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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Review Article

Versatile Approach for the Synthesis of Furo-coumarin Derivatives

Author(s): Nidhi Singh, Krishna Rajotiya, Nikita Lamba, H.L. Singh, K.L. Ameta and Shivendra Singh*

Volume 26, Issue 3, 2022

Published on: 15 February, 2022

Page: [324 - 341] Pages: 18

DOI: 10.2174/1385272826666220126155703

Price: $65

Abstract

Owing to useful physio-chemical properties of furo-coumarin derivatives, their synthetic and mechanistic investigation has been reported here. We have demonstrated a range of synthetic approaches to access furan-fused coumarin derivatives. Many metalmediated, base, and acid-catalyzed approaches have been revealed for the formation of this coumarin-based fused heterocycles of biological importance. In addition to this, microwaveassisted synthetic routes have also been revealed. The last and most useful approach for the synthesis of these heterocycles includes the use of purely solvent as a reaction media for synthesizing these interesting classes of heterocycles.

Keywords: Furocoumarin, coumarin, furan, heterocycles, synthesis, natural products.

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