Abstract
Background: Coronavirus disease 2019 (COVID-19, previously known as novel coronavirus [2019-nCoV]), first reported in China, has now been declared a global health emergency by World Health Organization. The clinical severity ranges from asymptomatic individuals to death. Here, we report clinical features and radiological changes of a cured family cluster infected with COVID-19.
Case Presentation: In this report, we enrolled a family of 4 members who were admitted to our hospital in January 2020. We performed a detailed analysis of each patient’s records. All patients underwent chest computed tomography (CT) examination with 120 kilovolts peak and 150 kilovolt-ampere. Realtime polymerase chain reaction (RT-PCR) examinations for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid were done using nasopharyngeal swabs.
Conclusion: In the family members infected with COVID-19 who were accompanied by other diseases or had low immunity, the pneumonia was prone to be aggravated.
Keywords: COVID-19, family members, diagnosis, treatment, CT, real-time polymerase chain reaction.
Graphical Abstract
[http://dx.doi.org/10.1056/NEJMoa2001017] [PMID: 31978945]
[http://dx.doi.org/10.1016/S0140-6736(20)30154-9] [PMID: 31986261]
[http://dx.doi.org/10.1016/S1473-3099(20)30114-6] [PMID: 32087116]
[http://dx.doi.org/10.21037/qims.2020.02.10] [PMID: 32190575]
[http://dx.doi.org/10.2214/ajr.182.1.1820039] [PMID: 14684509]
[http://dx.doi.org/10.2214/ajr.180.5.1801247] [PMID: 12704032]
[http://dx.doi.org/10.1148/radiol.2303030853] [PMID: 14990845]
[http://dx.doi.org/10.2214/AJR.15.14445] [PMID: 26102309]
[http://dx.doi.org/10.2214/AJR.14.13671] [PMID: 25615627]
[http://dx.doi.org/10.1186/s12911-021-01521-x] [PMID: 34034715]
[http://dx.doi.org/10.1164/ajrccm.163.4.9909121] [PMID: 11282777]
[http://dx.doi.org/10.1186/s13662-021-03499-2] [PMID: 34306044]
[http://dx.doi.org/10.3390/life11060561] [PMID: 34198591]