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Current Cardiology Reviews

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ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

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An Update on New Cholesterol Inhibitor: Bempedoic Acid

Author(s): Mayank Kulshreshtha*

Volume 18, Issue 2, 2022

Published on: 13 January, 2022

Article ID: e141221198875 Pages: 4

DOI: 10.2174/1573403X17666211214111658

Abstract

An increase in the level of cholesterol day by day is easily seen in most people just because of poor life style, food with high cholesterol, lack of physical work, etc. There are lots of molecules available, which lower down the cholesterol level. In this field a new molecule has been introduced that is bimpedoic acid. Researches indicate that bempedoic acid has the same mechanism of action as statins, which means that it also inhibits the HMG-CoA reductase enzyme. This article is my best collection of published scientific data on bempedoic acid till now. It also includes the chemistry, pharmacodynamic and pharmacokinetic parameters of the mentioned new molecule.

Keywords: Cholesterol, bempedoic acid, HMG-CoA reductase enzyme, lipoproteins, gastrointestinal, hypoglycemic activity.

Graphical Abstract

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