Jugular Paraganglioma Presenting with a Tumor Thrombus Extending from Posterior Fossa to Right Atrium and Multiple Skeletal Metastases

Title:Jugular Paraganglioma Presenting with a Tumor Thrombus Extending from Posterior Fossa to Right Atrium and Multiple Skeletal Metastases

Volume: 18

Author(s): Umur Anil Pehlivan*, Kadir Oktay, Hasan Bilen Onan, Arbil Acikalin, Celalet Keser and Semra Paydas

Affiliation:

• Department of Radiology, Van Başkale State Hospital, Van, Turkey

Keywords: Malignant jugular paraganglioma, long-segment tumor thrombus, multiple skeletal metastases, case report, chemotherapy, tumors.

Abstract:

Introduction: Paragangliomas are tumors of neuroendocrine origin, may appear in different localizations, and are related to the autonomic nervous system. Paragangliomas are generally asymptomatic and may rarely appear with adrenergic symptoms, and clinical findings depend on the catecholamines they secrete. Extra-adrenal paragangliomas are mostly benign, like all paragangliomas. Malignancy criteria consist of local recurrence, metastasis after total resection, and presence of distant metastasis during primary diagnosis.

Case Presentation: This report presents the case of a 31-year-old man with jugular paraganglioma, multiple skeletal metastases, and a long-segment tumor thrombus. Imaging procedures showed a continuous tumor thrombus extending from the posterior fossa to the right atrium and metastases in C2, T1, T6, T8, L5, and right humerus. Histopathological assessment of the metastasis in C2 identified malignant paraganglioma. Curative surgery was not an option for this patient, hence combined chemotherapy was given.

Conclusion: In cases of malignant paraganglioma with multiple distant metastases, chemotherapy and radiotherapy are feasible treatment methods.

Cite this article as:

Pehlivan Anil Umur*, Oktay Kadir, Onan Bilen Hasan, Acikalin Arbil, Keser Celalet and Paydas Semra, Jugular Paraganglioma Presenting with a Tumor Thrombus Extending from Posterior Fossa to Right Atrium and Multiple Skeletal Metastases, Current Medical Imaging 2022; 18 (13) : e020622205567 . https://dx.doi.org/10.2174/1573405618666220602121607

DOI https://dx.doi.org/10.2174/1573405618666220602121607	Print ISSN 1573-4056
Publisher Name Bentham Science Publisher	Online ISSN 1875-6603