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Review Article

成人海马神经发生在创伤性脑损伤中的潜在作用

卷 29, 期 19, 2022

发表于: 07 January, 2022

页: [3392 - 3419] 页: 28

弟呕挨: 10.2174/0929867328666210923143713

价格: $65

摘要

创伤性脑损伤(TBI)是年轻人和成人残疾和死亡的严重原因，表现出复杂的病理生理学，包括细胞和分子机制，尚未完全阐明。许多实验和临床研究调查了创伤性脑损伤与大脑中神经元形成的过程之间的潜在关系，这被称为神经发生。目前，还没有针对创伤性脑损伤长期后果的治疗方法，即寻找新的治疗靶点，这是最高科学和临床优先考虑的目标。一些研究评估了旨在改善创伤性脑损伤患者神经发生的治疗的好处。在这种情况下，我们回顾了目前的临床前研究，这些研究评估了改善创伤性脑损伤后神经发生的不同方法，同时获得更好的认知结果，这可能包括未来治疗的有趣的方法。

关键词: 创伤性脑损伤，神经发生，海马，模型，动物，齿状回，治疗学。

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