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Current Nutrition & Food Science

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ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

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Meta-Analysis

Does Nicotine from Passive Smoking and Foods Protect Against Parkinson’s Disease?

Author(s): Arezoo Fathalizadeh, Sarvin Sanaie, Mojgan Mirghafourvand, Anita Reyhanifard, Sama Rahnemayan, Ata Mahmoodpoor and Elnaz Faramarzi*

Volume 19, Issue 1, 2023

Published on: 14 June, 2022

Page: [74 - 82] Pages: 9

DOI: 10.2174/1573401318666220401112508

Price: $65

Abstract

Background: There is generally a strong link between smoking, more particularly, passive smoking, and the occurrence of various illnesses and health-related disorders. Also, there is a globally recognized epidemiological link between smoking and Parkinson’s disease (PD). However, the current data on passive smoking are contradictory. Thus, this paper extracted the inconsistent existing studies to systematically shed light on the slightly ambiguous protective properties of dietary nicotine and passive smoking as influential factors against PD.

Methods: This systematic review was registered in PROSPERO (CRD042020160707). Two independent researchers searched through the following databases: PubMed, Cochrane Library, Scopus, Ovid, Embase, Google Scholar, and ProQuest to find relevant dissertations and theses. This study involved the data of papers published until 30th September, 2020. The Newcastle- Ottawa scale (NOS) was used for case-control and cohort studies for quality assessment. The study extracted cases without a history of smoking and the number of patients with PD in the workspace, home, and lifetime and organized them based on each research. The study implemented Q-statistic to investigate the selected papers based on statistical heterogeneity.

Result: In total, four cohorts and five case-control papers were included. Our findings indicated that lifetime exposure to smoking had a protective effect against PD risks (OR: 0.84; 95% CI: 0.70-0.99; p =0.04). However, the settings, workspace, home exposure, and PD risk did not display to have any considerable relationship. It should be noted that the studies on the relationship between dietary nicotine and PD risks have revealed the protective effect of nicotine-rich foods, like potatoes, tomatoes, and peppers, on PD risks.

Conclusion: In light of the observational studies covered in this paper, its findings should receive an organized interpretation while identifying the relevant mechanisms of this association.

Keywords: Parkinson's disease, passive smoking, home exposure, work exposure, lifetime exposure, systematic review.

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[1]
Wirdefeldt K, Adami HO, Cole P, Trichopoulos D, Mandel J. Epidemiology and etiology of Parkinson’s disease: A review of the evidence. Eur J Epidemiol 2011; 26 (Suppl. 1): S1-S58.
[http://dx.doi.org/10.1007/s10654-011-9581-6] [PMID: 21626386]
[2]
Parkinson J. An essay on the shaking palsy. J Neuropsychiatry Clin Neurosci 2002; 14: 223-36.
[3]
Braak H, Ghebremedhin E, Rüb U, Bratzke H, Del Tredici K. Stages in the development of Parkinson’s disease-related pathology. Cell Tissue Res 2004; 318(1): 121-34.
[http://dx.doi.org/10.1007/s00441-004-0956-9] [PMID: 15338272]
[4]
Scott WK, Zhang F, Stajich JM, Scott BL, Stacy MA, Vance JM. Family-based case-control study of cigarette smoking and Parkinson disease. Neurology 2005; 64(3): 442-7.
[http://dx.doi.org/10.1212/01.WNL.0000150905.93241.B2] [PMID: 15699372]
[5]
Tanner CM, Ottman R, Goldman SM, et al. Parkinson disease in twins: An etiologic study. JAMA 1999; 281(4): 341-6.
[http://dx.doi.org/10.1001/jama.281.4.341] [PMID: 9929087]
[6]
Van Maele-Fabry G, Hoet P, Vilain F, Lison D. Occupational exposure to pesticides and Parkinson’s disease: A systematic review and meta-analysis of cohort studies. Environ Int 2012; 46: 30-43.
[http://dx.doi.org/10.1016/j.envint.2012.05.004] [PMID: 22698719]
[7]
Breckenridge CB, Berry C, Chang ET, Sielken RL Jr, Mandel JS. Association between Parkinson’s disease and cigarette smoking, rural living, well-water consumption, farming and pesticide use: Systematic review and meta-analysis. PLoS One 2016; 11(4)e0151841
[http://dx.doi.org/10.1371/journal.pone.0151841] [PMID: 27055126]
[8]
Mathers C, Stevens G, d’Espaignet E, Wolfenden L. WHO global report: Mortality attributable to tobacco. World Health Organization 2012.
[9]
Checkoway H, Powers K, Smith-Weller T, Franklin GM, Longstreth WT Jr, Swanson PD. Parkinson’s disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake. Am J Epidemiol 2002; 155(8): 732-8.
[http://dx.doi.org/10.1093/aje/155.8.732] [PMID: 11943691]
[10]
Chen H, Huang X, Guo X, et al. Smoking duration, intensity, and risk of Parkinson disease. Neurology 2010; 74(11): 878-84.
[http://dx.doi.org/10.1212/WNL.0b013e3181d55f38] [PMID: 20220126]
[11]
Hernán MA, Takkouche B, Caamaño-Isorna F, Gestal-Otero JJ. A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson’s disease. Ann Neurol 2002; 52(3): 276-84.
[http://dx.doi.org/10.1002/ana.10277] [PMID: 12205639]
[12]
Li X, Li W, Liu G, Shen X, Tang Y. Association between cigarette smoking and Parkinson’s disease: A meta-analysis. Arch Gerontol Geriatr 2015; 61(3): 510-6.
[http://dx.doi.org/10.1016/j.archger.2015.08.004] [PMID: 26272284]
[13]
Ritz B, Ascherio A, Checkoway H, et al. Pooled analysis of tobacco use and risk of Parkinson disease. Arch Neurol 2007; 64(7): 990-7.
[http://dx.doi.org/10.1001/archneur.64.7.990] [PMID: 17620489]
[14]
Fowler JS, Wang GJ, Volkow ND, et al. Smoking a single cigarette does not produce a measurable reduction in brain MAO B in non-smokers. Nicotine Tob Res 1999; 1(4): 325-9.
[http://dx.doi.org/10.1080/14622299050011451] [PMID: 11072429]
[15]
Janson AM, Fuxe K, Goldstein M. Differential effects of acute and chronic nicotine treatment on MPTP-(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced degeneration of nigrostriatal dopamine neurons in the black mouse. Clin Investig 1992; 70(3-4): 232-8.
[http://dx.doi.org/10.1007/BF00184656] [PMID: 1521037]
[16]
McKenney J, Valeri CR, Mohandas N, Fortier N, Giorgio A, Snyder LM. Decreased in vivo survival of hydrogen peroxide-damaged baboon red blood cells. Blood 1990; 76(1): 206-11.
[http://dx.doi.org/10.1182/blood.V76.1.206.206] [PMID: 2364171]
[17]
Rapier C, Lunt GG, Wonnacott S. Nicotinic modulation of [3H]dopamine release from striatal synaptosomes: Pharmacological characterisation. J Neurochem 1990; 54(3): 937-45.
[http://dx.doi.org/10.1111/j.1471-4159.1990.tb02341.x] [PMID: 2303820]
[18]
Grady S, Marks MJ, Wonnacott S, Collins AC. Characterization of nicotinic receptor-mediated [3H]dopamine release from synaptosomes prepared from mouse striatum. J Neurochem 1992; 59(3): 848-56.
[http://dx.doi.org/10.1111/j.1471-4159.1992.tb08322.x] [PMID: 1494911]
[19]
Mellick GD, Gartner CE, Silburn PA, Battistutta D. Passive smoking and Parkinson disease. Neurology 2006; 67(1): 179-80.
[http://dx.doi.org/10.1212/01.wnl.0000223618.53129.56] [PMID: 16832110]
[20]
Gatto NM, Deapen D, Bordelon Y, Marshall S, Bernstein L, Ritz B. Passive smoking and Parkinson’s disease in California Teachers. Parkinsonism Relat Disord 2017; 45: 44-9.
[http://dx.doi.org/10.1016/j.parkreldis.2017.10.001] [PMID: 29033298]
[21]
Siegmund B, Leitner E, Pfannhauser W. Determination of the nicotine content of various edible nightshades (Solanaceae) and their products and estimation of the associated dietary nicotine intake. J Agric Food Chem 1999; 47(8): 3113-20.
[http://dx.doi.org/10.1021/jf990089w] [PMID: 10552617]
[22]
Brody AL, Mandelkern MA, London ED, et al. Cigarette smoking saturates brain α 4 β 2 nicotinic acetylcholine receptors. Arch Gen Psychiatry 2006; 63(8): 907-15.
[http://dx.doi.org/10.1001/archpsyc.63.8.907] [PMID: 16894067]
[23]
Han C, Lu Y, Cheng H, Wang C, Chan P. The impact of long-term exposure to ambient air pollution and second-hand smoke on the onset of Parkinson disease: A review and meta-analysis. Public Health 2020; 179: 100-10.
[http://dx.doi.org/10.1016/j.puhe.2019.09.020] [PMID: 31770719]
[24]
Cochran WG. The combination of estimates from different experiments. Biometric 1954; 10: 101-29.
[http://dx.doi.org/10.2307/3001666]
[25]
Searles Nielsen S, Gallagher LG, Lundin JI, et al. Environmental tobacco smoke and Parkinson’s disease. Mov Disord 2012; 27(2): 293-6.
[http://dx.doi.org/10.1002/mds.24012] [PMID: 22095755]
[26]
Tanaka K, Miyake Y, Fukushima W, et al. Active and passive smoking and risk of Parkinson’s disease. Acta Neurol Scand 2010; 122(6): 377-82.
[http://dx.doi.org/10.1111/j.1600-0404.2010.01327.x] [PMID: 20175761]
[27]
O’Reilly ÉJ, Chen H, Gardener H, Gao X, Schwarzschild MA, Ascherio A. Smoking and Parkinson’s disease: Using parental smoking as a proxy to explore causality. Am J Epidemiol 2009; 169(6): 678-82.
[http://dx.doi.org/10.1093/aje/kwn388] [PMID: 19131566]
[28]
Gallo V, Vineis P, Cancellieri M, et al. Exploring causality of the association between smoking and Parkinson’s disease. Int J Epidemiol 2019; 48(3): 912-25.
[PMID: 30462234]
[29]
Nielsen SS, Franklin GM, Longstreth WT, Swanson PD, Checkoway H. Nicotine from edible Solanaceae and risk of Parkinson disease. Ann Neurol 2013; 74(3): 472-7.
[http://dx.doi.org/10.1002/ana.23884] [PMID: 23661325]
[30]
Ma C, Molsberry S, Li Y, Schwarzschild M, Ascherio A, Gao X. Dietary nicotine intake and risk of Parkinson disease: A prospective study. Am J Clin Nutr 2020; 112(4): 1080-7.
[http://dx.doi.org/10.1093/ajcn/nqaa186] [PMID: 32725131]
[31]
Fall PA, Fredrikson M, Axelson O, Granérus AK. Nutritional and occupational factors influencing the risk of Parkinson’s disease: A case-control study in southeastern Sweden. Mov Disord 1999; 14(1): 28-37.
[http://dx.doi.org/10.1002/1531-8257(199901)14:1<28:AID-MDS1007>3.0.CO;2-O] [PMID: 9918341]
[32]
Hellenbrand W, Boeing H, Robra B-P, et al. Diet and Parkinson’s disease. II: A possible role for the past intake of specific nutrients. Results from a self-administered food-frequency questionnaire in a case-control study. Neurology 1996; 47(3): 644-50.
[http://dx.doi.org/10.1212/WNL.47.3.644] [PMID: 8797457]
[33]
Gao X, Chen H, Fung TT, et al. Prospective study of dietary pattern and risk of Parkinson disease. Am J Clin Nutr 2007; 86(5): 1486-94.
[http://dx.doi.org/10.1093/ajcn/86.5.1486] [PMID: 17991663]
[34]
Alcalay RN, Gu Y, Mejia-Santana H, Cote L, Marder KS, Scarmeas N. The association between Mediterranean diet adherence and Parkinson’s disease. Mov Disord 2012; 27(6): 771-4.
[http://dx.doi.org/10.1002/mds.24918] [PMID: 22314772]
[35]
Scheperjans F, Pekkonen E, Kaakkola S, Auvinen P. Linking smoking, coffee, urate, and Parkinson’s disease - A role for gut microbiota? J Parkinsons Dis 2015; 5(2): 255-62.
[http://dx.doi.org/10.3233/JPD-150557] [PMID: 25882059]
[36]
Quik M. Smoking, nicotine and Parkinson’s disease. Trends Neurosci 2004; 27(9): 561-8.
[http://dx.doi.org/10.1016/j.tins.2004.06.008] [PMID: 15331239]
[37]
Morens DM, Grandinetti A, Reed D, White LR, Ross GW. Cigarette smoking and protection from Parkinson’s disease: False association or etiologic clue? Neurology 1995; 45(6): 1041-51.
[http://dx.doi.org/10.1212/WNL.45.6.1041] [PMID: 7783862]
[38]
Tanner CM, Goldman SM, Aston DA, et al. Smoking and Parkinson’s disease in twins. Neurology 2002; 58(4): 581-8.
[http://dx.doi.org/10.1212/WNL.58.4.581] [PMID: 11865136]
[39]
Youdim MB, Fridkin M, Zheng H. Novel bifunctional drugs targeting monoamine oxidase inhibition and iron chelation as an approach to neuroprotection in Parkinson’s disease and other neurodegenerative diseases. J Neural Transm (Vienna) 2004; 111(10-11): 1455-71.
[http://dx.doi.org/10.1007/s00702-004-0143-x] [PMID: 15480846]
[40]
Linert W, Bridge MH, Huber M, Bjugstad KB, Grossman S, Arendash GW. In vitro and in vivo studies investigating possible antioxidant actions of nicotine: Relevance to Parkinson’s and Alzheimer’s diseases. Biochim Biophys Acta 1999; 1454(2): 143-52.
[http://dx.doi.org/10.1016/S0925-4439(99)00029-0] [PMID: 10381559]
[41]
Derkinderen P, Shannon KM, Brundin P. Gut feelings about smoking and coffee in Parkinson’s disease. Mov Disord 2014; 29(8): 976-9.
[http://dx.doi.org/10.1002/mds.25882] [PMID: 24753353]
[42]
Wang H, Zhao J-X, Hu N, Ren J, Du M, Zhu M-J. Side-stream smoking reduces intestinal inflammation and increases expression of tight junction proteins. World J Gastroenterol 2012; 18(18): 2180-7.
[http://dx.doi.org/10.3748/wjg.v18.i18.2180] [PMID: 22611310]

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