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Infectious Disorders - Drug Targets

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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

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Case Report

Extensive Multifocal Emphysematous Osteomyelitis of Spine: A Rare Case and a Review of Literature

Author(s): Bhawna Sharma, Vikas Lakhanpal, Abeer Goyal, Ritu Shree, Shashank Raj, Priya Sreenivasan, Manisha Biswal, Pallab Ray and Archana Angrup*

Volume 23, Issue 1, 2023

Published on: 04 October, 2022

Article ID: e140622205976 Pages: 8

DOI: 10.2174/1871526522666220614163310

Price: $65

Abstract

Background: Emphysematous osteomyelitis (EO) is an extremely rare form of osteomyelitis which is complicated mainly by infection with gas-forming organisms. The common causative agents of this disease are mainly members of Enterobacteriaceae family, the most common are Escherichia coli and Klebsiella pneumoniae along with anaerobes. A total of 48 cases of EO have been reported in the literature till now globally and none have documented the isolation of Corynebacterium amycolatum.

Case Presentation: We report a rare case of emphysematous osteomyelitis of the spine and pelvis due to Escherichia coli along with the isolation of Corynebacterium amycolatum from the same pus samples on two consecutive occasions in a 50-year-old female with uncontrolled diabetes mellitus, who was successively treated with antibiotics and drainage of pus. We also did a brief review of the literature of all cases reported till now.

Conclusion: The role of Corynebacterium amycolatum in the etiology of emphysematous osteomyelitis needs to be evaluated further in future studies as we cannot completely ignore its isolation in two consecutive samples as a mere contaminant.

Keywords: Escherichia coli, Corynebacterium amycolatum, enterobacteriaceae, emphysematous, osteomyelitis, spine.

Graphical Abstract

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