Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa

Title:Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa

Volume: 21 Issue: 23

Author(s): Mohammad Anwar Hossain and Nadezhda A. German*

Affiliation:

• Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX,United States

Keywords: Pseudomonas aeruginosa, virulence factors, quorum sensing, quorum sensing inhibitors.

Abstract: Modulators of quorum sensing pathways in Pseudomonas aeruginosa (PA) gain attention due to their potential therapeutic applications. These chemical agents are viewed as anti-virulence agents capable of increasing the existing therapeutic agents’ efficacy against resistant clinical strains. Additionally, they can be utilized in developing anticancer therapeutics, whole-cell biosensors, and artificial biological systems. In this mini-review, we summarize recent (2015-2021) publications on PA's QS modulation.

Cite this article as:

Hossain Anwar Mohammad and German A. Nadezhda *, Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa, Current Topics in Medicinal Chemistry 2021; 21 (23) . https://dx.doi.org/10.2174/1568026621666210924160004