie, Lieguang Zhang, Deyang Huang, Yanhong Yang, Zhiping Zhang, Yanhua Xiao, Xiaoping Tang* and Jinxin Liu*

Volume 19, Issue 8, 2023

Published on: 01 September, 2022

Article ID: e110822207407 Pages: 7

DOI: 10.2174/1573405618666220811120308

Price: $65

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Abstract

Background: Talaromyces marneffei (T. marneffei) is a heat-dimorphic fungus that commonly causes fatal opportunistic infections in immunocompromised patients, such as those with human immunodeficiency virus (HIV) infection.

Case Presentation: In this case report we describe a case of intracranial infection of T. marneffei in a 42-year-old AIDS patient. Contrast enhanced MRI showed the left occipital lobe mass with ring enhancement, MRS showed elevated AAs and Lip waves in the mass. Surgical resection of the occipital lobe confirmed the lesion to be T. marneffei infection and possibly with tuberculosis after a pathological examination. Patients with intracranial ring enhancing space-occupying lesions on MRI should be considered for intracranial T. marneffei infection. Intracranial T. marneffei infection is relatively rarely reported and recently studied.

Conclusion: The MRI, in this case, suggests that ring enhancement mass and elevated AAs and Lip waves are helpful in the diagnosis of T. marneffei infection.

Keywords: Talaromyces marneffei, Intracranial infection, Magnetic resonance imaging.

Graphical Abstract

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