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Current Bioactive Compounds

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ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

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Mini-Review Article

Antimicrobial Activity of Bioactive Compounds Isolated from Plant Endophytes

Author(s): Sudesh Kumari, Prity Gulia, Namita Sharma, Sweety Dahiya, Pooja Choudhary and Anil Kumar Chhillar*

Volume 19, Issue 3, 2023

Published on: 03 October, 2022

Article ID: e240522205175 Pages: 9

DOI: 10.2174/1573407218666220524120648

Price: $65

Abstract

To combat the escalating antimicrobial resistance, we must constantly develop new medications. Recently, scientists more focused on endophytes to search for novel antimicrobial natural products. Endophytes are explored as 'bio-factories' of natural bioactive therapeutic compounds. These are microbes exhibited in plant living tissues without causing any harmful effect. Many therapeutic compounds isolated from endophytes are produced from biosynthetic pathways and belong to various structural groups like terpenoids, steroids, quinines, and phenols. Therapeutic compounds produced by endophytes exhibit different pharmacological properties. Fungal genera more commonly reside to plant tissue as compared to bacterial genera. The current review emphasizes comprehensive data on the antibacterial and antifungal activity and bio-therapeutic compounds produced by fungal and bacterial endophytes of some medicinal plants.

Keywords: Medicinal Plants, Endophytes, Natural products, Antibacterial, Antifungal, Therapeutic compounds

Graphical Abstract

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