Abstract
Guar gum (GG) is a natural heteropolysaccharide. Due to its non-toxic, eco-friendly, and biodegradable nature, GG has found wide applications in many areas, in particular food, paper, textile, petroleum, and pharmaceutical industries. Therefore, GG is often called “Black Gold” as well. Due to the presence of hydroxyl groups, GG can be modified by various methods. The physical and biological properties of GG can be modulated by chemical modifications. In this manuscript, various methods for the chemical modifications of GG have been discussed according to the type of modifications. Mechanistic insights have also been provided whenever possible. In addition, potential applications of new GG derivatives have also been briefly mentioned.
Keywords: Guar gum, galactomanan, natural product, polymer, polysaccharide, chemical modification, progress.
Graphical Abstract
[http://dx.doi.org/10.1146/annurev.bi.40.070171.000333] [PMID: 4256333]
[http://dx.doi.org/10.1007/BF02858718]
[http://dx.doi.org/10.1177/2158244017736094]
[http://dx.doi.org/10.1007/BF02862261]
[http://dx.doi.org/10.1016/B978-0-12-811449-0.00012-8]
[http://dx.doi.org/10.1007/s12892-009-0106-8]
[http://dx.doi.org/10.1016/j.ijbiomac.2013.05.017] [PMID: 23707734]
[http://dx.doi.org/10.4172/0974-8369.1000224]
[http://dx.doi.org/10.1002/jsfa.2308]
[http://dx.doi.org/10.1021/jf8039236]
[http://dx.doi.org/10.1007/s13197-011-0522-x] [PMID: 24587515]
[http://dx.doi.org/10.1016/0378-3774(93)90042-9]
[http://dx.doi.org/10.1016/j.ijbiomac.2011.04.022] [PMID: 21596058]
(b)Takahashi, T.; Yokawa, T.; Ishihara, N.; Okubo, T.; Chu, D.C.; Nishigaki, E.; Kawada, Y.; Kato, M.; Raj Juneja, L. Hydrolyzed guar gum decreases postprandial blood glucose and glucose absorption in the rat small intestine. Nutr. Res., 2009, 29(6), 419-425.
[http://dx.doi.org/10.1016/j.nutres.2009.05.013] [PMID: 19628109]
[http://dx.doi.org/10.3390/cosmetics6010013]
[http://dx.doi.org/10.1007/BF02858756]
[http://dx.doi.org/10.1016/S0065-2318(08)60339-X] [PMID: 782186]
[http://dx.doi.org/10.1007/978-3-642-36566-9_5]
[http://dx.doi.org/10.1016/j.carbpol.2004.08.013]
[http://dx.doi.org/10.1007/s40097-015-0172-z]
[http://dx.doi.org/10.1016/j.carbpol.2005.07.014]
[http://dx.doi.org/10.1002/app.29338]
(b)Kundu, S.; Das, A.; Basu, A.; Ghosh, D.; Datta, P.; Mukherjee, A. Carboxymethyl guar gum synthesis in homogeneous phase and macroporous 3D scaffolds design for tissue engineering. Carbohydr. Polym., 2018, 191, 71-78.
[http://dx.doi.org/10.1002/app.34173]]
[http://dx.doi.org/10.5138/ijdd.2010.0975.0215.02035]
(b)Gong, H.; Liu, M.; Chen, J.; Han, F.; Gao, C.; Zhang, B. Synthesis and characterization of carboxymethyl guar gum and rheological properties of its solutions. Carbohydr. Polym., 2012, 88, 1015-1022.
[http://dx.doi.org/10.1016/j.carbpol.2012.01.057]
[http://dx.doi.org/10.1002/star.200600594]
[http://dx.doi.org/10.1016/0141-8130(87)90001-8]
[http://dx.doi.org/10.1016/0144-8617(91)90006-X]
[http://dx.doi.org/10.1016/j.carbpol.2007.09.030]
[http://dx.doi.org/10.1016/j.carbpol.2007.09.030]
[http://dx.doi.org/10.1007/s11274-012-1027-0] [PMID: 22806052]
(b)Boonstar, D.J.; Bakker, A. Guar Gum derivatives and process for preparation. US Patent 3,912,713A, 1973.
[http://dx.doi.org/10.1016/j.carbpol.2010.01.044]
[http://dx.doi.org/10.1007/BF02710545]
[http://dx.doi.org/10.1016/j.carbpol.2012.06.032] [PMID: 22840030]
[http://dx.doi.org/10.1016/j.carbpol.2010.06.002]
[http://dx.doi.org/10.1080/01694243.2017.1306912]
(b)Gece, G. Drugs: A review of promising novel corrosion inhibitors. Corros. Sci., 2011, 53, 3873-3898.
[http://dx.doi.org/10.1016/j.corsci.2011.08.006]
[http://dx.doi.org/10.1016/j.matlet.2007.04.079]
[http://dx.doi.org/10.2174/1876503300902010175]
[http://dx.doi.org/10.1016/j.corsci.2012.12.020]
[http://dx.doi.org/10.1108/00368791111140431]
[http://dx.doi.org/10.1016/j.electacta.2005.02.116]
[http://dx.doi.org/10.1016/j.corsci.2012.11.042]
[http://dx.doi.org/10.1016/j.corsci.2012.04.002]
[http://dx.doi.org/10.1016/j.corsci.2013.12.018]
[http://dx.doi.org/10.1002/app.31559]
[http://dx.doi.org/10.1016/j.corsci.2012.02.009]
[http://dx.doi.org/10.1016/j.electacta.2009.11.011]
[http://dx.doi.org/10.1039/c3ra46549g]
[http://dx.doi.org/10.1002/app.1988.070350504]
[http://dx.doi.org/10.1016/j.corsci.2014.07.039]
[http://dx.doi.org/10.1016/j.carbpol.2008.10.014]
[http://dx.doi.org/10.1016/S0014-3057(01)00035-0]
[http://dx.doi.org/10.1016/j.carbpol.2004.04.010]
[http://dx.doi.org/10.1016/j.ijbiomac.2010.05.004] [PMID: 20471416]
(b)Mishra, S.; Sen, G. Microwave initiated synthesis of polymethylmethacrylate grafted guar (GG-g-PMMA), characterizations and applications. Int. J. Biol. Macromol., 2011, 48(4), 688-694.
[http://dx.doi.org/10.1016/j.ijbiomac.2011.02.013] [PMID: 21356236]
(c)Singh, A.; Liu, M.; Ituen, E.; Lin, Y. Anti-corrosive properties of an effective guar gum grafted 2-acrylamido-2 methylpropanesulfonic acid (GG-AMPS) coating on copper in a 3.5% NaCl solution. Coatings, 2020, 10(3), 241.
[http://dx.doi.org/10.3390/coatings10030241]
(d)Mitra, M.; Mahapatra, M.; Dutta, A.; Deb, M.; Dutta, S.; Chattopadhyay, P.K.; Roy, S.; Banerjee, S.; Sil, P.C.; Singha, N.R. Fluorescent guar gum-g-terpolymer via in situ acrylamido-acid fluorophore-monomer in cell imaging, Pb(II) sensor, and security ink. ACS Appl. Bio Mater., 2020, 3(4), 1995-2006.
[http://dx.doi.org/10.1021/acsabm.9b01146]
[http://dx.doi.org/10.1134/S0003683806030185]
[http://dx.doi.org/10.1016/j.ijbiomac.2008.12.006] [PMID: 19135473]
(b)Wang, X.; Wang, J.; Zhang, J.; Zhao, B.; Yao, J.; Wang, Y. Structure-antioxidant relationships of sulfated galactomannan from guar gum. Int. J. Biol. Macromol., 2010, 46(1), 59-66.
[http://dx.doi.org/10.1016/j.ijbiomac.2009.10.004] [PMID: 19836415]
(c)Wang, J.; Zhao, B.; Wang, X.; Yao, J.; Zhang, J. Structure and antioxidant activities of sulfated guar gum: homogeneous reaction using DMAP/DCC catalyst. Int. J. Biol. Macromol., 2012, 50(5), 1201-1206.
[http://dx.doi.org/10.1016/j.ijbiomac.2012.03.009] [PMID: 22484325]
[http://dx.doi.org/10.1021/bm010067u] [PMID: 11710057]
[http://dx.doi.org/10.1016/j.ijbiomac.2013.10.005] [PMID: 24120962]
[http://dx.doi.org/10.1016/j.cbi.2006.03.010] [PMID: 16756967]
[http://dx.doi.org/10.4314/wsa.v37i3.68480]
(b)Singh, A.V.; Gupta, S.; Gupta, S.C. Synthesis of a guaran-sulphonic acid cation-exchanger and its application in metal ion removal from underground mine water of the Rajpura Dariba Mines, Udaipur, India. Desalination, 1996, 104(3), 235-238.
[http://dx.doi.org/10.1016/0011-9164(96)00046-X]
[http://dx.doi.org/10.1016/j.jtice.2012.08.001]
[http://dx.doi.org/10.1039/CT9130301735]
[http://dx.doi.org/10.1039/CT9150700008]
[http://dx.doi.org/10.1016/S0040-4039(03)01871-9]
[http://dx.doi.org/10.1016/j.polymer.2005.10.083]
[http://dx.doi.org/10.1038/s41598-019-50991-7] [PMID: 31601861]
(b)Chen, F.; Wang, X.; Yang, R. Synthesis and Characterization of hydrophobic modification guar gum. Adv. Mat. Res., 2014, 952121-124.www.scientific.net/AMR.952.121
[http://dx.doi.org/10.4028/www.scientific.net/AMR.952.121]
[http://dx.doi.org/10.1002/app.32732]
[http://dx.doi.org/10.1016/j.carbpol.2013.07.041] [PMID: 24053847]
(b)Micard, V.; Belamri, R.; Morel, M.; Guilbert, S. Properties of chemically and physically treated wheat gluten films. J. Agric. Food Chem., 2000, 48(7), 2948-2953.
[http://dx.doi.org/10.1021/jf0001785] [PMID: 10898649]
(c)Rhim, J.W.; Hong, S.I.; Park, H.M.; Ng, P.K. Preparation and characterization of chitosan-based nanocomposite films with antimicrobial activity. J. Agric. Food Chem., 2006, 54(16), 5814-5822.
[http://dx.doi.org/10.1021/jf060658h] [PMID: 16881682]
[http://dx.doi.org/10.1016/0040-6031(88)85360-7]
[http://dx.doi.org/10.1002/app.30600]
[http://dx.doi.org/10.1016/j.carbpol.2011.07.003]
[http://dx.doi.org/10.1016/j.ijbiomac.2012.02.030] [PMID: 22402247]
[http://dx.doi.org/10.1016/j.matpr.2017.10.154]
[http://dx.doi.org/10.1016/j.biortech.2012.01.147] [PMID: 22357294]
[http://dx.doi.org/10.1016/j.carres.2020.107983] [PMID: 32229325]
[http://dx.doi.org/10.15373/22778179/MARCH2014/9]
[http://dx.doi.org/10.1021/ma101215d]
[http://dx.doi.org/10.1002/pen.23294]
[http://dx.doi.org/10.1039/C5RA23447F]
[http://dx.doi.org/10.1177/0885328218799551] [PMID: 30208770]
[http://dx.doi.org/10.1166/jbn.2013.1474] [PMID: 23627072]
[http://dx.doi.org/10.1016/j.ijbiomac.2017.01.062] [PMID: 28093331]
[http://dx.doi.org/10.1155/2016/6482461]
[http://dx.doi.org/10.1016/j.carbpol.2017.03.086] [PMID: 28457450]
[http://dx.doi.org/10.1021/acs.jafc.8b05130] [PMID: 30571099]
[http://dx.doi.org/10.1155/2019/7232715]
[http://dx.doi.org/10.1039/C7RA11687J]
[http://dx.doi.org/10.1016/j.apcata.2020.117529]
[http://dx.doi.org/10.1016/j.carbpol.2016.05.010] [PMID: 27312620]
[http://dx.doi.org/10.1016/j.ijbiomac.2019.04.042] [PMID: 30974140]
[http://dx.doi.org/10.1016/j.ijbiomac.2013.09.047]
[http://dx.doi.org/10.1016/j.carbpol.2014.08.045] [PMID: 25263907]
[http://dx.doi.org/10.1016/j.carbpol.2019.115137] [PMID: 31427030]
[http://dx.doi.org/10.1177/0040517517708541]
[http://dx.doi.org/10.1016/j.matpr.2020.05.339]
[http://dx.doi.org/10.1007/s00289-020-03302-4]
[http://dx.doi.org/10.1002/slct.201904054]
[http://dx.doi.org/10.1016/j.ijbiomac.2020.06.090] [PMID: 32553957]