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Current Stem Cell Research & Therapy

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ISSN (Print): 1574-888X
ISSN (Online): 2212-3946

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Mini-Review Article

Gli1+ Mesenchymal Stem Cells in Bone and Teeth

Author(s): Yange Wu, Xueman Zhou, Wenxiu Yuan, Jiaqi Liu, Wenke Yang, Yufan Zhu, Chengxinyue Ye, Xin Xiong, Qinlanhui Zhang, Jin Liu and Jun Wang*

Volume 17, Issue 6, 2022

Published on: 18 February, 2022

Page: [494 - 502] Pages: 9

DOI: 10.2174/1574888X17666220107102911

Price: $65

Abstract

Mesenchymal stem cells (MSCs) are remarkable and noteworthy. Identification of markers for MSCs enables the study of their niche in vivo. It has been identified that glioma-associated oncogene 1 positive (Gli1+) cells are mesenchymal stem cells supporting homeostasis and injury repair, especially in the skeletal system and teeth. This review outlines the role of Gli1+ cells as MSC subpopulation in both bones and teeth, suggesting the prospects of Gli1 an + cells in stem cell- based tissue engineering.

Keywords: Gli1, injury repair, mesenchymal stem cells, neurovascular bundle, suture, teeth.

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