What is the Role of Tranexamic Acid in the Management of Postpartum
Haemorrhage? State of Art and Perspectives

Filippo   Alberto   Ferrari; Simone   Garzon   Garz; Francesca      Cisotto; Stefano      Uccella; Massimo      Franchi
doi:10.2174/1573404818666220520152808
Abstract

Primary postpartum haemorrhage (PPH) complicates the postpartum up to 11% of deliveries with different incidences based on geographical regions and is the first cause of maternal deaths, accounting for 25% of cases. Tranexamic acid may play a role in the delicate postpartum balance in case of PPH, inhibiting the conversion of plasminogen to plasmin and reducing the degradation of fibrin. We analyze literature evidence and the possible role of tranexamic acid in clinical practice and future scenarios.
Keywords: Tranexamic acid, vaginal delivery, caesarean section, primary postpartum haemorrhage, obstetric care, uterine atony
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DOI https://dx.doi.org/10.2174/1573404818666220520152808	Print ISSN 1573-4048
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What is the Role of Tranexamic Acid in the Management of Postpartum Haemorrhage? State of Art and Perspectives

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