Abstract
Alzheimer’s disease (AD) is a common cause of dementia; the hallmark includes neuronal death and synaptic loss leading to cognitive decline. Up to date, there have been a vast number of preclinical and clinical trials based on natural compounds that play a crucial role in the prevention of AD. Tinospora cordifolia (Tc) is a medicinal plant with numerous bioactive properties used in Indian medicine. The literature study will scrutinized based on the disease-modifying effects of Tinospora cordifolia. It benefits the neurobiological researcher in understanding and researching the naturally occurring compound in combating AD. Furthermore, recent nanotechnology trends, such as green synthesis nanoparticles, have more potential in biomedical fields. Following that, the review draws attention to the green synthesized nanoparticle of Tc, which has a wide range of applications.
Keywords: Tinospora cordifolia (Tc), pharmacological activity, antioxidant, alzheimer’s disease, green synthesis nanoparticle.
Graphical Abstract
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