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ISSN (Print): 2210-3155
ISSN (Online): 2210-3163

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Review Article

A Review of Phytoconstituents as Antibacterial Agents

Author(s): Gunjan Bisht, Ankit Kumar Singh, Adarsh Kumar and Pradeep Kumar*

Volume 13, Issue 5, 2023

Published on: 10 October, 2022

Article ID: e040822207273 Pages: 18

DOI: 10.2174/2210315512666220804111049

Price: $65

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Abstract

Background bacteria cause various infectious diseases and cause millions of deaths each year. Bacteria are broadly classified based on the phenotypic and genotypic systems. Bacteria cause resistance mainly by Plasmids, Inactivation of antibiotics, Target site modification, Preventing drug uptake, Efflux pumps, and Biofilm. Plants have been used for thousands of years for their medicinal properties to treat various diseases. Secondary metabolites like terpenes, alkaloids, phenolic compounds, tannins, quinones, steroids, polyketides, aromatics, and peptides are plant-derived compounds that possess antibacterial activity and decrease resistance by inhibition of biofilm formation, Efflux pump [EP] inhibitors, attenuating bacterial virulence, and Immunomodulation activity. Phytoconstituents synergism, combination therapy (Bio-enhancers), and herbal preparation benefit antibacterial potential and decrease resistance.

Keywords: Bacteria, Antibacterial, Secondary metabolites, Peptides, Alkaloids, Tannins

Graphical Abstract

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