Synthetic and Biological Attributes of Pyrimidine Derivatives: A Recent Update

Title:Synthetic and Biological Attributes of Pyrimidine Derivatives: A Recent Update

Volume: 18 Issue: 8

Author(s): Meenu Devi*, Shivangi Jaiswal, Sonika Jain, Navjeet Kaur and Jaya Dwivedi

Affiliation:

• Department of Chemistry, Banasthali Vidyapith,, Banasthali-304022,India

Keywords: Heterocycles, pyrimidine, synthesis, coupling reactions, green methods, anticancer .

Abstract: Nitrogen-containing heterocycles attract the attention of chemists due to their multifarious activities. Amongst all, pyrimidine plays a central role and exhibits a broad spectrum of biological activities. Literature is replete with various aspects of synthetic development in the chemistry of pyrimidine for a wide array of applications. It aroused our interest to compile various novel and efficient synthetic approaches towards the synthesis of pyrimidine and its derivatives. Pyrimidine derivatives are broadly useful as therapeutic agents, owing to their high degree of structural diversity. They have been recorded to possess a diverse range of therapeutic activities viz. anticancer, anti-inflammatory, anti-HIV etc.

Cite this article as:

Devi Meenu *, Jaiswal Shivangi , Jain Sonika, Kaur Navjeet and Dwivedi Jaya , Synthetic and Biological Attributes of Pyrimidine Derivatives: A Recent Update, Current Organic Synthesis 2021; 18 (8) . https://dx.doi.org/10.2174/1570179418666210706152515