Generic placeholder image

Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Clinical Characterizations and Radiological Findings of COVID-19: A 4 Case Report

Author(s): Zhenguo Qiao, Dong Liu, Fangfang Fu, Aihua Ye* and Chunhong Hu*

Volume 18, Issue 14, 2022

Published on: 10 June, 2022

Article ID: e040422203088 Pages: 4

DOI: 10.2174/1573405618666220404161324

Price: $65

Abstract

Background: Coronavirus disease 2019 (COVID-19, previously known as novel coronavirus [2019-nCoV]), first reported in China, has now been declared a global health emergency by World Health Organization. The clinical severity ranges from asymptomatic individuals to death. Here, we report clinical features and radiological changes of a cured family cluster infected with COVID-19.

Case Presentation: In this report, we enrolled a family of 4 members who were admitted to our hospital in January 2020. We performed a detailed analysis of each patient’s records. All patients underwent chest computed tomography (CT) examination with 120 kilovolts peak and 150 kilovolt-ampere. Realtime polymerase chain reaction (RT-PCR) examinations for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid were done using nasopharyngeal swabs.

Conclusion: In the family members infected with COVID-19 who were accompanied by other diseases or had low immunity, the pneumonia was prone to be aggravated.

Keywords: COVID-19, family members, diagnosis, treatment, CT, real-time polymerase chain reaction.

Graphical Abstract

[1]
Zhu N, Zhang D, Wang W, et al. China Novel Coronavirus Investigating and Research Team. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382(8): 727-33.
[http://dx.doi.org/10.1056/NEJMoa2001017] [PMID: 31978945]
[2]
Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. Lancet 2020; 395(10223): 514-23.
[http://dx.doi.org/10.1016/S0140-6736(20)30154-9] [PMID: 31986261]
[3]
Pan X, Chen D, Xia Y, et al. Asymptomatic cases in a family cluster with SARS-CoV-2 infection. Lancet Infect Dis 2020; 20(4): 410-1.
[http://dx.doi.org/10.1016/S1473-3099(20)30114-6] [PMID: 32087116]
[4]
Hu X, Chen J, Jiang X, et al. CT imaging of two cases of one family cluster 2019 novel coronavirus (2019-nCoV) pneumonia: Inconsistency between clinical symptoms amelioration and imaging sign progression. Quant Imaging Med Surg 2020; 10(2): 508-10.
[http://dx.doi.org/10.21037/qims.2020.02.10] [PMID: 32190575]
[5]
Müller NL, Ooi GC, Khong PL, Zhou LJ, Tsang KW, Nicolaou S. High-resolution CT findings of severe acute respiratory syndrome at presentation and after admission. AJR Am J Roentgenol 2004; 182(1): 39-44.
[http://dx.doi.org/10.2214/ajr.182.1.1820039] [PMID: 14684509]
[6]
Nicolaou S, Al-Nakshabandi NA, Müller NL. SARS: Imaging of severe acute respiratory syndrome. AJR Am J Roentgenol 2003; 180(5): 1247-9.
[http://dx.doi.org/10.2214/ajr.180.5.1801247] [PMID: 12704032]
[7]
Ooi GC, Khong PL, Müller NL, et al. Severe acute respiratory syndrome: Temporal lung changes at thin-section CT in 30 patients. Radiology 2004; 230(3): 836-44.
[http://dx.doi.org/10.1148/radiol.2303030853] [PMID: 14990845]
[8]
Das KM, Lee EY, Al Jawder SE, et al. Acute middle east respiratory syndrome coronavirus: Temporal lung changes observed on the chest radiographs of 55 patients. AJR Am J Roentgenol 2015; 205(3)W267-74
[http://dx.doi.org/10.2214/AJR.15.14445] [PMID: 26102309]
[9]
Das KM, Lee EY, Enani MA, et al. CT correlation with outcomes in 15 patients with acute Middle East respiratory syndrome coronavirus. AJR Am J Roentgenol 2015; 204(4): 736-42.
[http://dx.doi.org/10.2214/AJR.14.13671] [PMID: 25615627]
[10]
Ozdemir MA, Ozdemir GD, Guren O. Classification of COVID-19 electrocardiograms by using hexaxial feature mapping and deep learning. BMC Med Inform Decis Mak 2021; 21(1): 170.
[http://dx.doi.org/10.1186/s12911-021-01521-x] [PMID: 34034715]
[11]
Ho JC, Chan KN, Hu WH, et al. The effect of aging on nasal mucociliary clearance, beat frequency, and ultrastructure of respiratory cilia. Am J Respir Crit Care Med 2001; 163(4): 983-8.
[http://dx.doi.org/10.1164/ajrccm.163.4.9909121] [PMID: 11282777]
[12]
Kumar P, Erturk VS, Murillo-Arcila M, Banerjee R, Manickam A. A case study of 2019-nCOV cases in Argentina with the real data based on daily cases from March 03, 2020 to March 29, 2021 using classical and fractional derivatives. Adv Differ Equ 2021; 2021(1): 341.
[http://dx.doi.org/10.1186/s13662-021-03499-2] [PMID: 34306044]
[13]
Ulinici M, Covantev S, Wingfield-Digby J, Beloukas A, Mathioudakis AG, Corlateanu A. Screening, diagnostic and prognostic tests for COVID-19: A comprehensive review. Life (Basel) 2021; 11(6): 561.
[http://dx.doi.org/10.3390/life11060561] [PMID: 34198591]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy