Biological Functions and Applications of Antimicrobial Peptides

Lei      Wang; Linkai      Qu; Sue      Lin; Qinsi      Yang; Xingxing      Zhang; Libo      Jin; Hao      Dong; Da      Sun
doi:10.2174/1389203723666220519155942
Abstract

Despite antimicrobial resistance, which is attributed to the misuse of broad-spectrum antibiotics, antibiotics can indiscriminately kill pathogenic and beneficial microorganisms. These events disrupt the delicate microbial balance in both humans and animals, leading to secondary infections and other negative effects. Antimicrobial peptides (AMPs) are functional natural biopolymers in plants and animals. Due to their excellent antimicrobial activities and absence of microbial resistance, AMPs have attracted enormous research attention. We reviewed the antibacterial, antifungal, antiviral, antiparasitic, as well as antitumor properties of AMPs and research progress on AMPs. In addition, we highlighted various recommendations and potential research areas for their progress and challenges in practical applications.
Keywords: Antimicrobial peptides, microbial resistance, antimicrobial activity, action mechanism, achievement transformation, clinical application.
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DOI https://dx.doi.org/10.2174/1389203723666220519155942	Print ISSN 1389-2037
Publisher Name Bentham Science Publisher	Online ISSN 1875-5550
Current Protein & Peptide Science

Biological Functions and Applications of Antimicrobial Peptides

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