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Mini-Reviews in Medicinal Chemistry

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ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

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Mini-Review Article

Electrospinning: New Strategies for the Treatment of Skin Melanoma

Author(s): Javier Mauricio Anaya Mancipe, Franz Acker Lobianco, Marcos Lopes Dias and Rossana Mara da Silva Moreira Thiré*

Volume 22, Issue 4, 2022

Published on: 12 July, 2021

Page: [564 - 578] Pages: 15

DOI: 10.2174/1389557521666210712111809

Price: $65

Abstract

Recent studies have shown a significant growth of skin cancer cases in northern regions of the world, in which its presence was not common. Skin cancer is one of the cancers that mostly affects the world’s population, ranking fifth in studies conducted in the United States (USA). Melanoma is cancer that has the highest number of deaths worldwide since it is the most resistant skin cancer to current treatments. This is why alternatives for its treatment has been investigated considering nanomedicine concepts. This study approaches the role of this field in the creation of promising electrospun devices, composed of nanoparticles and nanofibers, among other structures, capable of directing and/or loading active drugs and/or materials with the objective of inhibiting the growth of melanoma cells or even eliminating those cells.

Keywords: Skin melanoma, nanofibers, electrospinning, drug delivery, dressings, nanomedicine.

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