Generic placeholder image

Current Traditional Medicine

Editor-in-Chief

ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

Review Article

Dolichos biflorus, Useful Food for Patients with Kidney Stones

Author(s): Mohammad Azad Manjiri, Amir Abbas Asadpour, Mahdi Yousefi, Seyed Majid Ghazanfari and Roshanak Salari*

Volume 9, Issue 2, 2023

Published on: 19 September, 2022

Article ID: e040822207293 Pages: 7

DOI: 10.2174/2215083808666220804160620

Price: $65

Abstract

Urolithiasis is a common problem worldwide manifested with recurrent intermittent pain episodes, which today is increasing due to changes in lifestyle patterns, including sedentary and consumption of protein, fat, and fiber-free foods, as well as stress. Today, the role of nutrition in the formation of kidney stones as well as in its prevention is recognized as a key factor. Dolichos biflorus is one of the most famous plants that are known as a useful food in the prevention and treatment of kidney stones. In this review study, electronic databases of PubMed, Scopus, Cochrane, Google Scholar, and Web of science and Persian medicinal books such as Al- Hawi, Al-Shamel fi-Alsenaat Altebbiah, Makhzan-al-Advia, and Tohfat al Momenin were searched to identify all the studies reporting the effects of Dolichos biflorus on kidney stones.

Dolichos biflorus seeds contain effective substances in preventing kidney stone formation. These substances include Citrate, Magnesium, Potassium, and Vitamin B6. A protein has been identified in Dolichos biflorus grain that has antiseptic and inhibitory stone formation properties. In several studies, the effect of Dolichos biflorus extract on the dissolution of kidney stones and their prevention has been investigated.

Dolichos biflorus seeds can be used as a useful and effective food in patients with kidney stones, in addition to its nutritional role, as a harmless drug to prevent stone production.

Keywords: Dolichos Biflorus, complementary and alternative medicine, kidney stone, persian medicine, urolithiasis, vitamin B6 [Pyridoxine].

Graphical Abstract

[1]
McAninch JW, Lue TF. Smith & Tanagho's General Urology. New York: McGraw-Hill Medical 2013.
[2]
Prezioso D, Strazzullo P, Lotti T, et al. Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group. Archivio Italiano di Urologia 2015; 87(2): 105-20.
[3]
Ahmed S, Hasan MM, Mahmood ZA. Macrotyloma uniflorum [Lam. Verdc. [Papilionaceae]: A review of medicinal uses, phytochemistry, and pharmacology. WJPPS 2016; 5(2): 51-62.
[4]
Aggarwal A, Tandon S, Singla SK, Tandon C. Diminution of oxalate induced renal tubular epithelial cell injury and inhibition of calcium oxalate crystallization in vitro by aqueous extract of Tribulus terrestris. Int Braz J Urol 2010; 36(4): 480-8.
[http://dx.doi.org/10.1590/S1677-55382010000400011]
[5]
Baumann JM. Stone prevention: Why so little progress? Urol Res 1998; 26(2): 77-81.
[http://dx.doi.org/10.1007/s002400050027] [PMID: 9631938]
[6]
Saha S, Verma RJ. Antinephrolithiatic and antioxidative efficacy of Dolichos biflorus seeds in a lithiasic rat model. Pharm Biol 2015; 53(1): 16-30.
[http://dx.doi.org/10.3109/13880209.2014.909501] [PMID: 25243879]
[7]
Baynes R, Riviere J. Risks associated with melamine and related triazine contamination of food. Emerg Health Threats J 2010; 3(1)e5
[http://dx.doi.org/10.3402/ehtj.v3i0.7104] [PMID: 22460395]
[8]
Terlecki RP, Triest JA. A contemporary evaluation of the auditory hazard of extracorporeal shock wave lithotripsy. Urology 2007; 70(5): 898-9.
[http://dx.doi.org/10.1016/j.urology.2007.06.1151] [PMID: 18068444]
[9]
Tiselius HG. Epidemiology and medical management of stone disease. BJU Int 2003; 91(8): 758-67.
[http://dx.doi.org/10.1046/j.1464-410X.2003.04208.x] [PMID: 12709088]
[10]
Moe OW. Kidney stones: Pathophysiology and medical management. Lancet 2006; 367(9507): 333-44.
[http://dx.doi.org/10.1016/S0140-6736(06)68071-9] [PMID: 16443041]
[11]
Ahmed S, Hasan MM, Mahmood ZA. Antiurolithiatic plants in different countries and cultures. J Pharmacogn Phytochem 2016; 5(1): 102.
[PMID: 28375136]
[12]
Morris JB, Wang ML, Grusak MA, Tonnis B. Fatty acid, flavonol, and mineral composition variability among seven Macrotyloma uniflorum [Lam. Verdc. accessions. Agriculture 2013; 3(1): 157-69.
[http://dx.doi.org/10.3390/agriculture3010157]
[13]
Ahmed S, Hasan Mahmood Z A. Basic composition and caloric contents of Macrotyloma uniflorum [Lam.] Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., legume flours. PHARMANEST - An International Journal of Advances in Pharmaceutical Sciences 2015; 6(5): 2984-7.
[14]
Hiremath J, Sharan S, Vishwanath KS. Chemical composition and functional properties of some important genotypes of horsegram. Karnataka J Agric Sci 2001; 14(4): 943-6.
[15]
Ravindran R, Sundar SB. Nutritive value of horse gram [Dolichos biflorus] for egg-type chicks and growers. Tamilnadu J Veterinary & Animal Sciences 2009; 5(4): 125-31.
[16]
Bolbhat S, Dhumal K. Mineral constituents in seeds of horsegram mutants. Int J Adv Scientif Technic Res 2014; 4: 15-21.
[17]
Kadam SS, Salunkhe DK, Maga JA. Nutritional composition, processing, and utilization of horse gram and moth bean. Crit Rev Food Sci Nutr 1985; 22(1): 1-26.
[http://dx.doi.org/10.1080/10408398509527407] [PMID: 3899515]
[18]
Thenmozhi K, Manian S, Paulsamy S. Preliminary phytochemical screening from different Parts of Bauhinia tomentosa L. and Bauhinia malabarica. 2012; 11-7.
[19]
Chirinos R, Campos D, Costa N, Arbizu C, Pedreschi R, Larondelle Y. Phenolic profiles of Andean mashua [Tropaeolum tuberosum Ruيz & Pavَn] tubers: Identification by HPLC-DAD and evaluation of their antioxidant activity. Food Chem 2008; 106(3): 1285-98.
[http://dx.doi.org/10.1016/j.foodchem.2007.07.024]
[20]
Alonso-Amelot M, Oliveros-Bastidas A, Arellano E. Extraction efficiency of phenolics and tannins from some sun-exposed neotropical forbs and shrubs in a mountain habitat. Ciencia 2005; 13: 429-39.
[21]
Mahjoub F, Akhavan Rezayat K, Yousefi M, Mohebbi M, Salari R. Pistacia atlantica Desf. A review of its traditional uses, phytochemicals and pharmacology. J Med Life 2018; 11(3): 180-6.
[http://dx.doi.org/10.25122/jml-2017-0055] [PMID: 30364651]
[22]
Amz R. Alavi. Beirut: Daralehya -altars al-Arabi 1991; pp. 79-314.
[23]
Aghili Khorasani SMH. Makhzan-al-Advia. Tehran 2001.
[24]
Al Qurashi A. Al-Shamel Fi-Alsenaat Altebbiah. United Arab Emirates: Al-Majmaa-Alseghafi 1958.
[25]
Tonekaboni SM. The gift of the believer. Tehran: Tehran, Publication of the City 2007. Tohfat al-moomenin
[26]
Kumar DS, Prashanthi G, Avasarala H, Banji D. Antihypercholesterolemic effect of Macrotyloma uniflorum (Lam.) Verdc (Fabaceae) extract on high-fat diet-induced hypercholesterolemia in Sprague-Dawley rats. J Diet Suppl 2013; 10(2): 116-28.
[http://dx.doi.org/10.3109/19390211.2013.790334] [PMID: 23725525]
[27]
Gupta S, Sharma P, Ansari S. Antimicrobial activity of Dolichos biflorus seeds. Indian J Nat Prod 2005; 21: 20.
[28]
Kawsar S, Serajuddin M, Huq E, Nahar N, Ozeki Y. Biological investigation of Macrotyloma uniflorum Linn. extracts against some pathogens. J Biol Sci 2008; 8(6): 1051-6.
[http://dx.doi.org/10.3923/jbs.2008.1051.1056]
[29]
Philip A, Athul P, Charan A, Afeefa T. Anthelmintic activity of seeds of Macrotyloma uniflorum. Hygeia 2009; 1(1): 26-7.
[30]
Sengupta K, Mishra AT, Rao MK, Sarma KV, Krishnaraju AV, Trimurtulu G. Efficacy of an herbal formulation LI10903F containing Dolichos biflorus and Piper betle extracts on weight management. Lipids Health Dis 2012; 11(1): 176.
[http://dx.doi.org/10.1186/1476-511X-11-176] [PMID: 23270333]
[31]
Bhartiya A, Aditya J, Kant L. Nutritional and remedial potential of an underutilized food legume horsegram [Macrotyloma uniflorum]: A review. JAPS 2015; 25(4)
[32]
Bigoniya P, Bais S, Sirohi B. The effect of Macrotyloma uniflorum seed on bile lithogenicity against diet induced cholelithiasis on mice. Anc Sci Life 2014; 33(4): 242-51.
[http://dx.doi.org/10.4103/0257-7941.147433] [PMID: 25593405]
[33]
Panda V, Suresh S. Gastro-protective effects of the phenolic acids of Macrotyloma uniflorum [horse gram] on experimental gastric ulcer models in rats. Food Biosci 2015; 12: 34-46.
[http://dx.doi.org/10.1016/j.fbio.2015.07.004]
[34]
Fatima SA, Baig SG, Hasan MM, Ahmed S. Salma. Analgesic and anti-inflammatory activities of fixed oil of Macrotyloma uniflorum (Lam.) Verdc. in mice and rats. Pak J Pharm Sci 2018; 31(2): 581-5.
[PMID: 29618451]
[35]
Suralkar AA, Sanjay BK. Evaluation of antihistaminic activity of Dolichos biflorus. Int J Pharma Bio Sci 2013; 4(4): 346-P52.
[36]
Bijarnia RK, Kaur T, Singla SK, Tandon C. Non-surgical management therapies for kidney stones. J Pharm Educ Res 2010; 1(1): 21.
[37]
Chaitanya DAK, Kumar MS, Reddy A, Mukherjee A, Sumanth M, Ramesh A. Anti urolithiatic activity of Macrotyloma uniflorum seed extract on ethylene glycol induced urolithiasis in albino rats. J Innov Trends Pharm Sci 2010; 1: 216-26.
[38]
Garimella TS, Jolly CI, Narayanan S. In vitro studies on antilithiatic activity of seeds of Dolichos biflorus Linn. and rhizomes of Bergenia ligulata Wall. Phytother Res 2001; 15(4): 351-5.
[http://dx.doi.org/10.1002/ptr.833] [PMID: 11406861]
[39]
Nagal A, Singla RK. Herbal resources with antiurolithiatic effects: A review. Indo Glob J Pharm Sci 2013; 3(1): 6-14.
[40]
Ravishankar K, Priya P. Evaluation of diuretic effect of ethanolic seed extracts of Macrotyloma uniflorum and Cucumis melo in rats. Int J Pharm Bio Sci 2012; 3(3): 251-5.
[41]
Sma K, Mostafa G, Nahar N, Huq E. Chemical constitutions and hemolytic activity of Macrotyloma uniflorum Linn. Int J Nat Eng Sci 2009; 3(1): 69-72.
[42]
Saha S, Verma RJ. Efficacy study of Dolichos biflorus in the management of nephrotoxicity. Asian Pac J Trop Biomed 2012; 2(3): S1471-6.
[http://dx.doi.org/10.1016/S2221-1691(12)60440-7]
[43]
Kottaimuthu A, Sethupathy S, Manavalan R, Karar P. Antioxidant activity of flavonoids isolated from Dolichos biflorus Linn. In rabbits fed high-fat diet. Biosci Biotechnol Res Asia 2007; 4: 179.
[44]
Ravishankar K, Priya P. In-vitro anti-oxidant activity of.ethanolic seed extracts of M. uniflorum and Cucumismelo for therapeutic potential. Int J Res Pharm Chem 2012; 2(2): 442-5.
[45]
Marimuthu M, Krisnamoorthi K. In-vitro anti-oxidant potential of chlorofrom seed extract of under utilized/lesse dibble South Indian legumes. PHARMANEST- An International Journal of Advances in Pharmaceutical Sciences 2013; 4(4): 647-58.
[46]
Siddhuraju P, Manian S. The antioxidant activity and free radical-scavenging capacity of dietary phenolic extracts from horsegram seeds. Food Chem 2007; 105(3): 950-8.
[http://dx.doi.org/10.1016/j.foodchem.2007.04.040] [PMID: 26065757]
[47]
Parthsarthi Purwar B, Saxena Y. Effect of Dolichos biflorus on blood sugar and lipids in diabetic rats. Indian J Physiol Pharmacol 2013; 57(1): 63-71.
[PMID: 24020100]
[48]
Gupta LH, Badole SL, Bodhankar SL, Sabharwal SG. Anti-diabetic potential of αα-amylase inhibitor from the seeds of M. uniflorum in streptozotocin nicotinamide-induced diabetic mice. Pharm Biol 2010; 201149(2): 182-9.
[http://dx.doi.org/10.3109/13880209.2010.507633] [PMID: 21043992]
[49]
Muthu AK, Sethupathy S, Manavalan R, Karar P. Hypolipidemic effect of methanolic extract of Dolichos biflorus Linn. in high fat diet fed rats. Indian J Exp Biol 2005; 43(6): 522-5.
[PMID: 15991577]
[50]
Suralkar AA, Kasture SB. Anti-allergic and anti-anaphylactic activities of Dolichos biflorus. Int J Green Pharm 2013; 7(3): 196.
[51]
Curhan GC, Willett WC, Knight EL, Stampfer MJ. Dietary factors and the risk of incident kidney stones in younger women: Nurses’ Health Study II. Arch Intern Med 2004; 164(8): 885-91.
[http://dx.doi.org/10.1001/archinte.164.8.885] [PMID: 15111375]
[52]
Meschi T, Nouvenne A, Ticinesi A, et al. Dietary habits in women with recurrent idiopathic calcium nephrolithiasis. J Transl Med 2012; 10(1): 63.
[http://dx.doi.org/10.1186/1479-5876-10-63] [PMID: 22453026]
[53]
Fuselier HA, Moore K, Lindberg J, et al. Agglomeration inhibition reflected stone-forming activity during long-term potassium citrate therapy in calcium stone formers. Urology 1998; 52(6): 988-94.
[http://dx.doi.org/10.1016/S0090-4295(98)00361-6] [PMID: 9836542]
[54]
McNally MA, Pyzik PL, Rubenstein JE, Hamdy RF, Kossoff EH. Empiric use of potassium citrate reduces kidney-stone incidence with the ketogenic diet. Pediatrics 2009; 124(2): e300-4.
[http://dx.doi.org/10.1542/peds.2009-0217] [PMID: 19596731]
[55]
Danielson B. Drugs against kidney stones: Effects of magnesium and alkali. In: Schwille PO, Smith LH, Robertson WG, Vahlensieck W, Eds. Urolithiasis and Related Clinical Research. Boston, MA: Springer, 1985; pp. 525-32.
[56]
Wu J, Yang Z, Wei J, Zeng C, Wang Y. Association between serum magnesium and the prevalence of kidney stones: A cross-sectional study 2020; 195(1): 20-6.
[57]
Curhan GC, Willett WC, Speizer FE, Stampfer MJ. Intake of vitamins B6 and C and the risk of kidney stones in women. J Am Soc Nephrol 1999; 10(4): 840-5.
[http://dx.doi.org/10.1681/ASN.V104840] [PMID: 10203369]
[58]
Curhan GC, Willett WC, Rimm EB, Stampfer MJ. A prospective study of the intake of vitamins C and B6, and the risk of kidney stones in men. J Urol 1996; 155(6): 1847-51.
[http://dx.doi.org/10.1016/S0022-5347(01)66027-0] [PMID: 8618271]
[59]
Ferraro PM, Taylor EN, Gambaro G, Curhan GC. Vitamin B6 intake and the risk of incident kidney stones. Urolithiasis 2018; 46(3): 265-70.
[http://dx.doi.org/10.1007/s00240-017-0999-5] [PMID: 28674784]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy