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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Editorial

Diarylurea: A Privileged Scaffold in Drug Discovery and Therapeutic Development

Author(s): Alessia Catalano*

Volume 29, Issue 25, 2022

Published on: 03 February, 2022

Page: [4302 - 4306] Pages: 5

DOI: 10.2174/0929867329666220111121251

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Catalano, A.; Iacopetta, D.; Sinicropi, M.S.; Franchini, C. Diarylureas as antitumor agents. Appl. Sci. (Basel), 2021, 11, 374.
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Catalano, A.; Iacopetta, D.; Pellegrino, M.; Aquaro, S.; Franchini, C.; Sinicropi, M.S. Diarylureas: Repositioning from antitumor to antimicrobials or multi-target agents against new pandemics. Antibiotics (Basel), 2021, 10(1), 92.
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Iacopetta, D.; Catalano, A.; Ceramella, J.; Saturnino, C.; Salvagno, L.; Ielo, I.; Drommi, D.; Scali, E.; Plutino, M.R.; Rosace, G.; Sinicropi, M.S. The different facets of triclocarban: A review. Molecules, 2021, 26(9), 2811.
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Pozzi, C.; Ferrari, S.; Cortesi, D.; Luciani, R.; Stroud, R.M.; Catalano, A.; Costi, M.P.; Mangani, S. The structure of Enterococcus fae-calis thymidylate synthase provides clues about folate bacterial metabolism. Acta Crystallogr. D Biol. Crystallogr., 2012, 68(Pt 9), 1232-1241.
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Catalano, A.; Iacopetta, D.; Rosato, A.; Salvagno, L.; Ceramella, J.; Longo, F.; Sinicropi, M.S.; Franchini, C. Searching for small mole-cules as antibacterials: Non-cytotoxic diarylureas analogues of triclocarban. Antibiotics (Basel), 2021, 10(2), 204.
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Catalano, A.; Rosato, A.; Salvagno, L.; Iacopetta, D.; Ceramella, J.; Fracchiolla, G.; Sinicropi, M.S.; Franchini, C. Benzothiazole-containing analogues of triclocarban with potent antibacterial activity. Antibiotics (Basel), 2021, 10(7), 803.
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Patterson, J.R.; Graves, A.P.; Stoy, P. Identification of diarylurea inhibitors of the cardiac-specific kinase TNNI3K by designing selec-tivity against VEGFR2, p38α and B-Raf. J. Med. Chem., 2021, 64(21), 15651-15670.
[http://dx.doi.org/10.1021/acs.jmedchem.1c00700]
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Catalano, A. COVID-19: Could irisin become the handyman myokine of the 21st century? Coronaviruses, 2020, 1, 32-41.
[http://dx.doi.org/10.2174/2666796701999200617154655]

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